“If you take 35 to 50 milligrams of oral CBD every single day, it will accumulate in your blood,” leading to potential benefits like less inflammation and anxiety, she said.
Since most edibles are dosed in 5, 10, and 20 milligram segments, eating or drinking edible CBD on a whim won’t offer any benefits, said Rae.
As the adult use market expands in the United States with more states legalizing weed, and the unregulated CBD market grows in tandem, customers have become overwhelmed with cannabis options, which can make picking the best and most reliable product for your needs confusing.
“So if you’re taking a 100 milligram CBD capsule or something, you might get five milligrams into your bloodstream. And that’s a whopping dose, right?” Rae said on the podcast.
To get benefits, you must take CBD edibles consistently
There are non-edible ways to use CBD that will skip your liver and go straight to your blood stream, host Twilley mentioned.
During an episode of the podcast “Gastropod” called “It’s All Going to Pot,” neuroscientist and cannabis researcher Adie Rae explained why CBD edibles and beverages are “pointless” and a waste of money. Rae, a National Institute on Drug Abuse-funded researcher at Legacy Research Institute, uses the name Adie Wilson-Poe to publish her work.
If you’re set on using edibles, the best way to reap CBD’s potential benefits is to take it daily, according to Rae.
You can also use CBD in lotions and tinctures
Only a small and inconclusive body of research exists on the benefits of CBD. Current research suggests the cannabinoid can help with anxiety and seizures, Insider’s Gabby Landsverk previously reported.
If you’re looking to experience CBD’s purported benefits, like reduced anxiety, pain, and nausea, taking it occasionally may not do the trick.
CBD and THC have the same molecular structure, but there are differences in how these molecules are arranged that are responsible for the differing effects they have. By mimicking endocannabinoids, they bind with receptors and cause different effects in the body.
Both CBD and THC have a chemical structure that is similar to the body's natural endocannabinoids. Endocannabinoids are neurotransmitters that act in the brain.
While cannabis itself has not been FDA approved to treat any condition, there are a few drugs approved by the U.S. Food and Drug Administration (FDA) that contain CBD or THC.
NIDA also notes that THC alters how the hippocampus and orbitofrontal cortex function. These areas of the brain are important in the formation of new memories and the ability to shift attention from one thing to the next. This not only affects a person’s ability to learn and form new memories, but it also makes it difficult for people to perform difficult tasks.
THC and CBD have an effect on the endocannabinoid system, a system that plays an important role in maintaining homeostasis. Researchers are still working to understand the ins and outs of this complex system, but they do know that it is associated with processes including memory, appetite, sleep, mood, and fertility.