cbd sublingual how long

Cbd sublingual how long

The metabolic rate of the individual also has some sway over how long CBD stays in the system. The body’s metabolism determines the time needed to break down and synthesize compounds, which affects how long it takes the body to process and metabolize the cannabinoid.

The most common method for CBD consumption involves administering a couple of drops directly into the mouth. Swallowing the oil will prevent the CBD from immediately entering your bloodstream, sending it instead through the digestive tract and eventually on to the liver, where it is broken down before finally reaching the bloodstream.

When you apply topical CBD products directly to your skin, the CBD is absorbed and slowly interacts with localized cannabinoid receptors. In some cases, CBD-infused topicals should be applied liberally to overcome the low cannabinoid absorption rate of the skin. With topical application, any CBD effects you feel will peak after about 90 minutes. This method of administration is often used for chronic pain in specific areas.

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When cannabidiol is introduced to the endocannabinoid system, it inhibits the absorption of anandamide, a natural cannabinoid molecule that regulates pain. Photo by: Gina Coleman/Weedmaps

Bottom line: Expect to feel the effects of sublingual administration within 30 minutes. Any effects you feel should last an hour or more but be bolstered at about two hours.

CBD also interacts with other receptor proteins not directly related to the ECS, such as the serotonin receptor 5-HT1A and vanilloid receptor TRPV1. Any potential anti-inflammatory and pain-relieving properties of CBD could stem from the activation of these additional biological pathways.

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Some people may be apprehensive to try CBD over concerns that it could cause them to fail a drug test. It’s highly unlikely that CBD would show up on most drug screenings, as most tests specifically look for the presence of THC and THC metabolites. But even hemp-derived CBD can contain trace amounts of THC, so there’s technically a chance — albeit extremely slim — of receiving a false-positive test result from taking an unusually large dose of CBD oil (estimates range from 1,000 to 2,000 milligrams per day).

In this article, we’ll answer these questions and cover how different consumption methods will alter your CBD experience.

Cbd sublingual how long

Even so, Kater says that “most of the literature supports the notion that CBD has better bioavailability when consumed sublingually versus orally. [and] MCT oil-based tinctures are thought to provide better uptake than a traditional oil.” But, again, there’s no evidence that this applies to the exact CBD oil or tincture that you, specifically, have in your cabinet. As mentioned before, every formulation is different, and those small differences matter when it comes to bioavailabilty.

According to Timothy Birdsall, ND—a member of hemp education platform Prima’s medial advisory group—when you take certain substances sublingually, they can enter directly into your bloodstream, where they’re immediately shuttled to your tissues. Think of it as a shortcut to digestion, which is a longer process in which the substance needs to be ingested, broken down by the stomach, absorbed by the small intestine, and metabolized by the liver. “Not only do many compounds lose potential bioavailability during [the digestion] process, but the time to onset is delayed,” adds chemist Jessie Kater, senior vice president of manufacturing for Curaleaf and Curaleaf Hemp.

How does this apply to CBD? Surprise, surprise: It’s hard to say. “There has been very little scientific research on the sublingual absorption of CBD,” says Dr. Birdsall. The research that does exist has some inconsistencies, adds Kater, since there are so many factors that affect absorption—such as the quality of the CBD or the pH and consistency of the formulation. Plus, many of these studies focus on formulas that contain both CBD and THC—a psychoactive compound found in cannabis that’s supposed to be absent from CBD-only products—so it’s unclear whether their findings would also apply to a product that contains predominantly CBD.

To find out—because there’s been relatively little rigorous research on CBD to date and I’m a skeptic by nature—I reached out to a doctor and a scientist for the 411. As I suspected, this isn’t a topic that has been studied in depth. Yet there is some reason to believe that certain CBD products may truly be more bioavailable when absorbed under the tongue than if taken through food or drink.

Long story short: You may as well try holding your CBD oil or tincture under your tongue before swallowing it—you could find that you feel it working slightly faster. Anecdotally, says Dr. Birdsall, experts recommended that you hold it there for at least 60 seconds. (A word of warning: There will be drool.) Your other option is to try a product that’s specifically created to be absorbed sublingually, like Kin Slips, which are kind of like those breath-freshening films that dissolve in your mouth.

Sublingual delivery isn’t always a better option for all substances, points out Dr. Birdsall—some B vitamins, for instance, need to be “activated” by the liver in order to do their jobs—but for certain vitamins and medications, it can be a super effective delivery method.

After all, if there’s one thing that can be said about the wild west of CBD, it’s that experimentation is key—whether you’re looking for your perfect dose or your perfect delivery method.

Here are 6 products that CBD experts use themselves—including a tonic you can put under your tongue. No matter which CBD option you choose, make sure it doesn’t *just* contain hemp seed oil.