recovery cbd reviews

Recovery cbd reviews

While those seem like potentially huge breakthroughs, CBD is also said to help with smaller stuff, like helping you recover faster from workouts thanks to its anti-inflammatory properties. Before you dive into a pool of CBD oil, here’s everything you need to know.

Cool. So, what exactly is CBD again?

According to a 2018 review of 132 original studies published in Frontiers in Neurology, CBD can indeed reduce inflammation in the body and help improve pain and mobility in patients with multiple sclerosis. “It is anti-inflammatory, antioxidative, antiemetic, antipsychotic, and neuroprotective,” the review study’s authors wrote.

Is there scientific proof?

“As a personal trainer and someone that works out every day and really pushes myself a lot, I noticed the biggest difference in inflammation and stress after a workout,” Tara Laferrara, a former sprinter and a NASM certified personal trainer, told MensHealth.com about her personal use of CBD.

The precise mechanism(s) underpinning the neuroprotective effects of CBD are not completely understood (see Campos et al. [25] for review), but may involve decreased inflammation, oxidative stress, and excitotoxicity [142, 143] and increased neurogenesis [129]. Preclinical studies have also demonstrated beneficial effects of CBD in other animal models of neurodegeneration (e.g. transgenic model of Alzheimer’s disease [34, 35], brain iron-overload [47, 48]). Collectively, these data suggest that research investigating the utility of CBD in ameliorating the harmful long-term effects of repeated sports concussions is warranted.

Oral human equivalent CBD doses from mouse and rat intraperitoneal doses

Persistent pain is common in athletes [74]. Nociceptive pain, which includes inflammatory pain, typically occurs with tissue damage; whereas neuropathic pain typically results from a lesion or disease in the somatosensory nervous system [74]. Neuropathic pain is common among para-athletes with spinal cord injuries and can also arise with surgery (e.g. to treat an existing injury) or if there is repetitive mechanical and/or inflammatory irritation of peripheral nerves (e.g. as in endurance sports) [74].

14–17 h. Although tmax did not increase dose-dependently in this investigation [170], another study [19], involving a much lower oral dose of CBD (300 mg), did indicate a shorter tmax (i.e.

Neuroprotection—Concussion and Subconcussion

The available evidence is preliminary, at times inconsistent, and largely based on preclinical studies involving laboratory animals.

Rigorous, controlled investigations clarifying the utility of CBD in the sporting context are warranted.

CBD also interacts with many other non-endocannabinoid signalling systems [92]. Briefly, at concentrations ≤ 10 μM, CBD has been reported to interact with the serotonin 1A [5-HT1A] receptor, the orphan G protein-coupled receptor 55, as well as the glycine, opioid, and peroxisome proliferator-activated receptors, various ion channels (e.g. the transient potential vanilloid receptor type 1 channel [TRPV1] and other transient potential vanilloid channels) and various enzymes (e.g. cyclooxygenase (COX)1 and COX2, cytochrome P450 enzymes) [11, 92] (see Ibeas et al. [92] for review). CBD also possesses antioxidant properties [92].

Table 1

1.5 mg·kg −1 , i.p.) have indicated efficacy in some studies [145]. Research investigating the effects of CBD on inflammation in humans is limited and inconclusive [94, 133].

7-fold higher than oral dosing in mice [52]. Thus, an “oral equivalent dose” can be approximated by multiplying the i.p. dose by seven [9] (Table ​ (Table1). 1 ). Intravenous (i.v.) dosing will produce even higher plasma CBD concentrations; however, the authors are not aware of any published data that would facilitate conversion between i.v. and oral dosing in rodents. Please note that these values are intended as a guide only and subject to limitations (e.g. interspecies differences in drug potency and receptor expression/configuration).

Recovery cbd reviews

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