Results: A total number of 252 participants identifying as suffering endometriosis recorded 16193 sessions using cannabis between April 2017 and February 2020. The most common method of ingestion was inhalation (n = 10914, 67.4%), with pain as the most common reported symptom being treated by cannabis (n = 9281, 57.3%). Gastrointestinal symptoms, though a less common reason for cannabis usage (15.2%), had the greatest self-reported improvement after use. Inhaled forms had higher efficacy for pain, while oral forms were superior for mood and gastrointestinal symptoms. Dosage varied across ingestion methods, with a median dose of 9 inhalations (IQR 5 to 11) for inhaled dosage forms and 1 mg/mL (IQR 0.5 to 2) for other ingested dosage forms. The ratio of THC to CBD had a statistically significant, yet clinically small, differential effect on efficacy, depending on method of ingestion.
Background: The use of cannabis for symptoms of endometriosis was investigated utilising retrospective archival data from Strainprint Technologies Ltd., a Canadian data technology company with a mobile phone application that tracks a range of data including dose, mode of administration, chemovar and their effects on various self-reported outcomes, including pelvic pain.
Methods: A retrospective, electronic record-based cohort study of StrainprintTM users with self-reported endometriosis was conducted. Self-rated cannabis efficacy, defined as a function of initial and final symptom ratings, was investigated across the included symptom clusters of cramps, pelvic pain, gastrointestinal pain, nausea, depression, and low libido. Cannabis dosage form, dose and cannabinoid ratio information was also recorded.
Conclusions: Cannabis appears to be effective for pelvic pain, gastrointestinal issues and mood, with effectiveness differing based on method of ingestion. The greater propensity for use of an inhaled dosage delivery may be due to the rapid onset of pain-relieving effects versus the slower onset of oral products. Oral forms appeared to be superior compared to inhaled forms in the less commonly reported mood or gastrointestinal categories. Clinical trials investigating the tolerability and effectiveness of cannabis for endometriosis pain and associated symptoms are urgently required.
Although we don’t know the true cause of endometriosis, there are a few popular theories. One theory is that endometriosis arises from retrograde menstruation, which is when menstrual blood flows back through the fallopian tubes and into the pelvic cavity (instead of exiting through the vagina). Another theory is that hormones could mistakenly transform cells outside of the uterus into endometrial cells. There are still more theories, but none have been confirmed.
CBD For Endometrial Pain
Juna created the Ease Collection specifically with our endometriosis community in mind. It has a complex ratio of CBG:CBD with added anti-inflammatory agents like turmeric. Juna’s Ease collection helps tackle endo pain from the inside and out with the ingestible and topical formats.
Is CBD Right For Me?
Seeking an effective treatment for endometriosis can be exhausting and often disappointing. Although endometriosis is common and affects about 11% of women in the U.S., there is no medical cure for this disorder. This lack of effective treatments is why many women are turning to natural medicine for relief – and discovering CBD.