CBD may work within the endocannabinoid system to reduce anxiety or stress. This internal system regulates the release of stress hormones like adrenaline and cortisol. When you take CBD, it binds to cannabinoid receptors and has the potential to modulate your body’s response to stress. But CBD works differently depending on application method, dosage, and your condition. For example, those who feel anxious before public speaking will require a different form of relief from those with stress or anxiety disorders.
You may have noticed that the doses of CBD used in the clinical trials mentioned earlier were in the hundreds of milligrams. These high doses are far above what the average user would normally take. When considering dosage, it’s a good idea to look at the recommended serving size on the packaging. The concentration, or amount of CBD in the product, will likely be prominently displayed on the product’s exterior.
What the science says
To relieve anxiety before a presentation, you can take CBD a few minutes before, or an hour or so in advance depending on the application method you’re using. For example, if you take a capsule, you’ll need to allow extra time for the product to be digested and enter your bloodstream. But if you are using a sublingual tincture, you’ll feel the effects much more quickly.
If you’re using a vape, it’s okay to wait until you’re almost ready to go before inhaling since these kinds of products work almost immediately. Just keep in mind that the effects will wear off quicker than they would had you used another application method. If you use capsules or gummies, you’ll feel the effects longer, but you might want to give the product enough time to start alleviating your symptoms.
What to know before trying CBD
Many studies testing the efficacy of CBD on anxiety place subjects in a public speaking setting.
A study published in the February issue of the Journal of Psychiatry found that 300 milligrams of cannabidiol (CBD) was effective in reducing public speaking anxiety. (Photo by Teemu Paananen/Unsplash)
@kellysikkema Cannabidiol (CBD) products have shown promise in addressing anxiety in many people, though the exact effects depend on the makeup of a person’s endocannabinoid system (ECS). (Weedmaps News File Photo)
Cannabis Dosing Not an Exact Science Yet
CBD interacts with our bodies through our endocannabinoid system (ECS) , which regulates our bodies, returns us to a state of internal balance, and triggers our responses to cannabis compounds, or cannabinoids . The ECS is present throughout the entire body, consisting of three main components : cannabinoid receptors, endocannabinoids (or internal cannabinoids), and the enzymes that break them down. CBD sets off a response in the body by binding to cannabinoid receptors. Genetic mutations of these receptors may cause the body’s response to CBD to vary from person to person.
For example, scientists have identified nine variations of the human CB1 receptor gene. CB1 is one of two cannabinoid receptors with which CBD interacts. If you’re walking around with one of nine variations of the CB1 receptor, your body’s response to CBD may differ from that of your friend with a different variation. Such variables in the ECS make it impossible to guarantee 300 milligrams of CBD will effectively treat your public speaking anxiety. But given the extremely low risk associated with consuming CBD , even in large amounts, it may be worth a shot to experiment with moderate doses and see what works for you.
The study involved a simulated public speaking test where subjects were given doses of CBD from 150 to 600 milligrams. The control group was given a placebo. After measuring blood pressure and heart rates, as well as subject ratings on the Visual Analogue Mood Scale , a test for measuring specific mood states, the study concluded that 300 milligrams of CBD were most effective in reducing anxiety associated with public speaking.