There is no recorded overdose of CBD, and the WHO has declared it safe.
Bioavailability of CBD: Capsules, Pills, Edibles
Similar to CBD, turmeric isn’t highly bioavailable.
At the time this article is published, specific data around the bioavailability of human-based transdermal CBD isn’t something we have come across yet in a study. However, there is still some interesting information available which we have shared below.
What Is The Future Of CBD oil?
Innovations in cannabis science, borrowing methodologies applied in other supplement niches such as vitamins have been utilised to create CBD products with a much higher (hypothesised) bioavailability.
Researchers interested in the use of black pepper as a tool to improve the bioavailability of turmeric classified piperine as an active compound of interest in improving absorption.
Where CBD oil drops and vapes have a bioavailability of approx 30%/55%.
Transdermal And Topical CBD
Bioequivelence is just a fancy term for working on the same dose you would need for another consumption method to deliver the same amount to your bloodstream.
Oral CBD products are relatively popular, especially with people who are unable to use CBD tinctures for one reason or another. Edibles are also a booming segment, with CBD gummies becoming more commonplace day by day.
Two things impact bioavailability:
Full spectrum means you maintain all ingredients found in the hemp flower. This means that full spectrum products have .3% or less THC because it doesn’t strip anything out, and there is research that shows this is more effective than CBD extracted alone, which would be called isolate. Broad Spectrum is when only the THC is removed but all other ingredients and cannabinoids are maintained. The best way to think of full spectrum and isolate is an orange versus a vitamin C pill, with broad spectrum acting more like a full spectrum product.
Nanoemulsion is a way to make oils blend well in water by making the particle size much smaller, thus making it water-soluble (read: able to be absorbed more quickly and better by your body). There is also water-soluble CBD on the market, which is what you’re typically drinking when you have a CBD drink (and thus your body can absorb more).
Now that you know a bit about bioavailability by product type, let’s talk about the different versions of supplements you find in the CBD world: