Both CBD and turmeric are thought to have great benefits for inflammation and ridding the body of toxins. But how does it work? The CBD and curcumin helps create a synergistic response, where the two substances together are greater than the effect provided by each on its own… Learn more about TURMERIC uses, effectiveness, possible side effects, interactions, dosage, user ratings and products that contain TURMERIC.
Whats the deal with….CBD and turmeric?
If CBD and turmeric offer potential benefits for inflammation, could it make sense to combine both?
15th August 2021
Both CBD and turmeric are thought to have great benefits for inflammation and ridding the body of toxins. They are now being combined as food, capsules, oil and coffees. But how does it work?
Turmeric is the spice that gives curries a vibrant yellow colour. It comes from the root of a plant called Curcuma longa. For centuries the compound curcumin contained in turmeric has been used in Indian medicine as an anti-oxidant. It also may have potential anti-inflammatory properties. This makes it perfect for helping to boost the similar properties that are associated with CBD.
There have been a few recent reviews and trials on turmeric for knee pain and arthritis.
A review from this year on turmeric for anti-inflammatory has revealed it may help with osteoarthritis (OA). The researchers concluded that over the ten studies examined when compared with a placebo, there appears to be a benefit of turmeric on knee OA pain and function.
In a small study from 2020 on 70 patients diagnosed with knee arthritis, it was discovered that those taking turmeric reported less knee pain.
CBD has also shown potential for soothing arthritic pain. In one study, researchers treated arthritic rats with a topical form of CBD. The rats showed a difference in inflammation levels and their condition was less developed.
It is unknown how CBD and turmeric combine. As they have main similar properties, it could be beneficial to combine both for certain conditions such as osteoarthritis.
One difficulty with taking turmeric is that it is incredibly hard to absorb due to its hydrophobic nature. This causes the molecules to stick together when they come into contact with water in the body. It is thought that adding pepper to turmeric will increase the absorption rate by 2000 percent.
Both CBD and turmeric have low bioavailability making it difficult to absorb them easily. However, they are both lipophilic which means adding fat can help them absorb better.
How to take CBD and turmeric
This is why CBD and turmeric as supplements come with an oil base. Different companies use different bases including rapeseed, hemp or flaxseed oil. Taking these compounds suspended in an oil automatically makes them more easily absorbed. The oil can be popped under the tongue for a few minutes before being swallowed.
Food and drink
Taking CBD and turmeric in food may be less effective than oil. Turmeric is often added to coffee as a latte which CBD can be dropped into. The lower level of fat in the drink, or in certain foods can make it unreliable for absorption but very tasty. Another problem is that the food has to travel through the digestive system first before any of the CBD or turmeric can be absorbed. Digestive acids and enzymes destroy some of the CBD before it can be absorbed. The small amount that gets through the intestinal wall will then be metabolised by the liver before it reaches the rest of the body.
Unfortunately, capsules are also subject to being passed through the digestive system. This could give a slower effect in comparison to the oil which is absorbed through the oral mucous membranes much faster.
CBD with curcumin provides one-two punch for pain, inflammation
CBD and curcumin helps create a synergistic response, where the two together are greater than the effect provided by each on its own
Research reveals that chronic inflammatory diseases are expected to “increase persistently” through the year 2050. This means continuously elevating rates of diabetes, heart disease, arthritis, cancer, chronic respiratory diseases, and even allergies – an environment primed for the new CBD and curcumin anti-inflammatory combination.
Many factors can contribute to this increased chronic inflammation in the body. Regular exposure to environmental pollutants and toxins, poor diet, lack of exercise, chronic stress, and a dysfunctional immune system can all lead to elevated inflammation levels and susceptibility to viruses.
One way to help patients potentially reduce their body’s inflammation is by recommending anti-inflammatory supplements. Two all-natural ingredients that have been scientifically shown to provide this effect are CBD and curcumin.
CBD and inflammation
CBD stands for cannabidiol and is one of many cannabinoids found in the hemp plant. Unlike tetrahydrocannabinol (THC), CBD does not create a psychoactive effect. It works by interacting with the body’s endocannabinoid system and influencing receptor activity, resulting in lower levels of inflammation and pain.
A 2010 study published in the journal Future Medicinal Chemistry calls cannabinoids “novel anti-inflammatory drugs” due to their impact on immune cells located in the body’s CB1 and CB2 receptors. Specifically, cannabinoids have been found to suppress cytokine and chemokine production while increasing the response of T-regulatory cells.
This study further indicates that cannabinoids offer a protective effect as well by stopping the normal death of nontransformed cells in the central nervous system. This is beneficial in cases where autoimmune conditions such as multiple sclerosis exist.
The National Institute on Drug Abuse adds that, though clinical trials are still ongoing in this area, CBD appears to also offer analgesic, anti-tumor, anti-psychotic, anti-anxiety, and anti-seizure effects.
Curcumin as an anti-inflammatory
Curcumin, an active ingredient in turmeric, has also been found to have anti-inflammatory properties as well.
In a 2017 review of curcumin’s effects on health, researchers noted that turmeric can help in the management of inflammatory conditions. It also offers benefits with regard to inflammation caused by exercise, helping to reduce the resulting muscle soreness and improve recovery and performance.
A 2013 study in the British Journal of Pharmacology explains that curcumin works by blocking the action and production of the cytokine TNF -α. Furthermore, it offers patients an orally-bioavailable treatment option that is safe and less expensive than many prescription drugs designed to provide the same effect.
The synergy of combined CBD and curcumin supplements
Some manufacturers are now offering supplemental products that include both CBD and curcumin. This combination product helps create a synergistic response, which states that the effect of two substances together is often greater than the effect provided by each on its own.
In addition to being more powerful, a combination CBD and curcumin supplement provides patients a simpler anti-inflammatory supplemental regimen. Instead of having to buy two individual supplements — which can also mean increased cost — the patient is able to achieve the same (or better) effect with one.
Helping patients select a quality CBD and curcumin supplement
Sometimes patients purchase a low-quality supplement and, therefore, don’t get the results they expect. This experience causes them to lack belief in the value of supplements. That’s why it’s helpful to educate patients about the differences between a high-quality and low-quality supplement.
Higher quality supplements are those that, first and foremost, are made with high-quality ingredients. In the CBD world, this means using a good strain of hemp, but also the product containing full-spectrum CBD. This means that, in addition to CBD, it also contains other cannabinoids found in the hemp plant, providing even more health-related benefits.
Higher quality supplements are also those created by following Good Manufacturing Practice (GMP). These supplements have undergone rigorous testing, further reinforcing their safety and efficacy.
Explaining this to patients help them better understand that not all supplements are created equal. It also helps them recognize that if they’re not getting the results they desire, it is possible that it is that specific supplement — and not the ingredient it contains — that is potentially the cause.
Educating patients about bioavailability
Part of the supplemental discussion includes talking about the amount of ingredients a product contains versus how much of those substances the body can actually use.
It’s not uncommon for people to think that their body is able to effectively absorb the total amount of the vitamins, minerals, and other ingredients contained in a particular supplement. However, this is not always the case.
Bioavailability can be impacted by a number of factors. Dosage amount, product form, method of intake, and the body’s ability to metabolize that ingredient can all impact the amount it is able to actually use.
For this reason, it’s helpful if the supplement contains ingredients that aid in bioavailability. This can increase the effect of the product simply by making more of the anti-inflammatories available for use.
TURMERIC – Uses, Side Effects, and More
Turmeric is a common spice that comes from the root of Curcuma longa. It contains a chemical called curcumin, which might reduce swelling.
Turmeric has a warm, bitter taste and is frequently used to flavor or color curry powders, mustards, butters, and cheeses. Because curcumin and other chemicals in turmeric might decrease swelling, it is often used to treat conditions that involve pain and inflammation.
People commonly use turmeric for osteoarthritis. It is also used for hay fever, depression, high cholesterol, a type of liver disease, and itching, but there is no good scientific evidence to support most of these uses. There is also no good evidence to support using turmeric for COVID-19.
Don’t confuse turmeric with Javanese turmeric root or tree turmeric. Also, don’t confuse it with zedoary or goldenseal, which are unrelated plants that are sometimes called turmeric.
Uses & Effectiveness ?
Possibly Effective for
. Taking turmeric by mouth seems to reduce hay fever symptoms such as sneezing, itching, runny nose, and congestion.
- Depression. Most research shows that taking curcumin, a chemical found in turmeric, by mouth reduces depression symptoms in people already using an antidepressant.
- High levels of cholesterol or other fats (lipids) in the blood (hyperlipidemia). Taking turmeric by mouth seems to lower levels of blood fats called triglycerides. But the effects of turmeric on cholesterol levels are conflicting. Also, there are many different turmeric products available. It is not known which ones work best.
- Buildup of fat in the liver in people who drink little or no alcohol (nonalcoholic fatty liver disease or NAFLD). Taking turmeric extract by mouth reduces markers of liver injury in people who have this condition. It also seems to help prevent the build-up of more fat in the liver.
- Swelling (inflammation) and sores inside the mouth (oral mucositis). Taking curcumin, a chemical found in turmeric, by mouth, or as a lozenge or mouthwash, seems to prevent swelling and sores in the mouth during radiation treatment for cancer.
- Osteoarthritis. Taking turmeric extracts, alone or together with other herbal ingredients, can reduce pain and improve function in people with knee osteoarthritis. Turmeric might work about as well as ibuprofen for reducing pain. But it doesn’t seem to work as well as another drug, called diclofenac.
- Itching. Taking turmeric by mouth might reduce itching that is caused by various conditions.
Possibly Ineffective for
. Taking turmeric, or a chemical in turmeric called curcumin, by mouth does not seem to improve symptoms of Alzheimer disease. ulcers. Taking turmeric by mouth does not seem to improve stomach ulcers.
When taken by mouth: Turmeric is likely safe when used short-term. Turmeric products that provide up to 8 grams of curcumin daily seem to be safe when used for up to 2 months, Also, taking up to 3 grams of turmeric daily seems to be safe when used for up to 3 months. Turmeric usually doesn’t cause serious side effects. Some people can experience mild side effects such as stomach upset, nausea, dizziness, or diarrhea. These side effects are more common at higher doses.
When applied to the skin: Turmeric is likely safe. It is possibly safe when turmeric is applied inside the mouth as a mouthwash.
When applied into the rectum: Turmeric is possibly safe when used as an enema.
Special Precautions and Warnings
When taken by mouth: Turmeric is likely safe when used short-term. Turmeric products that provide up to 8 grams of curcumin daily seem to be safe when used for up to 2 months, Also, taking up to 3 grams of turmeric daily seems to be safe when used for up to 3 months. Turmeric usually doesn’t cause serious side effects. Some people can experience mild side effects such as stomach upset, nausea, dizziness, or diarrhea. These side effects are more common at higher doses.
When applied to the skin: Turmeric is likely safe. It is possibly safe when turmeric is applied inside the mouth as a mouthwash.
When applied into the rectum: Turmeric is possibly safe when used as an enema.
Pregnancy: Turmeric is commonly used in small amounts as a spice in foods. But it’s likely unsafe to use larger amounts of turmeric as a medicine during pregnancy. It might cause a menstrual period or stimulate the uterus, putting the pregnancy at risk. Do not take medicinal amounts of turmeric if you are pregnant.
Breast-feeding: Turmeric is commonly used in small amounts as a spice in foods. But there isn’t enough reliable information to know if turmeric is safe to use in medicinal amounts during breast-feeding. Stay on the safe side and avoid use.
Gallbladder problems: Turmeric can make gallbladder problems worse. Do not use turmeric if you have gallstones or a bile duct obstruction.
Bleeding problems: Taking turmeric might slow blood clotting. This might increase the risk of bruising and bleeding in people with bleeding disorders.
Hormone-sensitive condition such as breast cancer, uterine cancer, ovarian cancer, endometriosis, or uterine fibroids: Turmeric contains a chemical called curcumin, which might act like the hormone estrogen. In theory, this might have effects on hormone-sensitive conditions. Until more is known, use cautiously if you have a condition that might be made worse by exposure to hormones.
Infertility: Turmeric might lower testosterone levels and decrease sperm movement. This might reduce fertility. Turmeric should be used cautiously by people trying to have a baby.
Liver disease: There is some concern that turmeric can damage the liver, especially in people who have liver disease. Don’t use turmeric if you have liver problems.
Surgery: Turmeric might slow blood clotting. It might cause extra bleeding during and after surgery. Stop using turmeric at least 2 weeks before a scheduled surgery.
Be cautious with this combination
Medications that slow blood clotting (Anticoagulant / Antiplatelet drugs) interacts with TURMERIC
Turmeric might slow blood clotting. Taking turmeric along with medications that also slow blood clotting might increase the risk of bruising and bleeding.
Medications for diabetes (Antidiabetes drugs) interacts with TURMERIC
Turmeric might lower blood sugar levels. Taking turmeric along with diabetes medications might cause blood sugar to drop too low. Monitor your blood sugar closely.
Talinolol interacts with TURMERIC
Turmeric might decrease how much talinolol the body absorbs. Taking turmeric while taking talinolol might decrease the effects of talinolol.
Sulfasalazine (Azulfidine) interacts with TURMERIC
Turmeric might increase how much sulfasalazine the body absorbs. Taking turmeric while taking sulfasalazine might increase the effects and side effects of sulfasalazine.
Tacrolimus (Prograf) interacts with TURMERIC
Warfarin (Coumadin) interacts with TURMERIC
Warfarin is used to slow blood clotting. Taking turmeric while taking warfarin might increase the effects of warfarin and increase the risk of bleeding and bruising.
Medications for cancer (Alkylating agents) interacts with TURMERIC
Turmeric is an antioxidant. There is some concern that antioxidants might decrease the effects of some medications used for cancer. If you are taking medications for cancer, check with your healthcare provider before taking turmeric.
Medications for cancer (Antitumor antibiotics) interacts with TURMERIC
Turmeric is an antioxidant. There is some concern that antioxidants might decrease the effects of medications used for cancer. If you are taking medications for cancer, check with your healthcare provider before taking turmeric.
Medications for cancer (Topoisomerase I inhibitors) interacts with TURMERIC
Turmeric is an antioxidant. There is some concern that antioxidants might decrease the effectiveness of some medications used for cancers. If you are taking medications for cancer, check with your healthcare provider before taking turmeric.
Amlodipine (Norvasc) interacts with TURMERIC
Turmeric might increase how much amlodipine the body absorbs. Taking turmeric while taking amlodipine might increase the effects and side effects of amlodipine.
Medications that can harm the liver (Hepatotoxic drugs) interacts with TURMERIC
Turmeric might harm the liver. Some medications can also harm the liver. Taking turmeric along with a medication that can harm the liver might increase the risk of liver damage.
Tamoxifen (Nolvadex) interacts with TURMERIC
Turmeric might decrease how much tamoxifen is in the body. Taking turmeric with tamoxifen might decrease the effects of tamoxifen.
Be watchful with this combination
Medications changed by the liver (Cytochrome P450 1A1 (CYP1A1) substrates) interacts with TURMERIC
Some medications are changed and broken down by the liver. Turmeric might change how quickly the liver breaks down these medications. This could change the effects and side effects of these medications.
Medications changed by the liver (Cytochrome P450 1A2 (CYP1A2) substrates) interacts with TURMERIC
Some medications are changed and broken down by the liver. Turmeric might change how quickly the liver breaks down these medications. This could change the effects and side effects of these medications.
Medications changed by the liver (Cytochrome P450 3A4 (CYP3A4) substrates) interacts with TURMERIC
Some medications are changed and broken down by the liver. Turmeric might change how quickly the liver breaks down these medications. This could change the effects and side effects of these medications.
Estrogens interacts with TURMERIC
Large amounts of turmeric might interfere with the effects of estrogen. Taking turmeric along with estrogen might decrease the effects of estrogens.
Some estrogen pills include conjugated equine estrogens (Premarin), ethinyl estradiol, estradiol, and others.
Norfloxacin (Noroxin) interacts with TURMERIC
Turmeric might increase how much norfloxacin the body absorbs. Taking turmeric while taking norfloxacin might increase the effects and side effects of norfloxacin.
Medications moved by pumps in cells (P-Glycoprotein Substrates) interacts with TURMERIC
Some medications are moved in and out of cells by pumps. Turmeric might change how these pumps work and change how much medication stays in the body. In some cases, this might change the effects and side effects of a medication.
Paclitaxel (Abraxane, Onxol) interacts with TURMERIC
Turmeric might change how much paclitaxel stays in the body. Taking turmeric while taking paclitaxel might change the effects and side effects of paclitaxel. However, this doesn’t seem to be a big concern.
Docetaxel (Taxotere) interacts with TURMERIC
Turmeric might increase how much docetaxel the body absorbs. Taking turmeric while taking docetaxel might increase the effects and side effects of docetaxel.
Glyburide (Diabeta, others) interacts with TURMERIC
Turmeric contains curcumin. Curcumin might lower blood sugar. Glyburide is also used to lower blood sugar. Taking curcumin or turmeric along with glyburide might cause your blood sugar to go too low. Monitor your blood sugar closely. Your dose of glyburide might need to be changed.
Turmeric has most often been used by adults in doses of up to 1.5 grams daily for up to 9 months. It is also sometimes used in mouthwashes, gels, creams, and tonics. Speak with a healthcare provider to find out what dose might be best for a specific condition.
Allam, G. Immunomodulatory effects of curcumin treatment on murine schistosomiasis mansoni. Immunobiology 2009;214(8):712-727. View abstract.
Alves, L. V., Temporal, R. M., Cysne-Finkelstein, L., and Leon, L. L. Efficacy of a diarylheptanoid derivative against Leishmania amazonensis. Mem.Inst.Oswaldo Cruz 2003;98(4):553-555. View abstract.
Arun, N. and Nalini, N. Efficacy of turmeric on blood sugar and polyol pathway in diabetic albino rats. Plant Foods Hum.Nutr. 2002;57(1):41-52. View abstract.
Ashok, P. and Meenakshi, B. Contraceptive effect of Curcuma longa (L.) in male albino rat. Asian J Androl 2004;6(1):71-74. View abstract.
Azuine, M. A. and Bhide, S. V. Chemopreventive effect of turmeric against stomach and skin tumors induced by chemical carcinogens in Swiss mice. Nutr.Cancer 1992;17(1):77-83. View abstract.
Babu, P. S. and Srinivasan, K. Hypolipidemic action of curcumin, the active principle of turmeric (Curcuma longa) in streptozotocin induced diabetic rats. Mol.Cell Biochem. 1997;166(1-2):169-175. View abstract.
Babu, P. S. and Srinivasan, K. Influence of dietary curcumin and cholesterol on the progression of experimentally induced diabetes in albino rat. Mol.Cell Biochem. 11-8-1995;152(1):13-21. View abstract.
Baghdasaryan, A., Claudel, T., Kosters, A., Gumhold, J., Silbert, D., Thuringer, A., Leski, K., Fickert, P., Karpen, S. J., and Trauner, M. Curcumin improves sclerosing cholangitis in Mdr2-/- mice by inhibition of cholangiocyte inflammatory response and portal myofibroblast proliferation. Gut 2010;59(4):521-530. View abstract.
Balasubramanian, K. Molecular orbital basis for yellow curry spice curcumin’s prevention of Alzheimer’s disease. J Agric.Food Chem. 5-17-2006;54(10):3512-3520. View abstract.
Baliga, M. S., Jagetia, G. C., Rao, S. K., and Babu, K. Evaluation of nitric oxide scavenging activity of certain spices in vitro: a preliminary study. Nahrung 2003;47(4):261-264. View abstract.
Bansal, S. and Chhibber, S. Curcumin alone and in combination with augmentin protects against pulmonary inflammation and acute lung injury generated during Klebsiella pneumoniae B5055-induced lung infection in BALB/c mice. J Med.Microbiol. 2010;59(Pt 4):429-437. View abstract.
Bao, H. Y., Chen, R. H., Huang, S. M., Zhang, A. H., Guo, M., Fei, L., and Pan, X. Q. [Effect of curcumin on extracellular matrix accumulation in the glomeruli in nephrotoxic sera nephritis rats]. Zhong.Xi.Yi.Jie.He.Xue.Bao. 2004;2(1):30-32. View abstract.
Bas, M., Tugcu, V., Kemahli, E., Ozbek, E., Uhri, M., Altug, T., and Tasci, A. I. Curcumin prevents shock-wave lithotripsy-induced renal injury through inhibition of nuclear factor kappa-B and inducible nitric oxide synthase activity in rats. Urol.Res 2009;37(3):159-164. View abstract.
Belcaro, G., Cesarone, M. R., Dugall, M., Pellegrini, L., Ledda, A., Grossi, M. G., Togni, S., and Appendino, G. Product-evaluation registry of Meriva(R), a curcumin-phosphatidylcholine complex, for the complementary management of osteoarthritis. Panminerva Med 2010;52(2 Suppl 1):55-62. View abstract.
Biswas, S. K., McClure, D., Jimenez, L. A., Megson, I. L., and Rahman, I. Curcumin induces glutathione biosynthesis and inhibits NF-kappaB activation and interleukin-8 release in alveolar epithelial cells: mechanism of free radical scavenging activity. Antioxid.Redox.Signal. 2005;7(1-2):32-41. View abstract.
Bourne, K. Z., Bourne, N., Reising, S. F., and Stanberry, L. R. Plant products as topical microbicide candidates: assessment of in vitro and in vivo activity against herpes simplex virus type 2. Antiviral Res 1999;42(3):219-226. View abstract.
Bundy, R., Walker, A. F., Middleton, R. W., and Booth, J. Turmeric extract may improve irritable bowel syndrome symptomology in otherwise healthy adults: a pilot study. J Altern.Complement Med. 2004;10(6):1015-1018. View abstract.
Cashman, J. R., Ghirmai, S., Abel, K. J., and Fiala, M. Immune defects in Alzheimer’s disease: new medications development. BMC.Neurosci. 2008;9 Suppl 2:S13. View abstract.
Cekmen, M., Ilbey, Y. O., Ozbek, E., Simsek, A., Somay, A., and Ersoz, C. Curcumin prevents oxidative renal damage induced by acetaminophen in rats. Food Chem.Toxicol 2009;47(7):1480-1484. View abstract.
Chainani-Wu, N. Safety and Anti-Inflammatory Activity of Curcumin: A Component of Tumeric (Curcuma longa). J Altern.Complement Med. 2003;9(1):161-168. View abstract.
Chainani-Wu, N., Madden, E., Lozada-Nur, F., and Silverman S Jr. High-dose curcuminoids are efficacious in the reduction in symptoms and signs of oral lichen planus. J Am Acad Dermatol 2012;66(5):752-760. View abstract.
Chan, M. M., Ho, C. T., and Huang, H. I. Effects of three dietary phytochemicals from tea, rosemary and turmeric on inflammation-induced nitrite production. Cancer Lett. 9-4-1995;96(1):23-29. View abstract.
Chatterjee, S., Variyar, P. S., and Sharma, A. Stability of lipid constituents in radiation processed fenugreek seeds and turmeric: role of phenolic antioxidants. J Agric.Food Chem. 10-14-2009;57(19):9226-9233. View abstract.
Chen, D., Nie, M., Fan, M. W., and Bian, Z. Anti-inflammatory activity of curcumin in macrophages stimulated by lipopolysaccharides from Porphyromonas gingivalis. Pharmacology 2008;82(4):264-269. View abstract.
Chen, H. W. and Huang, H. C. Effect of curcumin on cell cycle progression and apoptosis in vascular smooth muscle cells. Br.J Pharmacol. 1998;124(6):1029-1040. View abstract.
Chen, K. H., Chao, D., Liu, C. F., Chen, C. F., and Wang, D. Curcumin attenuates airway hyperreactivity induced by ischemia-reperfusion of the pancreas in rats. Transplant.Proc. 2010;42(3):744-747. View abstract.
Chen, Z., Zhu, L., Song, T., Chen, J., and Guo, Z. A novel curcumin assay with the metal ion Cu (II) as a simple probe by resonance light scattering technique. Spectrochim.Acta A Mol.Biomol.Spectrosc. 2009;72(3):518-522. View abstract.
Cheng, A. L., Hsu, C. H., Lin, J. K., Hsu, M. M., Ho, Y. F., Shen, T. S., Ko, J. Y., Lin, J. T., Lin, B. R., Ming-Shiang, W., Yu, H. S., Jee, S. H., Chen, G. S., Chen, T. M., Chen, C. A., Lai, M. K., Pu, Y. S., Pan, M. H., Wang, Y. J., Tsai, C. C., and Hsieh, C. Y. Phase I clinical trial of curcumin, a chemopreventive agent, in patients with high-risk or pre-malignant lesions. Anticancer Res 2001;21(4B):2895-2900. View abstract.
Chiu, J., Khan, Z. A., Farhangkhoee, H., and Chakrabarti, S. Curcumin prevents diabetes-associated abnormalities in the kidneys by inhibiting p300 and nuclear factor-kappaB. Nutrition 2009;25(9):964-972. View abstract.
Chopra, A., Lavin, P., Patwardhan, B., and Chitre, D. A 32-week randomized, placebo-controlled clinical evaluation of RA-11, an Ayurvedic drug, on osteoarthritis of the knees. J Clin Rheumatol. 2004;10(5):236-245. View abstract.
Choudhary, D., Chandra, D., and Kale, R. K. Modulation of radioresponse of glyoxalase system by curcumin. J Ethnopharmacol. 1999;64(1):1-7. View abstract.
Chuengsamarn, S., Rattanamongkolgul, S., Luechapudiporn, R., Phisalaphong, C., and Jirawatnotai, S. Curcumin extract for prevention of type 2 diabetes. Diabetes Care 2012;35(11):2121-2127. View abstract.
Ciftci, O., Ozdemir, I., Tanyildizi, S., Yildiz, S., and Oguzturk, H. Antioxidative effects of curcumin, beta-myrcene and 1,8-cineole against 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced oxidative stress in rats liver. Toxicol Ind Health 2011;27(5):447-453. View abstract.
Ciolino, H. P., Daschner, P. J., Wang, T. T., and Yeh, G. C. Effect of curcumin on the aryl hydrocarbon receptor and cytochrome P450 1A1 in MCF-7 human breast carcinoma cells. Biochem.Pharmacol. 7-15-1998;56(2):197-206. View abstract.
Cui, L., Miao, J., and Cui, L. Cytotoxic effect of curcumin on malaria parasite Plasmodium falciparum: inhibition of histone acetylation and generation of reactive oxygen species. Antimicrob.Agents Chemother. 2007;51(2):488-494. View abstract.
Curcumin prevents and reverses murine cardiac hypertrophy. J Clin Invest 2009;119(7):2113. View abstract.
Dandekar, P. P., Jain, R., Patil, S., Dhumal, R., Tiwari, D., Sharma, S., Vanage, G., and Patravale, V. Curcumin-loaded hydrogel nanoparticles: application in anti-malarial therapy and toxicological evaluation. J Pharm Sci 2010;99(12):4992-5010. View abstract.
De, R., Kundu, P., Swarnakar, S., Ramamurthy, T., Chowdhury, A., Nair, G. B., and Mukhopadhyay, A. K. Antimicrobial activity of curcumin against Helicobacter pylori isolates from India and during infections in mice. Antimicrob.Agents Chemother. 2009;53(4):1592-1597. View abstract.
Dorai, T., Cao, Y. C., Dorai, B., Buttyan, R., and Katz, A. E. Therapeutic potential of curcumin in human prostate cancer. III. Curcumin inhibits proliferation, induces apoptosis, and inhibits angiogenesis of LNCaP prostate cancer cells in vivo. Prostate 6-1-2001;47(4):293-303. View abstract.
Dou, X., Fan, C., Wo, L., Yan, J., Qian, Y., and Wo, X. Curcumin up-regulates LDL receptor expression via the sterol regulatory element pathway in HepG2 cells. Planta Med. 2008;74(11):1374-1379. View abstract.
El Agamy, D. S. Comparative effects of curcumin and resveratrol on aflatoxin B(1)-induced liver injury in rats. Arch.Toxicol 2010;84(5):389-396. View abstract.
Epelbaum, R., Schaffer, M., Vizel, B., Badmaev, V., and Bar-Sela, G. Curcumin and gemcitabine in patients with advanced pancreatic cancer. Nutr Cancer 2010;62(8):1137-1141. View abstract.
Eybl, V., Kotyzova, D., and Bludovska, M. The effect of curcumin on cadmium-induced oxidative damage and trace elements level in the liver of rats and mice. Toxicol Lett. 6-15-2004;151(1):79-85. View abstract.
Fan, C., Wo, X., Qian, Y., Yin, J., and Gao, L. Effect of curcumin on the expression of LDL receptor in mouse macrophages. J Ethnopharmacol. 4-21-2006;105(1-2):251-254. View abstract.
Fang, X. D., Yang, F., Zhu, L., Shen, Y. L., Wang, L. L., and Chen, Y. Y. Curcumin ameliorates high glucose-induced acute vascular endothelial dysfunction in rat thoracic aorta. Clin Exp.Pharmacol Physiol 2009;36(12):1177-1182. View abstract.
Fiala, M., Liu, P. T., Espinosa-Jeffrey, A., Rosenthal, M. J., Bernard, G., Ringman, J. M., Sayre, J., Zhang, L., Zaghi, J., Dejbakhsh, S., Chiang, B., Hui, J., Mahanian, M., Baghaee, A., Hong, P., and Cashman, J. Innate immunity and transcription of MGAT-III and Toll-like receptors in Alzheimer’s disease patients are improved by bisdemethoxycurcumin. Proc.Natl.Acad.Sci.U.S A 7-31-2007;104(31):12849-12854. View abstract.
Flynn, D. L., Rafferty, M. F., and Boctor, A. M. Inhibition of 5-hydroxy-eicosatetraenoic acid (5-HETE) formation in intact human neutrophils by naturally-occurring diarylheptanoids: inhibitory activities of curcuminoids and yakuchinones. Prostaglandins Leukot.Med. 1986;22(3):357-360. View abstract.
Frautschy, S. A., Hu, W., Kim, P., Miller, S. A., Chu, T., Harris-White, M. E., and Cole, G. M. Phenolic anti-inflammatory antioxidant reversal of Abeta-induced cognitive deficits and neuropathology. Neurobiol.Aging 2001;22(6):993-1005. View abstract.
Funk, J. L., Frye, J. B., Oyarzo, J. N., Kuscuoglu, N., Wilson, J., McCaffrey, G., Stafford, G., Chen, G., Lantz, R. C., Jolad, S. D., Solyom, A. M., Kiela, P. R., and Timmermann, B. N. Efficacy and mechanism of action of turmeric supplements in the treatment of experimental arthritis. Arthritis Rheum. 2006;54(11):3452-3464. View abstract.
Garcea, G., Berry, D. P., Jones, D. J., Singh, R., Dennison, A. R., Farmer, P. B., Sharma, R. A., Steward, W. P., and Gescher, A. J. Consumption of the putative chemopreventive agent curcumin by cancer patients: assessment of curcumin levels in the colorectum and their pharmacodynamic consequences. Cancer Epidemiol.Biomarkers Prev. 2005;14(1):120-125. View abstract.
Garcia-Alloza, M., Borrelli, L. A., Rozkalne, A., Hyman, B. T., and Bacskai, B. J. Curcumin labels amyloid pathology in vivo, disrupts existing plaques, and partially restores distorted neurites in an Alzheimer mouse model. J Neurochem. 2007;102(4):1095-1104. View abstract.
Ghosh, A. K., Kay, N. E., Secreto, C. R., and Shanafelt, T. D. Curcumin inhibits prosurvival pathways in chronic lymphocytic leukemia B cells and may overcome their stromal protection in combination with EGCG. Clin Cancer Res 2-15-2009;15(4):1250-1258. View abstract.
Goh, C. L. and Ng, S. K. Allergic contact dermatitis to Curcuma longa (turmeric). Contact Dermatitis 1987;17(3):186. View abstract.
Gonda, R., Takeda, K., Shimizu, N., and Tomoda, M. Characterization of a neutral polysaccharide having activity on the reticuloendothelial system from the rhizome of Curcuma longa. Chem.Pharm Bull.(Tokyo) 1992;40(1):185-188. View abstract.
Gonda, R., Tomoda, M., Shimizu, N., and Kanari, M. Characterization of polysaccharides having activity on the reticuloendothelial system from the rhizome of Curcuma longa. Chem.Pharm Bull.(Tokyo) 1990;38(2):482-486. View abstract.
Gonda, R., Tomoda, M., Takada, K., Ohara, N., and Shimizu, N. The core structure of ukonan A, a phagocytosis-activating polysaccharide from the rhizome of Curcuma longa, and immunological activities of degradation products. Chem.Pharm Bull.(Tokyo) 1992;40(4):990-993. View abstract.
Gopalan, B., Goto, M., Kodama, A., and Hirose, T. Supercritical carbon dioxide extraction of turmeric (Curcuma longa). J Agric.Food Chem. 2000;48(6):2189-2192. View abstract.
Gota, V. S., Maru, G. B., Soni, T. G., Gandhi, T. R., Kochar, N., and Agarwal, M. G. Safety and pharmacokinetics of a solid lipid curcumin particle formulation in osteosarcoma patients and healthy volunteers. J Agric.Food Chem 2-24-2010;58(4):2095-2099. View abstract.
Goto, H., Sasaki, Y., Fushimi, H., Shibahara, N., Shimada, Y., and Komatsu, K. Effect of curcuma herbs on vasomotion and hemorheology in spontaneously hypertensive rat. Am.J Chin Med. 2005;33(3):449-457. View abstract.
Grandjean-Laquerriere, A., Gangloff, S. C., Le Naour, R., Trentesaux, C., Hornebeck, W., and Guenounou, M. Relative contribution of NF-kappaB and AP-1 in the modulation by curcumin and pyrrolidine dithiocarbamate of the UVB-induced cytokine expression by keratinocytes. Cytokine 5-7-2002;18(3):168-177. View abstract.
Guimaraes, M. R., Coimbra, L. S., de Aquino, S. G., Spolidorio, L. C., Kirkwood, K. L., and Rossa, C., Jr. Potent anti-inflammatory effects of systemically administered curcumin modulate periodontal disease in vivo. J Periodontal Res 2011;46(2):269-279. View abstract.
Hanai, H., Iida, T., Takeuchi, K., Watanabe, F., Maruyama, Y., Andoh, A., Tsujikawa, T., Fujiyama, Y., Mitsuyama, K., Sata, M., Yamada, M., Iwaoka, Y., Kanke, K., Hiraishi, H., Hirayama, K., Arai, H., Yoshii, S., Uchijima, M., Nagata, T., and Koide, Y. Curcumin maintenance therapy for ulcerative colitis: randomized, multicenter, double-blind, placebo-controlled trial. Clin Gastroenterol.Hepatol. 2006;4(12):1502-1506. View abstract.
He, Z. Y., Shi, C. B., Wen, H., Li, F. L., Wang, B. L., and Wang, J. Upregulation of p53 expression in patients with colorectal cancer by administration of curcumin. Cancer Invest 2011;29(3):208-213. View abstract.
Hergenhahn, M., Soto, U., Weninger, A., Polack, A., Hsu, C. H., Cheng, A. L., and Rosl, F. The chemopreventive compound curcumin is an efficient inhibitor of Epstein-Barr virus BZLF1 transcription in Raji DR-LUC cells. Mol.Carcinog. 2002;33(3):137-145. View abstract.
Ho, S. C., Tsai, T. H., Tsai, P. J., and Lin, C. C. Protective capacities of certain spices against peroxynitrite-mediated biomolecular damage. Food Chem.Toxicol. 2008;46(3):920-928. View abstract.
Holt, P. R., Katz, S., and Kirshoff, R. Curcumin therapy in inflammatory bowel disease: a pilot study. Dig.Dis.Sci. 2005;50(11):2191-2193. View abstract.
Honda, S., Aoki, F., Tanaka, H., Kishida, H., Nishiyama, T., Okada, S., Matsumoto, I., Abe, K., and Mae, T. Effects of ingested turmeric oleoresin on glucose and lipid metabolisms in obese diabetic mice: a DNA microarray study. J Agric.Food Chem. 11-29-2006;54(24):9055-9062. View abstract.
Hu, G. X., Liang, G., Chu, Y., Li, X., Lian, Q. Q., Lin, H., He, Y., Huang, Y., Hardy, D. O., and Ge, R. S. Curcumin derivatives inhibit testicular 17beta-hydroxysteroid dehydrogenase 3. Bioorg.Med.Chem.Lett. 4-15-2010;20(8):2549-2551. View abstract.
Hu, Y., Du, Q., and Tang, Q. [Determination of chemical constituents of the volatile oil from Curcuma longa by gas chromatography-mass spectrometry]. Se.Pu. 1998;16(6):528-529. View abstract.
Huang, C. Y., Chen, J. H., Tsai, C. H., Kuo, W. W., Liu, J. Y., and Chang, Y. C. Regulation of extracellular signal-regulated protein kinase signaling in human osteosarcoma cells stimulated with nicotine. J Periodontal Res 2005;40(2):176-181. View abstract.
Huang, H. C., Jan, T. R., and Yeh, S. F. Inhibitory effect of curcumin, an anti-inflammatory agent, on vascular smooth muscle cell proliferation. Eur.J Pharmacol. 10-20-1992;221(2-3):381-384. View abstract.
Huang, M. T., Deschner, E. E., Newmark, H. L., Wang, Z. Y., Ferraro, T. A., and Conney, A. H. Effect of dietary curcumin and ascorbyl palmitate on azoxymethanol- induced colonic epithelial cell proliferation and focal areas of dysplasia. Cancer Lett. 6-15-1992;64(2):117-121. View abstract.
Huang, M. T., Lysz, T., Ferraro, T., Abidi, T. F., Laskin, J. D., and Conney, A. H. Inhibitory effects of curcumin on in vitro lipoxygenase and cyclooxygenase activities in mouse epidermis. Cancer Res. 2-1-1991;51(3):813-819. View abstract.
Hussain, M. S. and Chandrasekhara, N. Effect on curcumin on cholesterol gall-stone induction in mice. Indian J Med.Res. 1992;96:288-291. View abstract.
Inano, H. and Onoda, M. Radioprotective action of curcumin extracted from Curcuma longa LINN: inhibitory effect on formation of urinary 8-hydroxy-2′-deoxyguanosine, tumorigenesis, but not mortality, induced by gamma-ray irradiation. Int.J Radiat.Oncol.Biol.Phys. 7-1-2002;53(3):735-743. View abstract.
Jain, S. K., Rains, J., Croad, J., Larson, B., and Jones, K. Curcumin supplementation lowers TNF-alpha, IL-6, IL-8, and MCP-1 secretion in high glucose-treated cultured monocytes and blood levels of TNF-alpha, IL-6, MCP-1, glucose, and glycosylated hemoglobin in diabetic rats. Antioxid.Redox.Signal. 2009;11(2):241-249. View abstract.
Jain, V., Prasad, V., Pal, R., and Singh, S. Standardization and stability studies of neuroprotective lipid soluble fraction obtained from Curcuma longa. J Pharm Biomed.Anal. 9-3-2007;44(5):1079-1086. View abstract.
Jayasekera, R., Freitas, M. C., and Araujo, M. F. Bulk and trace element analysis of spices: the applicability of k0-standardization and energy dispersive X-ray fluorescence. J Trace Elem.Med.Biol. 2004;17(4):221-228. View abstract.
Ji, H. F. and Shen, L. Interactions of curcumin with the PfATP6 model and the implications for its antimalarial mechanism. Bioorg.Med.Chem.Lett. 5-1-2009;19(9):2453-2455. View abstract.
Ji, M., Choi, J., Lee, J., and Lee, Y. Induction of apoptosis by ar-turmerone on various cell lines. Int.J Mol.Med. 2004;14(2):253-256. View abstract.
Jiang, H., Timmermann, B. N., and Gang, D. R. Use of liquid chromatography-electrospray ionization tandem mass spectrometry to identify diarylheptanoids in turmeric (Curcuma longa L.) rhizome. J Chromatogr.A 4-7-2006;1111(1):21-31. View abstract.
Joshi, J., Ghaisas, S., Vaidya, A., Vaidya, R., Kamat, D. V., Bhagwat, A. N., and Bhide, S. Early human safety study of turmeric oil (Curcuma longa oil) administered orally in healthy volunteers. J Assoc.Physicians India 2003;51:1055-1060. View abstract.
Juan, H., Terhaag, B., Cong, Z., Bi-Kui, Z., Rong-Hua, Z., Feng, W., Fen-Li, S., Juan, S., Jing, T., and Wen-Xing, P. Unexpected effect of concomitantly administered curcumin on the pharmacokinetics of talinolol in healthy Chinese volunteers. Eur.J Clin Pharmacol 2007;63(7):663-668. View abstract.
Kalpana, C. and Menon, V. P. Curcumin ameliorates oxidative stress during nicotine-induced lung toxicity in Wistar rats. Ital.J Biochem. 2004;53(2):82-86. View abstract.
Kalpana, C. and Menon, V. P. Modulatory effects of curcumin on lipid peroxidation and antioxidant status during nicotine-induced toxicity. Pol.J Pharmacol 2004;56(5):581-586. View abstract.
Kanai, M., Imaizumi, A., Otsuka, Y., Sasaki, H., Hashiguchi, M., Tsujiko, K., Matsumoto, S., Ishiguro, H., and Chiba, T. Dose-escalation and pharmacokinetic study of nanoparticle curcumin, a potential anticancer agent with improved bioavailability, in healthy human volunteers. Cancer Chemother.Pharmacol 2012;69(1):65-70. View abstract.
Kaur, G., Tirkey, N., Bharrhan, S., Chanana, V., Rishi, P., and Chopra, K. Inhibition of oxidative stress and cytokine activity by curcumin in amelioration of endotoxin-induced experimental hepatoxicity in rodents. Clin Exp.Immunol. 2006;145(2):313-321. View abstract.
Kawamori, T., Lubet, R., Steele, V. E., Kelloff, G. J., Kaskey, R. B., Rao, C. V., and Reddy, B. S. Chemopreventive effect of curcumin, a naturally occurring anti- inflammatory agent, during the promotion/progression stages of colon cancer. Cancer Res 2-1-1999;59(3):597-601. View abstract.
Khajehdehi, P., Zanjaninejad, B., Aflaki, E., Nazarinia, M., Azad, F., Malekmakan, L., and Dehghanzadeh, G. R. Oral supplementation of turmeric decreases proteinuria, hematuria, and systolic blood pressure in patients suffering from relapsing or refractory lupus nephritis: a randomized and placebo-controlled study. J Ren Nutr 2012;22(1):50-57. View abstract.
Kheradpezhouh, E., Panjehshahin, M. R., Miri, R., Javidnia, K., Noorafshan, A., Monabati, A., and Dehpour, A. R. Curcumin protects rats against acetaminophen-induced hepatorenal damages and shows synergistic activity with N-acetyl cysteine. Eur.J Pharmacol 2-25-2010;628(1-3):274-281. View abstract.
Kiec-Swierczynska, M. and Krecisz, B. Occupational allergic contact dermatitis due to curcumin food colour in a pasta factory worker. Contact Dermatitis 1998;39(1):30-31. View abstract.
Kim, D. S., Park, S. Y., and Kim, J. K. Curcuminoids from Curcuma longa L. (Zingiberaceae) that protect PC12 rat pheochromocytoma and normal human umbilical vein endothelial cells from betaA(1-42) insult. Neurosci.Lett. 4-27-2001;303(1):57-61. View abstract.
Kim, H. J. and Jang, Y. P. Direct analysis of curcumin in turmeric by DART-MS. Phytochem.Anal. 2009;20(5):372-377. View abstract.
Kim, H. J., Yoo, H. S., Kim, J. C., Park, C. S., Choi, M. S., Kim, M., Choi, H., Min, J. S., Kim, Y. S., Yoon, S. W., and Ahn, J. K. Antiviral effect of Curcuma longa Linn extract against hepatitis B virus replication. J Ethnopharmacol. 7-15-2009;124(2):189-196. View abstract.
Kim, K., Kim, K. H., Kim, H. Y., Cho, H. K., Sakamoto, N., and Cheong, J. Curcumin inhibits hepatitis C virus replication via suppressing the Akt-SREBP-1 pathway. FEBS Lett. 2-19-2010;584(4):707-712. View abstract.
Koosirirat, C., Linpisarn, S., Changsom, D., Chawansuntati, K., and Wipasa, J. Investigation of the anti-inflammatory effect of Curcuma longa in Helicobacter pylori-infected patients. Int Immunopharmacol. 2010;10(7):815-818. View abstract.
Korutla, L. and Kumar, R. Inhibitory effect of curcumin on epidermal growth factor receptor kinase activity in A431 cells. Biochim.Biophys.Acta 12-30-1994;1224(3):597-600. View abstract.
Kusuhara, H., Furuie, H., Inano, A., Sunagawa, A., Yamada, S., Wu, C., Fukizawa, S., Morimoto, N., Ieiri, I., Morishita, M., Sumita, K., Mayahara, H., Fujita, T., Maeda, K., and Sugiyama, Y. Pharmacokinetic interaction study of sulphasalazine in healthy subjects and the impact of curcumin as an in vivo inhibitor of BCRP. Br J Pharmacol 2012;166(6):1793-1803. View abstract.
Kutluay, S. B., Doroghazi, J., Roemer, M. E., and Triezenberg, S. J. Curcumin inhibits herpes simplex virus immediate-early gene expression by a mechanism independent of p300/CBP histone acetyltransferase activity. Virology 4-10-2008;373(2):239-247. View abstract.
Kuwabara, N., Tamada, S., Iwai, T., Teramoto, K., Kaneda, N., Yukimura, T., Nakatani, T., and Miura, K. Attenuation of renal fibrosis by curcumin in rat obstructive nephropathy. Urology 2006;67(2):440-446. View abstract.
Lamb, S. R. and Wilkinson, S. M. Contact allergy to tetrahydrocurcumin. Contact Dermatitis 2003;48(4):227. View abstract.
Lantz, R. C., Chen, G. J., Solyom, A. M., Jolad, S. D., and Timmermann, B. N. The effect of turmeric extracts on inflammatory mediator production. Phytomedicine. 2005;12(6-7):445-452. View abstract.
Lee, J. C., Kinniry, P. A., Arguiri, E., Serota, M., Kanterakis, S., Chatterjee, S., Solomides, C. C., Javvadi, P., Koumenis, C., Cengel, K. A., and Christofidou-Solomidou, M. Dietary curcumin increases antioxidant defenses in lung, ameliorates radiation-induced pulmonary fibrosis, and improves survival in mice. Radiat.Res 2010;173(5):590-601. View abstract.
Leite, K. R., Chade, D. C., Sanudo, A., Sakiyama, B. Y., Batocchio, G., and Srougi, M. Effects of curcumin in an orthotopic murine bladder tumor model. Int.Braz.J Urol. 2009;35(5):599-606. View abstract.
Li, H., van Berlo, D., Shi, T., Speit, G., Knaapen, A. M., Borm, P. J., Albrecht, C., and Schins, R. P. Curcumin protects against cytotoxic and inflammatory effects of quartz particles but causes oxidative DNA damage in a rat lung epithelial cell line. Toxicol Appl.Pharmacol 2-15-2008;227(1):115-124. View abstract.
Li, W. Q., Dehnade, F., and Zafarullah, M. Oncostatin M-induced matrix metalloproteinase and tissue inhibitor of metalloproteinase-3 genes expression in chondrocytes requires Janus kinase/STAT signaling pathway. J Immunol. 3-1-2001;166(5):3491-3498. View abstract.
Li, W., Wang, S., Feng, J., Xiao, Y., Xue, X., Zhang, H., Wang, Y., and Liang, X. Structure elucidation and NMR assignments for curcuminoids from the rhizomes of Curcuma longa. Magn Reson.Chem. 2009;47(10):902-908. View abstract.
Li, W., Xiao, H., Wang, L., and Liang, X. [Analysis of minor curcuminoids in Curcuma longa L. by high performance liquid chromatography-tandem mass spectrometry]. Se.Pu. 2009;27(3):264-269. View abstract.
Li, Y. C., Wang, F. M., Pan, Y., Qiang, L. Q., Cheng, G., Zhang, W. Y., and Kong, L. D. Antidepressant-like effects of curcumin on serotonergic receptor-coupled AC-cAMP pathway in chronic unpredictable mild stress of rats. Prog.Neuropsychopharmacol.Biol.Psychiatry 4-30-2009;33(3):435-449. View abstract.
Lian, Q., Li, X., Shang, Y., Yao, S., Ma, L., and Jin, S. Protective effect of curcumin on endotoxin-induced acute lung injury in rats. J Huazhong.Univ Sci.Technolog.Med.Sci. 2006;26(6):678-681. View abstract.
Liddle, M., Hull, C., Liu, C., and Powell, D. Contact urticaria from curcumin. Dermatitis 2006;17(4):196-197. View abstract.
Lim, G. P., Chu, T., Yang, F., Beech, W., Frautschy, S. A., and Cole, G. M. The curry spice curcumin reduces oxidative damage and amyloid pathology in an Alzheimer transgenic mouse. J Neurosci. 11-1-2001;21(21):8370-8377. View abstract.
Lin, R., Chen, X., Li, W., Han, Y., Liu, P., and Pi, R. Exposure to metal ions regulates mRNA levels of APP and BACE1 in PC12 cells: blockage by curcumin. Neurosci.Lett. 8-8-2008;440(3):344-347. View abstract.
Literat, A., Su, F., Norwicki, M., Durand, M., Ramanathan, R., Jones, C. A., Minoo, P., and Kwong, K. Y. Regulation of pro-inflammatory cytokine expression by curcumin in hyaline membrane disease (HMD). Life Sci. 12-7-2001;70(3):253-267. View abstract.
Madden, K., Flowers, L., Salani, R., Horowitz, I., Logan, S., Kowalski, K., Xie, J., and Mohammed, S. I. Proteomics-based approach to elucidate the mechanism of antitumor effect of curcumin in cervical cancer. Prostaglandins Leukot.Essent.Fatty Acids 2009;80(1):9-18. View abstract.
Madkor, H. R., Mansour, S. W., and Ramadan, G. Modulatory effects of garlic, ginger, turmeric and their mixture on hyperglycaemia, dyslipidaemia and oxidative stress in streptozotocin-nicotinamide diabetic rats. Br J Nutr 2011;105(8):1210-1217. View abstract.
Mahattanadul, S., Nakamura, T., Panichayupakaranant, P., Phdoongsombut, N., Tungsinmunkong, K., and Bouking, P. Comparative antiulcer effect of bisdemethoxycurcumin and curcumin in a gastric ulcer model system. Phytomedicine. 2009;16(4):342-351. View abstract.
Mahesh, T., Balasubashini, M. S., and Menon, V. P. Effect of photo-irradiated curcumin treatment against oxidative stress in streptozotocin-induced diabetic rats. J Med.Food 2005;8(2):251-255. View abstract.
Mahesh, T., Sri Balasubashini, M. M., and Menon, V. P. Photo-irradiated curcumin supplementation in streptozotocin-induced diabetic rats: effect on lipid peroxidation. Therapie 2004;59(6):639-644. View abstract.
Mani, H., Sidhu, G. S., Kumari, R., Gaddipati, J. P., Seth, P., and Maheshwari, R. K. Curcumin differentially regulates TGF-beta1, its receptors and nitric oxide synthase during impaired wound healing. Biofactors 2002;16(1-2):29-43. View abstract.
Manzan, A. C., Toniolo, F. S., Bredow, E., and Povh, N. P. Extraction of essential oil and pigments from Curcuma longa [L] by steam distillation and extraction with volatile solvents. J Agric.Food Chem. 11-5-2003;51(23):6802-6807. View abstract.
Mehta, K., Pantazis, P., McQueen, T., and Aggarwal, B. B. Antiproliferative effect of curcumin (diferuloylmethane) against human breast tumor cell lines. Anticancer Drugs 1997;8(5):470-481. View abstract.
Meja, K. K., Rajendrasozhan, S., Adenuga, D., Biswas, S. K., Sundar, I. K., Spooner, G., Marwick, J. A., Chakravarty, P., Fletcher, D., Whittaker, P., Megson, I. L., Kirkham, P. A., and Rahman, I. Curcumin restores corticosteroid function in monocytes exposed to oxidants by maintaining HDAC2. Am.J Respir.Cell Mol.Biol. 2008;39(3):312-323. View abstract.
Meselhy, M. R. Inhibition of LPS-induced NO production by the oleogum resin of Commiphora wightii and its constituents. Phytochemistry 2003;62(2):213-218. View abstract.
Mishra, R. K. and Singh, S. K. Reversible antifertility effect of aqueous rhizome extract of Curcuma longa L. in male laboratory mice. Contraception 2009;79(6):479-487. View abstract.
Moghaddam, S. J., Barta, P., Mirabolfathinejad, S. G., Ammar-Aouchiche, Z., Garza, N. T., Vo, T. T., Newman, R. A., Aggarwal, B. B., Evans, C. M., Tuvim, M. J., Lotan, R., and Dickey, B. F. Curcumin inhibits COPD-like airway inflammation and lung cancer progression in mice. Carcinogenesis 2009;30(11):1949-1956. View abstract.
Mohammadi, A., Sahebkar, A., Iranshahi, M., Amini, M., Khojasteh, R., Ghayour-Mobarhan, M., and Ferns, G. A. Effects of supplementation with curcuminoids on dyslipidemia in obese patients: a randomized crossover trial. Phytother Res 2013;27(3):374-379. View abstract.
Molnar, V. and Garai, J. Plant-derived anti-inflammatory compounds affect MIF tautomerase activity. Int.Immunopharmacol. 2005;5(5):849-856. View abstract.
Moon, D. O., Jin, C. Y., Lee, J. D., Choi, Y. H., Ahn, S. C., Lee, C. M., Jeong, S. C., Park, Y. M., and Kim, G. Y. Curcumin decreases binding of Shiga-like toxin-1B on human intestinal epithelial cell line HT29 stimulated with TNF-alpha and IL-1beta: suppression of p38, JNK and NF-kappaB p65 as potential targets. Biol.Pharm Bull. 2006;29(7):1470-1475. View abstract.
Moon, D. O., Kim, M. O., Lee, H. J., Choi, Y. H., Park, Y. M., Heo, M. S., and Kim, G. Y. Curcumin attenuates ovalbumin-induced airway inflammation by regulating nitric oxide. Biochem.Biophys.Res Commun. 10-17-2008;375(2):275-279. View abstract.
Mrudula, T., Suryanarayana, P., Srinivas, P. N., and Reddy, G. B. Effect of curcumin on hyperglycemia-induced vascular endothelial growth factor expression in streptozotocin-induced diabetic rat retina. Biochem.Biophys.Res Commun. 9-21-2007;361(2):528-532. View abstract.
Mukherjee, S., Roy, M., Dey, S., and Bhattacharya, R. K. A Mechanistic Approach for Modulation of Arsenic Toxicity in Human Lymphocytes by Curcumin, an Active Constituent of Medicinal Herb Curcuma longa Linn. J Clin Biochem.Nutr. 2007;41(1):32-42. View abstract.
Mun, S. H., Kim, H. S., Kim, J. W., Ko, N. Y., Kim, do K., Lee, B. Y., Kim, B., Won, H. S., Shin, H. S., Han, J. W., Lee, H. Y., Kim, Y. M., and Choi, W. S. Oral administration of curcumin suppresses production of matrix metalloproteinase (MMP)-1 and MMP-3 to ameliorate collagen-induced arthritis: inhibition of the PKCdelta/JNK/c-Jun pathway. J Pharmacol Sci. 2009;111(1):13-21. View abstract.
Murugan, P. and Pari, L. Influence of tetrahydrocurcumin on erythrocyte membrane bound enzymes and antioxidant status in experimental type 2 diabetic rats. J Ethnopharmacol. 9-25-2007;113(3):479-486. View abstract.
Nagabhushan, M., Amonkar, A. J., and Bhide, S. V. In vitro antimutagenicity of curcumin against environmental mutagens. Food Chem.Toxicol. 1987;25(7):545-547. View abstract.
Nakmareong, S., Kukongviriyapan, U., Pakdeechote, P., Donpunha, W., Kukongviriyapan, V., Kongyingyoes, B., Sompamit, K., and Phisalaphong, C. Antioxidant and vascular protective effects of curcumin and tetrahydrocurcumin in rats with L-NAME-induced hypertension. Naunyn Schmiedebergs Arch Pharmacol 2011;383(5):519-529. View abstract.
Nan, B., Lin, P., Lumsden, A. B., Yao, Q., and Chen, C. Effects of TNF-alpha and curcumin on the expression of thrombomodulin and endothelial protein C receptor in human endothelial cells. Thromb.Res 2005;115(5):417-426. View abstract.
Nan, B., Yang, H., Yan, S., Lin, P. H., Lumsden, A. B., Yao, Q., and Chen, C. C-reactive protein decreases expression of thrombomodulin and endothelial protein C receptor in human endothelial cells. Surgery 2005;138(2):212-222. View abstract.
Nayak, S. and Sashidhar, R. B. Metabolic intervention of aflatoxin B1 toxicity by curcumin. J Ethnopharmacol. 2-17-2010;127(3):641-644. View abstract.
Naz, R. K. Can curcumin provide an ideal contraceptive? Mol.Reprod.Dev 2011;78(2):116-123. View abstract.
Nemavarkar, P., Chourasia, B. K., and Pasupathy, K. Evaluation of radioprotective action of compounds using Saccharomyces cerevisiae. J Environ.Pathol.Toxicol Oncol. 2004;23(2):145-151. View abstract.
Nguyen, K. T., Shaikh, N., Shukla, K. P., Su, S. H., Eberhart, R. C., and Tang, L. Molecular responses of vascular smooth muscle cells and phagocytes to curcumin-eluting bioresorbable stent materials. Biomaterials 2004;25(23):5333-5346. View abstract.
O’Mahony, R., Al Khtheeri, H., Weerasekera, D., Fernando, N., Vaira, D., Holton, J., and Basset, C. Bactericidal and anti-adhesive properties of culinary and medicinal plants against Helicobacter pylori. World J Gastroenterol. 12-21-2005;11(47):7499-7507. View abstract.
Oetari, S., Sudibyo, M., Commandeur, J. N., Samhoedi, R., and Vermeulen, N. P. Effects of curcumin on cytochrome P450 and glutathione S-transferase activities in rat liver. Biochem Pharmacol 1-12-1996;51(1):39-45. View abstract.
Olszanecki, R., Gebska, A., and Korbut, R. The role of haem oxygenase-1 in the decrease of endothelial intercellular adhesion molecule-1 expression by curcumin. Basic Clin Pharmacol Toxicol 2007;101(6):411-415. View abstract.
Panahi, Y., Sahebkar, A., Amiri, M., Davoudi, S. M., Beiraghdar, F., Hoseininejad, S. L., and Kolivand, M. Improvement of sulphur mustard-induced chronic pruritus, quality of life and antioxidant status by curcumin: results of a randomised, double-blind, placebo-controlled trial. Br J Nutr 2012;108(7):1272-1279. View abstract.
Panahi, Y., Sahebkar, A., Parvin, S., and Saadat, A. A randomized controlled trial on the anti-inflammatory effects of curcumin in patients with chronic sulphur mustard-induced cutaneous complications. Ann.Clin Biochem. 2012;49(Pt 6):580-588. View abstract.
Panchatcharam, M., Miriyala, S., Gayathri, V. S., and Suguna, L. Curcumin improves wound healing by modulating collagen and decreasing reactive oxygen species. Mol.Cell Biochem. 2006;290(1-2):87-96. View abstract.
Paramasivam, S., Thangaradjou, T., and Kannan, L. Effect of natural preservatives on the growth of histamine producing bacteria. J Environ.Biol. 2007;28(2):271-274. View abstract.
Park, B. S., Kim, J. G., Kim, M. R., Lee, S. E., Takeoka, G. R., Oh, K. B., and Kim, J. H. Curcuma longa L. constituents inhibit sortase A and Staphylococcus aureus cell adhesion to fibronectin. J Agric.Food Chem. 11-16-2005;53(23):9005-9009. View abstract.
Park, C., Moon, D. O., Choi, I. W., Choi, B. T., Nam, T. J., Rhu, C. H., Kwon, T. K., Lee, W. H., Kim, G. Y., and Choi, Y. H. Curcumin induces apoptosis and inhibits prostaglandin E(2) production in synovial fibroblasts of patients with rheumatoid arthritis. Int.J Mol.Med. 2007;20(3):365-372. View abstract.
Park, E. J., Jeon, C. H., Ko, G., Kim, J., and Sohn, D. H. Protective effect of curcumin in rat liver injury induced by carbon tetrachloride. J Pharm Pharmacol 2000;52(4):437-440. View abstract.
Park, S. Y. and Kim, D. S. Discovery of natural products from Curcuma longa that protect cells from beta-amyloid insult: a drug discovery effort against Alzheimer’s disease. J Nat.Prod. 2002;65(9):1227-1231. View abstract.
Parshad, R., Sanford, K. K., Price, F. M., Steele, V. E., Tarone, R. E., Kelloff, G. J., and Boone, C. W. Protective action of plant polyphenols on radiation-induced chromatid breaks in cultured human cells. Anticancer Res 1998;18(5A):3263-3266. View abstract.
Patel, S. S., Shah, R. S., and Goyal, R. K. Antihyperglycemic, antihyperlipidemic and antioxidant effects of Dihar, a polyherbal ayurvedic formulation in streptozotocin induced diabetic rats. Indian J Exp.Biol. 2009;47(7):564-570. View abstract.
Patumraj, S., Wongeakin, N., Sridulyakul, P., Jariyapongskul, A., Futrakul, N., and Bunnag, S. Combined effects of curcumin and vitamin C to protect endothelial dysfunction in the iris tissue of STZ-induced diabetic rats. Clin Hemorheol.Microcirc. 2006;35(4):481-489. View abstract.
Pavithra, B. H., Prakash, N., and Jayakumar, K. Modification of pharmacokinetics of norfloxacin following oral administration of curcumin in rabbits. J Vet.Sci. 2009;10(4):293-297. View abstract.
Peeyush, K. T., Gireesh, G., Jobin, M., and Paulose, C. S. Neuroprotective role of curcumin in the cerebellum of streptozotocin-induced diabetic rats. Life Sci. 11-4-2009;85(19-20):704-710. View abstract.
Perez-Arriaga, L., Mendoza-Magana, M. L., Cortes-Zarate, R., Corona-Rivera, A., Bobadilla-Morales, L., Troyo-Sanroman, R., and Ramirez-Herrera, M. A. Cytotoxic effect of curcumin on Giardia lamblia trophozoites. Acta Trop. 2006;98(2):152-161. View abstract.
Peschel, D., Koerting, R., and Nass, N. Curcumin induces changes in expression of genes involved in cholesterol homeostasis. J Nutr.Biochem. 2007;18(2):113-119. View abstract.
Platel, K. and Srinivasan, K. Influence of dietary spices and their active principles on pancreatic digestive enzymes in albino rats. Nahrung 2000;44(1):42-46. View abstract.
Pongchaidecha, A., Lailerd, N., Boonprasert, W., and Chattipakorn, N. Effects of curcuminoid supplement on cardiac autonomic status in high-fat-induced obese rats. Nutrition 2009;25(7-8):870-878. View abstract.
Pungcharoenkul, K. and Thongnopnua, P. Effect of different curcuminoid supplement dosages on total in vivo antioxidant capacity and cholesterol levels of healthy human subjects. Phytother Res 2011;25(11):1721-1726. View abstract.
Punithavathi, D., Venkatesan, N., and Babu, M. Curcumin inhibition of bleomycin-induced pulmonary fibrosis in rats. Br.J Pharmacol 2000;131(2):169-172. View abstract.
Punithavathi, D., Venkatesan, N., and Babu, M. Protective effects of curcumin against amiodarone-induced pulmonary fibrosis in rats. Br.J Pharmacol 2003;139(7):1342-1350. View abstract.
Qin, N. Y., Yang, F. Q., Wang, Y. T., and Li, S. P. Quantitative determination of eight components in rhizome (Jianghuang) and tuberous root (Yujin) of Curcuma longa using pressurized liquid extraction and gas chromatography-mass spectrometry. J Pharm Biomed.Anal. 1-17-2007;43(2):486-492. View abstract.
Quiles, J. L., Mesa, M. D., Ramirez-Tortosa, C. L., Aguilera, C. M., Battino, M., Gil, A., and Ramirez-Tortosa, M. C. Curcuma longa extract supplementation reduces oxidative stress and attenuates aortic fatty streak development in rabbits. Arterioscler.Thromb.Vasc.Biol. 7-1-2002;22(7):1225-1231. View abstract.
Rafatullah, S., Tariq, M., Al Yahya, M. A., Mossa, J. S., and Ageel, A. M. Evaluation of turmeric (Curcuma longa) for gastric and duodenal antiulcer activity in rats. J Ethnopharmacol. 1990;29(1):25-34. View abstract.
Rai, D., Singh, J. K., Roy, N., and Panda, D. Curcumin inhibits FtsZ assembly: an attractive mechanism for its antibacterial activity. Biochem.J 2-15-2008;410(1):147-155. View abstract.
Ram, A., Das, M., and Ghosh, B. Curcumin attenuates allergen-induced airway hyperresponsiveness in sensitized guinea pigs. Biol.Pharm Bull. 2003;26(7):1021-1024. View abstract.
Ramaswami, G., Chai, H., Yao, Q., Lin, P. H., Lumsden, A. B., and Chen, C. Curcumin blocks homocysteine-induced endothelial dysfunction in porcine coronary arteries. J Vasc.Surg. 2004;40(6):1216-1222. View abstract.
Ramirez-Bosca, A., Soler, A., Carrion, M. A., Diaz-Alperi, J., Bernd, A., Quintanilla, C., Quintanilla, Almagro E., and Miquel, J. An hydroalcoholic extract of curcuma longa lowers the apo B/apo A ratio. Implications for atherogenesis prevention. Mech.Ageing Dev. 10-20-2000;119(1-2):41-47. View abstract.
Ramirez-Tortosa, M. C., Ramirez-Tortosa, C. L., Mesa, M. D., Granados, S., Gil, A., and Quiles, J. L. Curcumin ameliorates rabbits’s steatohepatitis via respiratory chain, oxidative stress, and TNF-alpha. Free Radic.Biol.Med. 10-1-2009;47(7):924-931. View abstract.
Ranjan, D., Siquijor, A., Johnston, T. D., Wu, G., and Nagabhuskahn, M. The effect of curcumin on human B-cell immortalization by Epstein-Barr virus. Am Surg 1998;64(1):47-51. View abstract.
Rao, C. V., Simi, B., and Reddy, B. S. Inhibition by dietary curcumin of azoxymethane-induced ornithine decarboxylase, tyrosine protein kinase, arachidonic acid metabolism and aberrant crypt foci formation in the rat colon. Carcinogenesis 1993;14(11):2219-2225. View abstract.
Rastogi, M., Ojha, R. P., Rajamanickam, G. V., Agrawal, A., Aggarwal, A., and Dubey, G. P. Curcuminoids modulates oxidative damage and mitochondrial dysfunction in diabetic rat brain. Free Radic.Res 2008;42(11-12):999-1005. View abstract.
Rasyid, A. and Lelo, A. The effect of curcumin and placebo on human gall-bladder function: an ultrasound study. Aliment.Pharmacol Ther. 1999;13(2):245-249. View abstract.
Reyes-Gordillo, K., Segovia, J., Shibayama, M., Tsutsumi, V., Vergara, P., Moreno, M. G., and Muriel, P. Curcumin prevents and reverses cirrhosis induced by bile duct obstruction or CCl4 in rats: role of TGF-beta modulation and oxidative stress. Fundam.Clin Pharmacol 2008;22(4):417-427. View abstract.
Reyes-Gordillo, K., Segovia, J., Shibayama, M., Vergara, P., Moreno, M. G., and Muriel, P. Curcumin protects against acute liver damage in the rat by inhibiting NF-kappaB, proinflammatory cytokines production and oxidative stress. Biochim.Biophys.Acta 2007;1770(6):989-996. View abstract.
Rezvani, M. and Ross, G. A. Modification of radiation-induced acute oral mucositis in the rat. Int.J Radiat.Biol. 2004;80(2):177-182. View abstract.
Rithaporn, T., Monga, M., and Rajasekaran, M. Curcumin: a potential vaginal contraceptive. Contraception 2003;68(3):219-223. View abstract.
Romero, M. R., Efferth, T., Serrano, M. A., Castano, B., Macias, R. I., Briz, O., and Marin, J. J. Effect of artemisinin/artesunate as inhibitors of hepatitis B virus production in an “in vitro” replicative system. Antiviral Res 2005;68(2):75-83. View abstract.
Rukkumani, R., Aruna, K., Varma, P. S., and Menon, V. P. Curcumin influences hepatic expression patterns of matrix metalloproteinases in liver toxicity. Ital.J Biochem. 2004;53(2):61-66. View abstract.
Sahin, Kavakli H., Koca, C., and Alici, O. Antioxidant effects of curcumin in spinal cord injury in rats. Ulus.Travma.Acil.Cerrahi.Derg. 2011;17(1):14-18. View abstract.
Salh, B. S., Assi, K., Templeman, V., Parhar, K., Owen, D., Gomez-Munoz, A., and Jacobson, K. Curcumin attenuates DNB-induced murine colitis. Am.J Physiol Gastrointest.Liver Physiol 3-13-2003; View abstract.
Satoskar, R. R., Shah, S. J., and Shenoy, S. G. Evaluation of anti-inflammatory property of curcumin (diferuloyl methane) in patients with postoperative inflammation. Int.J Clin Pharmacol Ther.Toxicol. 1986;24(12):651-654. View abstract.
Seo, K. I., Choi, M. S., Jung, U. J., Kim, H. J., Yeo, J., Jeon, S. M., and Lee, M. K. Effect of curcumin supplementation on blood glucose, plasma insulin, and glucose homeostasis related enzyme activities in diabetic db/db mice. Mol.Nutr.Food Res 2008;52(9):995-1004. View abstract.
Shahiduzzaman, M., Dyachenko, V., Khalafalla, R. E., Desouky, A. Y., and Daugschies, A. Effects of curcumin on Cryptosporidium parvum in vitro. Parasitol.Res 2009;105(4):1155-1161. View abstract.
Sharma, R. A., Euden, S. A., Platton, S. L., Cooke, D. N., Shafayat, A., Hewitt, H. R., Marczylo, T. H., Morgan, B., Hemingway, D., Plummer, S. M., Pirmohamed, M., Gescher, A. J., and Steward, W. P. Phase I clinical trial of oral curcumin: biomarkers of systemic activity and compliance. Clin Cancer Res 10-15-2004;10(20):6847-6854. View abstract.
Sharma, S., Kulkarni, S. K., Agrewala, J. N., and Chopra, K. Curcumin attenuates thermal hyperalgesia in a diabetic mouse model of neuropathic pain. Eur.J Pharmacol 5-1-2006;536(3):256-261. View abstract.
Shimmyo, Y., Kihara, T., Akaike, A., Niidome, T., and Sugimoto, H. Epigallocatechin-3-gallate and curcumin suppress amyloid beta-induced beta-site APP cleaving enzyme-1 upregulation. Neuroreport 8-27-2008;19(13):1329-1333. View abstract.
Shimouchi, A., Nose, K., Takaoka, M., Hayashi, H., and Kondo, T. Effect of dietary turmeric on breath hydrogen. Dig.Dis.Sci. 2009;54(8):1725-1729. View abstract.
Shoba, G., Joy, D., Joseph, T., Majeed, M., Rajendran, R., and Srinivas, P. S. Influence of piperine on the pharmacokinetics of curcumin in animals and human volunteers. Planta Med 1998;64(4):353-356. View abstract.
Shoskes, D. A. Effect of bioflavonoids quercetin and curcumin on ischemic renal injury: a new class of renoprotective agents. Transplantation 7-27-1998;66(2):147-152. View abstract.
Shu, J. C., He, Y. J., Lv, X., Ye, G. R., and Wang, L. X. Curcumin prevents liver fibrosis by inducing apoptosis and suppressing activation of hepatic stellate cells. J Nat.Med. 2009;63(4):415-420. View abstract.
Shubha, M. C., Reddy, R. R., and Srinivasan, K. Antilithogenic influence of dietary capsaicin and curcumin during experimental induction of cholesterol gallstone in mice. Appl Physiol Nutr Metab 2011;36(2):201-209. View abstract.
Sivalingam, N., Hanumantharaya, R., Faith, M., Basivireddy, J., Balasubramanian, K. A., and Jacob, M. Curcumin reduces indomethacin-induced damage in the rat small intestine. J Appl.Toxicol 2007;27(6):551-560. View abstract.
Smith, M. R., Gangireddy, S. R., Narala, V. R., Hogaboam, C. M., Standiford, T. J., Christensen, P. J., Kondapi, A. K., and Reddy, R. C. Curcumin inhibits fibrosis-related effects in IPF fibroblasts and in mice following bleomycin-induced lung injury. Am.J Physiol Lung Cell Mol.Physiol 1-8-2010; View abstract.
Song, E. K., Cho, H., Kim, J. S., Kim, N. Y., An, N. H., Kim, J. A., Lee, S. H., and Kim, Y. C. Diarylheptanoids with free radical scavenging and hepatoprotective activity in vitro from Curcuma longa. Planta Med. 2001;67(9):876-877. View abstract.
Soni, K. B., Rajan, A., and Kuttan, R. Reversal of aflatoxin induced liver damage by turmeric and curcumin. Cancer Lett. 9-30-1992;66(2):115-121. View abstract.
Sood, A., Mathew, R., and Trachtman, H. Cytoprotective effect of curcumin in human proximal tubule epithelial cells exposed to shiga toxin. Biochem.Biophys.Res Commun. 4-27-2001;283(1):36-41. View abstract.
Sotanaphun, U., Phattanawasin, P., and Sriphong, L. Application of Scion image software to the simultaneous determination of curcuminoids in turmeric (Curcuma longa). Phytochem.Anal. 2009;20(1):19-23. View abstract.
Sreejayan and Rao, M. N. Curcuminoids as potent inhibitors of lipid peroxidation. J Pharm Pharmacol 1994;46(12):1013-1016. View abstract.
Srinivasan K and Sambaiah K. The effect of spices on cholesterol 7 alpha-hydroxylase activity and on serum and hepatic cholesterol levels in the rat. Internat J Vit Nutr Res 1991;61:364-369.
Srinivasan, K. and Sambaiah, K. The effect of spices on cholesterol 7 alpha-hydroxylase activity and on serum and hepatic cholesterol levels in the rat. Int.J Vitam.Nutr.Res 1991;61(4):364-369. View abstract.
Srinivasan, M. Effect of curcumin on blood sugar as seen in a diabetic subject. Indian J Med Sci 1972;26(4):269-270. View abstract.
Srinivasan, M., Sudheer, A. R., Rajasekaran, K. N., and Menon, V. P. Effect of curcumin analog on gamma-radiation-induced cellular changes in primary culture of isolated rat hepatocytes in vitro. Chem.Biol.Interact. 10-22-2008;176(1):1-8. View abstract.
Srivastava, K. C. Extracts from two frequently consumed spices–cumin (Cuminum cyminum) and turmeric (Curcuma longa)–inhibit platelet aggregation and alter eicosanoid biosynthesis in human blood platelets. Prostaglandins Leukot.Essent.Fatty Acids 1989;37(1):57-64. View abstract.
Srivastava, K. C., Bordia, A., and Verma, S. K. Curcumin, a major component of food spice turmeric (Curcuma longa) inhibits aggregation and alters eicosanoid metabolism in human blood platelets. Prostaglandins Leukot.Essent.Fatty Acids 1995;52(4):223-227. View abstract.
Srivastava, R., Dikshit, M., Srimal, R. C., and Dhawan, B. N. Anti-thrombotic effect of curcumin. Thromb.Res 11-1-1985;40(3):413-417. View abstract.
Srivastava, R., Puri, V., Srimal, R. C., and Dhawan, B. N. Effect of curcumin on platelet aggregation and vascular prostacyclin synthesis. Arzneimittelforschung. 1986;36(4):715-717. View abstract.
Sugimoto, K., Hanai, H., Tozawa, K., Aoshi, T., Uchijima, M., Nagata, T., and Koide, Y. Curcumin prevents and ameliorates trinitrobenzene sulfonic acid-induced colitis in mice. Gastroenterology 2002;123(6):1912-1922. View abstract.
Sumiyoshi, M. and Kimura, Y. Effects of a turmeric extract (Curcuma longa) on chronic ultraviolet B irradiation-induced skin damage in melanin-possessing hairless mice. Phytomedicine. 2009;16(12):1137-1143. View abstract.
Suzuki, M., Betsuyaku, T., Ito, Y., Nagai, K., Odajima, N., Moriyama, C., Nasuhara, Y., and Nishimura, M. Curcumin attenuates elastase- and cigarette smoke-induced pulmonary emphysema in mice. Am.J Physiol Lung Cell Mol.Physiol 2009;296(4):L614-L623. View abstract.
Tanaka, K., Kuba, Y., Sasaki, T., Hiwatashi, F., and Komatsu, K. Quantitation of curcuminoids in curcuma rhizome by near-infrared spectroscopic analysis. J Agric.Food Chem. 10-8-2008;56(19):8787-8792. View abstract.
Tang, Y. H., Bao, M. W., Yang, B., Zhang, Y., Zhang, B. S., Zhou, Q., Chen, J. L., and Huang, C. X. [Curcumin attenuates left ventricular dysfunction and remodeling in rabbits with chronic heart failure.]. Zhonghua Xin.Xue.Guan.Bing.Za Zhi. 2009;37(3):262-267. View abstract.
Tanwar, V., Sachdeva, J., Golechha, M., Kumari, S., and Arya, D. S. Curcumin protects rat myocardium against isoproterenol-induced ischemic injury: attenuation of ventricular dysfunction through increased expression of Hsp27 along with strengthening antioxidant defense system. J Cardiovasc.Pharmacol 2010;55(4):377-384. View abstract.
Tanwar, V., Sachdeva, J., Kishore, K., Mittal, R., Nag, T. C., Ray, R., Kumari, S., and Arya, D. S. Dose-dependent actions of curcumin in experimentally induced myocardial necrosis: a biochemical, histopathological, and electron microscopic evidence. Cell Biochem.Funct. 2010;28(1):74-82. View abstract.
Tayel, A. A. and El Tras, W. F. Possibility of fighting food borne bacteria by egyptian folk medicinal herbs and spices extracts. J Egypt.Public Health Assoc. 2009;84(1-2):21-32. View abstract.
Teichmann, A., Heuschkel, S., Jacobi, U., Presse, G., Neubert, R. H., Sterry, W., and Lademann, J. Comparison of stratum corneum penetration and localization of a lipophilic model drug applied in an o/w microemulsion and an amphiphilic cream. Eur.J Pharm Biopharm. 2007;67(3):699-706. View abstract.
Thompson, D. A. and Tan, B. B. Tetrahydracurcumin-related allergic contact dermatitis. Contact Dermatitis 2006;55(4):254-255. View abstract.
Thongson, C., Davidson, P. M., Mahakarnchanakul, W., and Vibulsresth, P. Antimicrobial effect of Thai spices against Listeria monocytogenes and Salmonella typhimurium DT104. J Food Prot. 2005;68(10):2054-2058. View abstract.
Thresiamma, K. C., George, J., and Kuttan, R. Protective effect of curcumin, ellagic acid and bixin on radiation induced genotoxicity. J Exp.Clin Cancer Res 1998;17(4):431-434. View abstract.
Tian, Y. M., Zhou, D., Zhang, W., and Cheng, C. G. [Comparison and correlative analysis of trace elements in five kinds of radix curcumae]. Guang.Pu.Xue.Yu Guang.Pu.Fen.Xi. 2008;28(9):2192-2195. View abstract.
Tikoo, K., Meena, R. L., Kabra, D. G., and Gaikwad, A. B. Change in post-translational modifications of histone H3, heat-shock protein-27 and MAP kinase p38 expression by curcumin in streptozotocin-induced type I diabetic nephropathy. Br.J Pharmacol 2008;153(6):1225-1231. View abstract.
Tirkey, N., Kaur, G., Vij, G., and Chopra, K. Curcumin, a diferuloylmethane, attenuates cyclosporine-induced renal dysfunction and oxidative stress in rat kidneys. BMC.Pharmacol 2005;5:15. View abstract.
Ukil, A., Maity, S., Karmakar, S., Datta, N., Vedasiromoni, J. R., and Das, P. K. Curcumin, the major component of food flavour turmeric, reduces mucosal injury in trinitrobenzene sulphonic acid-induced colitis. Br.J Pharmacol 2003;139(2):209-218. View abstract.
Usharani, P., Mateen, A. A., Naidu, M. U., Raju, Y. S., and Chandra, N. Effect of NCB-02, atorvastatin and placebo on endothelial function, oxidative stress and inflammatory markers in patients with type 2 diabetes mellitus: a randomized, parallel-group, placebo-controlled, 8-week study. Drugs R.D. 2008;9(4):243-250. View abstract.
Van Dau N, Ngoc Ham N, Huy Khac D, and et al. The effects of a traditional drug, tumeric (Curcuma longa), and placebo on the healing of duodenal ulcer. Phytomed 1998;5(1):29-34.
Vareed, S. K., Kakarala, M., Ruffin, M. T., Crowell, J. A., Normolle, D. P., Djuric, Z., and Brenner, D. E. Pharmacokinetics of curcumin conjugate metabolites in healthy human subjects. Cancer Epidemiol.Biomarkers Prev. 2008;17(6):1411-1417. View abstract.
Varghese, K., Molnar, P., Das, M., Bhargava, N., Lambert, S., Kindy, M. S., and Hickman, J. J. A new target for amyloid beta toxicity validated by standard and high-throughput electrophysiology. PLoS.One. 2010;5(1):e8643. View abstract.
Verma S, Salamone E, and Goldin B. Curcumin and genistein, plant natural products, show synergistic inhibitory effects on the growth of human breast cancer MCF-7 cells induced by estrogenic pesticides. Biochem.Biophys.Res Commun. 4-28-1997;233(3):692-696. View abstract.
Vitaglione, P., Barone, Lumaga R., Ferracane, R., Radetsky, I., Mennella, I., Schettino, R., Koder, S., Shimoni, E., and Fogliano, V. Curcumin bioavailability from enriched bread: the effect of microencapsulated ingredients. J Agric.Food Chem 4-4-2012;60(13):3357-3366. View abstract.
Vizzutti, F., Provenzano, A., Galastri, S., Milani, S., Delogu, W., Novo, E., Caligiuri, A., Zamara, E., Arena, U., Laffi, G., Parola, M., Pinzani, M., and Marra, F. Curcumin limits the fibrogenic evolution of experimental steatohepatitis. Lab Invest 2010;90(1):104-115. View abstract.
Voznesens’ka, T. I., Bryzhina, T. M., Sukhina, V. S., Makohon, N. V., and Aleksieieva, I. M. [Effect of NF-kappaB activation inhibitor curcumin on the oogenesis and follicular cell death in immune ovarian failure in mice]. Fiziol.Zh. 2010;56(4):96-101. View abstract.
Waghmare, P. F., Chaudhari, A. U., Karhadkar, V. M., and Jamkhande, A. S. Comparative evaluation of turmeric and chlorhexidine gluconate mouthwash in prevention of plaque formation and gingivitis: a clinical and microbiological study. J Contemp.Dent Pract. 2011;12(4):221-224. View abstract.
Wan, X. H., Li, Y. W., and Luo, X. P. [Curcumin attenuated the lipid peroxidation and apoptotic liver injury in copper-overloaded rats]. Zhonghua Er.Ke.Za Zhi. 2007;45(8):604-608. View abstract.
Wang, B. M., Zhai, C. Y., Fang, W. L., Chen, X., Jiang, K., and Wang, Y. M. [The inhibitory effect of curcumin on the proliferation of HT-29 colonic cancer cell induced by deoxycholic acid]. Zhonghua Nei Ke.Za Zhi. 2009;48(9):760-763. View abstract.
Wang, L. Y., Zhang, M., Zhang, C. F., and Wang, Z. T. Alkaloid and sesquiterpenes from the root tuber of Curcuma longa. Yao Xue.Xue.Bao. 2008;43(7):724-727. View abstract.
Wang, Y., Lu, Z., Wu, H., and Lv, F. Study on the antibiotic activity of microcapsule curcumin against foodborne pathogens. Int.J Food Microbiol. 11-30-2009;136(1):71-74. View abstract.
Wei, S. M., Yan, Z. Z., and Zhou, J. Curcumin attenuates ischemia-reperfusion injury in rat testis. Fertil.Steril. 2009;91(1):271-277. View abstract.
Weisberg, S. P., Leibel, R., and Tortoriello, D. V. Dietary curcumin significantly improves obesity-associated inflammation and diabetes in mouse models of diabesity. Endocrinology 2008;149(7):3549-3558. View abstract.
Wessler, S., Muenzner, P., Meyer, T. F., and Naumann, M. The anti-inflammatory compound curcumin inhibits Neisseria gonorrhoeae-induced NF-kappaB signaling, release of pro-inflammatory cytokines/chemokines and attenuates adhesion in late infection. Biol.Chem. 2005;386(5):481-490. View abstract.
Wichitnithad, W., Jongaroonngamsang, N., Pummangura, S., and Rojsitthisak, P. A simple isocratic HPLC method for the simultaneous determination of curcuminoids in commercial turmeric extracts. Phytochem.Anal. 2009;20(4):314-319. View abstract.
Wongcharoen, W., Jai-Aue, S., Phrommintikul, A., Nawarawong, W., Woragidpoonpol, S., Tepsuwan, T., Sukonthasarn, A., Apaijai, N., and Chattipakorn, N. Effects of curcuminoids on frequency of acute myocardial infarction after coronary artery bypass grafting. Am J Cardiol 7-1-2012;110(1):40-44. View abstract.
Wu, J. C., Lai, C. S., Badmaev, V., Nagabhushanam, K., Ho, C. T., and Pan, M. H. Tetrahydrocurcumin, a major metabolite of curcumin, induced autophagic cell death through coordinative modulation of PI3K/Akt-mTOR and MAPK signaling pathways in human leukemia HL-60 cells. Mol.Nutr Food Res 2011;55(11):1646-1654. View abstract.
Xu, P. H., Long, Y., Dai, F., and Liu, Z. L. The relaxant effect of curcumin on porcine coronary arterial ring segments. Vascul.Pharmacol 2007;47(1):25-30. View abstract.
Xu, Y., Ku, B. S., Yao, H. Y., Lin, Y. H., Ma, X., Zhang, Y. H., and Li, X. J. Antidepressant effects of curcumin in the forced swim test and olfactory bulbectomy models of depression in rats. Pharmacol Biochem.Behav. 2005;82(1):200-206. View abstract.
Xu, Y., Ku, B. S., Yao, H. Y., Lin, Y. H., Ma, X., Zhang, Y. H., and Li, X. J. The effects of curcumin on depressive-like behaviors in mice. Eur.J Pharmacol 7-25-2005;518(1):40-46. View abstract.
Yan, Y. D., Kim, D. H., Sung, J. H., Yong, C. S., and Choi, H. G. Enhanced oral bioavailability of docetaxel in rats by four consecutive days of pre-treatment with curcumin. Int J Pharm 10-31-2010;399(1-2):116-120. View abstract.
Yang, X., Thomas, D. P., Zhang, X., Culver, B. W., Alexander, B. M., Murdoch, W. J., Rao, M. N., Tulis, D. A., Ren, J., and Sreejayan, N. Curcumin inhibits platelet-derived growth factor-stimulated vascular smooth muscle cell function and injury-induced neointima formation. Arterioscler.Thromb.Vasc.Biol. 2006;26(1):85-90. View abstract.
Yano, Y., Satomi, M., and Oikawa, H. Antimicrobial effect of spices and herbs on Vibrio parahaemolyticus. Int.J Food Microbiol. 8-15-2006;111(1):6-11. View abstract.
Yao, J., Zhang, Q., Min, J., He, J., and Yu, Z. Novel enoyl-ACP reductase (FabI) potential inhibitors of Escherichia coli from Chinese medicine monomers. Bioorg.Med.Chem.Lett. 1-1-2010;20(1):56-59. View abstract.
Yao, Q. H., Wang, D. Q., Cui, C. C., Yuan, Z. Y., Chen, S. B., Yao, X. W., Wang, J. K., and Lian, J. F. Curcumin ameliorates left ventricular function in rabbits with pressure overload: inhibition of the remodeling of the left ventricular collagen network associated with suppression of myocardial tumor necrosis factor-alpha and matrix metalloproteinase-2 expression. Biol.Pharm Bull. 2004;27(2):198-202. View abstract.
Yeh, C. H., Chen, T. P., Wu, Y. C., Lin, Y. M., and Jing, Lin P. Inhibition of NFkappaB activation with curcumin attenuates plasma inflammatory cytokines surge and cardiomyocytic apoptosis following cardiac ischemia/reperfusion. J Surg.Res 5-1-2005;125(1):109-116. View abstract.
Yeh, C. H., Lin, Y. M., Wu, Y. C., and Lin, P. J. Inhibition of NF-kappa B activation can attenuate ischemia/reperfusion-induced contractility impairment via decreasing cardiomyocytic proinflammatory gene up-regulation and matrix metalloproteinase expression. J Cardiovasc.Pharmacol 2005;45(4):301-309. View abstract.
Yeon, K. Y., Kim, S. A., Kim, Y. H., Lee, M. K., Ahn, D. K., Kim, H. J., Kim, J. S., Jung, S. J., and Oh, S. B. Curcumin produces an antihyperalgesic effect via antagonism of TRPV1. J Dent.Res 2010;89(2):170-174. View abstract.
Yiu, W. F., Kwan, P. L., Wong, C. Y., Kam, T. S., Chiu, S. M., Chan, S. W., and Chan, R. Attenuation of fatty liver and prevention of hypercholesterolemia by extract of Curcuma longa through regulating the expression of CYP7A1, LDL-receptor, HO-1, and HMG-CoA reductase. J Food Sci 2011;76(3):H80-H89. View abstract.
Yu, Y. M. and Lin, H. C. Curcumin prevents human aortic smooth muscle cells migration by inhibiting of MMP-9 expression. Nutr.Metab Cardiovasc.Dis. 2010;20(2):125-132. View abstract.
Yu, Y., Hu, S. K., and Yan, H. [The study of insulin resistance and leptin resistance on the model of simplicity obesity rats by curcumin]. Zhonghua Yu Fang Yi.Xue.Za Zhi. 2008;42(11):818-822. View abstract.
Yu, Z. F., Kong, L. D., and Chen, Y. Antidepressant activity of aqueous extracts of Curcuma longa in mice. J Ethnopharmacol. 2002;83(1-2):161-165. View abstract.
Yuan, H. Y., Kuang, S. Y., Zheng, X., Ling, H. Y., Yang, Y. B., Yan, P. K., Li, K., and Liao, D. F. Curcumin inhibits cellular cholesterol accumulation by regulating SREBP-1/caveolin-1 signaling pathway in vascular smooth muscle cells. Acta Pharmacol Sin. 2008;29(5):555-563. View abstract.
Yuan, K., Weng, Q., Zhang, H., Xiong, J., and Xu, G. Application of capillary zone electrophoresis in the separation and determination of the curcuminoids in urine. J Pharm Biomed.Anal. 6-1-2005;38(1):133-138. View abstract.
Yuan, K., Weng, Q., Zhang, H., Xiong, J., Yang, J., and Xu, G. [Determination of curcumin in urine by capillary electrophoresis]. Se.Pu. 2004;22(6):609-612. View abstract.
Yun, S. S., Kim, S. P., Kang, M. Y., and Nam, S. H. Inhibitory effect of curcumin on liver injury in a murine model of endotoxemic shock. Biotechnol.Lett. 2010;32(2):209-214. View abstract.
Zahid, Ashraf M., Hussain, M. E., and Fahim, M. Antiatherosclerotic effects of dietary supplementations of garlic and turmeric: Restoration of endothelial function in rats. Life Sci. 7-8-2005;77(8):837-857. View abstract.
Zeng, Y., Qiu, F., Takahashi, K., Liang, J., Qu, G., and Yao, X. New sesquiterpenes and calebin derivatives from Curcuma longa. Chem.Pharm Bull.(Tokyo) 2007;55(6):940-943. View abstract.
Zhang, D. P., Qiu, H., Zhuang, Y., and Meng, F. Q. [The effect of curcumin on bleomycin-induced pulmonary fibrosis in rats]. Zhonghua Jie.He.He.Hu Xi.Za Zhi. 2007;30(3):197-201. View abstract.
Zhang, J., Jinnai, S., Ikeda, R., Wada, M., Hayashida, S., and Nakashima, K. A simple HPLC-fluorescence method for quantitation of curcuminoids and its application to turmeric products. Anal.Sci. 2009;25(3):385-388. View abstract.
Zhang, L., Fiala, M., Cashman, J., Sayre, J., Espinosa, A., Mahanian, M., Zaghi, J., Badmaev, V., Graves, M. C., Bernard, G., and Rosenthal, M. Curcuminoids enhance amyloid-beta uptake by macrophages of Alzheimer’s disease patients. J Alzheimers.Dis. 2006;10(1):1-7. View abstract.
Zhang, M., Deng, C., Zheng, J., Xia, J., and Sheng, D. Curcumin inhibits trinitrobenzene sulphonic acid-induced colitis in rats by activation of peroxisome proliferator-activated receptor gamma. Int.Immunopharmacol. 2006;6(8):1233-1242. View abstract.
Zhang, W., Liu, D., Wo, X., Zhang, Y., Jin, M., and Ding, Z. Effects of Curcuma Longa on proliferation of cultured bovine smooth muscle cells and on expression of low density lipoprotein receptor in cells. Chin Med.J (Engl) 1999;112(4):308-311. View abstract.
Zhou, G., Wang, J. F., Niu, J. Z., Lu, Y. S., Chen, W. T., Li, Z. H., and Lin, T. X. [Experimental study on protective effects of curcumin on exaggerated extracellular matrix accumulation of pulmonary fibrosis rats]. Zhongguo Zhong.Yao Za Zhi. 2006;31(7):570-573. View abstract.
Abidi A, Gupta S, Agarwal M, Bhalla HL, Saluja M. Evaluation of Efficacy of Curcumin as an Add-on therapy in Patients of Bronchial Asthma. J Clin Diagn Res. 2014;8(8):HC19-24. View abstract.
Ahmadi R, Salari S, Sharifi MD, et al. Oral nano-curcumin formulation efficacy in the management of mild to moderate outpatient COVID-19: A randomized triple-blind placebo-controlled clinical trial. Food Sci Nutr 2021;9(8):4068-4075. View abstract.
Al-Karawi D, Al Mamoori DA, Tayyar Y. The role of curcumin administration in patients with major depressive disorder: Mini meta-analysis of clinical trials. Phytother Res. 2016;30(2):175-83. View abstract.
Al-Maweri SA, Alhajj MN, Deshisha EA, et al. Curcumin mouthwashes versus chlorhexidine in controlling plaque and gingivitis: A systematic review and meta-analysis. Int J Dent Hyg. 2021. View abstract.
Alam MA, Bin Jardan YA, Raish M, Al-Mohizea AM, Ahad A, Al-Jenoobi FI. Herb-drug interaction: Pharmacokinetics and pharmacodynamics of anti-hypertensive drug amlodipine besylate in presence of lepidium sativum and curcuma longa. Xenobiotica 2022;1-9. View abstract.
Allegri P, Rosa R, Masala A, et al. Clinical effectiveness of a new oral curcumin formulation in acute non-infectious uveitic macular edema: a 12-month observational study. Eur Rev Med Pharmacol Sci 2022;26(1):46-53. View abstract.
Allen, S. W., Mueller, L., Williams, S. N., Quattrochi, L. C., and Raucy, J. The use of a high-volume screening procedure to assess the effects of dietary flavonoids on human cyp1a1 expression. Drug Metab Dispos. 2001;29(8):1074-1079. View abstract.
Altobelli E, Angeletti PM, Marziliano C, Mastrodomenico M, Giuliani AR, Petrocelli R. Potential therapeutic effects of curcumin on glycemic and lipid profile in uncomplicated type 2 diabetes – a meta-analysis of randomized controlled trial. Nutrients 2021;13(2):404. doi: 10.3390/nu13020404. View abstract.
Amalraj A, Varma K, Jacob J, et al. A novel highly bioavailable curcumin formulation improves symptoms and diagnostic indicators in rheumatoid arthritis patients: A randomized, double-blind, placebo-controlled, two-dose, three-arm, and parallel-group study. J Med Food. 2017;20(10):1022-1030. View abstract.
Amin F, Islam N, Anila N, Gilani AH. Clinical efficacy of the co-administration of Turmeric and Black seeds (Kalongi) in metabolic syndrome – a double blind randomized controlled trial – TAK-MetS trial. Complement Ther Med. 2015;23(2):165-74. View abstract.
Ampasavate, C., Sotanaphun, U., Phattanawasin, P., and Piyapolrungroj, N. Effects of Curcuma spp. on P-glycoprotein function. Phytomedicine. 2010;17(7):506-512. View abstract.
Antony B, Kizhakedath R Benny M Kuruvilla BT. Clinical Evaluation of a herbal product (Rhulief) in the management of knee osteoarthritis. Abstract 316. Osteoarthritis Cartilage 2011;19(S1):S145-S146.
Antony S, Kuttan R, Kuttan G. Immunomodulatory activity of curcumin. Immunol Invest 1999;28:291-303.. View abstract.
Appiah-Opong, R., Commandeur, J. N., Vugt-Lussenburg, B., and Vermeulen, N. P. Inhibition of human recombinant cytochrome P450s by curcumin and curcumin decomposition products. Toxicology 6-3-2007;235(1-2):83-91. View abstract.
Arabnezhad L, Mohammadifard M, Rahmani L, Majidi Z, Ferns GA, Bahrami A. Effects of curcumin supplementation on vitamin D levels in women with premenstrual syndrome and dysmenorrhea: a randomized controlled study. BMC Complement Med Ther 2022;22(1):19. View abstract.
Araujo CC, Leon LL. Biological activities of Curcuma longa L. Mem Inst Oswaldo Cruz 2001;96:723-8. View abstract.
Asadirad A, Nashibi R, Khodadadi A, et al. Antiinflammatory potential of nano-curcumin as an alternative therapeutic agent for the treatment of mild-to-moderate hospitalized COVID-19 patients in a placebo-controlled clinical trial. Phytother Res 2022;36(2):1023-1031. View abstract.
Ashtary-Larky D, Rezaei Kelishadi M, Bagheri R, et al. The Effects of Nano-Curcumin Supplementation on Risk Factors for Cardiovascular Disease: A GRADE-Assessed Systematic Review and Meta-Analysis of Clinical Trials. Antioxidants (Basel) 2021;10(7):1015. View abstract.
Bahraini P, Rajabi M, Mansouri P, Sarafian G, Chalangari R, Azizian Z. Turmeric tone as a treatment in scalp psoriasis: a randomized placebo-control clinical trial. J Cosmet Dermatol. 2018 Jun;17(3):461-466. View abstract.
Bateni Z, Rahimi HR, Hedayati M, Afsharian S, Goudarzi R, Sohrab G. The effects of nano-curcumin supplementation on glycemic control, blood pressure, lipid profile, and insulin resistance in patients with the metabolic syndrome: A randomized, double-blind clinical trial. Phytother Res. 2021;35(7):3945-3953. View abstract.
Baum L, Lam CW, Cheung SK, et al. Six-month randomized, placebo-controlled, double-blind, pilot clinical trial of curcumin in patients with Alzheimer disease (letter). J Clin Psychopharmacol 2008;28:110-3. View abstract.
Belcaro G, Cesarone MR, Dugall M, et al. Efficacy and safety of Meriva, a curcumin-phosphatidylcholine complex, during extended administration in osteoarthritis patients. Alt Med Rev 2010:15:337-4. View abstract.
Belcaro G, Dugall M, Luzzi R, et al. Phytoproflex: supplementary management of osteoarthritis: a supplement registry. Minerva Med. 2018 Apr;109(2):88-94. View abstract.
Benny, M and Antony B. Bioavailability of Biocurcumax (BCM – 095). Spice India 2006;11-15.
Burgos-Morón E, Calderón-Montaño JM, Salvador J, Robles A, López-Lázaro M. The dark side of curcumin. Int J Cancer. 2010;126(7):1771-5. View abstract.
Calaf GM, Echiburú-Chau C, Wen G, Balajee AS, Roy D. Effect of curcumin on irradiated and estrogen-transformed human breast cell lines. Int J Oncol. 2012;40(2):436-42. View abstract.
Calderón-Pérez L, Llaurad E, Companys J, et al. Acute effects of turmeric extracts on knee joint pain: a pilot, randomized controlled trial. J Med Food. 2020. doi: 10.1089/jmf.2020.0074. Online ahead of print. View abstract.
Carroll RE, Benya RV, Turgeon DK, et al. Phase IIa clinical trial of curcumin for the prevention of colorectal neoplasia. Cancer Prev Res (Phila) 2011;4:354-64. View abstract.
Chand S, Hair C, Beswick L. A rare case of turmeric-induced hepatotoxicity. Intern Med J. 2020;50(2):258-259. View abstract.
Chandran B, Goel A. A randomized, pilot study to assess the efficacy and safety of curcumin in patients with active rheumatoid arthritis. Phytother Res 2012;26:1719-25. View abstract.
Chien YJ, Chang CY, Wu MY, Chen CH, Horng YS, Wu HC. Effects of curcumin on glycemic control and lipid profile in polycystic ovary syndrome: Systematic review with meta-analysis and trial sequential analysis. Nutrients. 2021;13(2):684. View abstract.
Choi, B. H., Kim, C. G., Lim, Y., Shin, S. Y., and Lee, Y. H. Curcumin down-regulates the multidrug-resistance mdr1b gene by inhibiting the PI3K/Akt/NF kappa B pathway. Cancer Lett. 1-18-2008;259(1):111-118. View abstract.
Conrozier T, Mathieu P, Bonjean M, Marc JF, Renevier JL, Balblanc JC. A complex of three natural anti-inflammatory agents provides relief of osteoarthritis pain. Altern Ther Health Med 2014 Winter;20 Suppl 1:32-7. View abstract.
Cruz-Correa M, Hylind LM, Marrero JH, et al. Efficacy and safety of curcumin in treatment of intestinal adenomas in patients with familial adenomatous polyposis. Gastroenterology. 2018 May 23. Pii:S0016-5085(18)34564-5. [Epub ahead of print] View abstract.
Daveluy A, Géniaux H, Thibaud L, Mallaret M, Miremont-Salamé G, Haramburu F. Probable interaction between an oral vitamin K antagonist and turmeric (Curcuma longa). Therapie. 2014 Nov-Dec;69(6):519-20. View abstract.
Deeb D, Xu YX, Jiang H, et al. Curcumin (diferuloyl-methane) enhances tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in LNCaP prostate cancer cells. Mol Cancer Ther 2003;2:95-103.. View abstract.
Deodhar SD, Sethi R, Srimal RC. Preliminary study on antirheumatic activity of curcumin (diferuloyl methane). Indian J Med Res 1980;71:632-4. View abstract.
Donovan EK, Kekes-Szabo S, Lin JC, et al. A placebo-controlled, pseudo-randomized, crossover trial of botanical agents for gulf war illness: Curcumin (Curcuma longa), boswellia (Boswellia serrata), and French maritime pine bark (Pinus pinaster). Int J Environ Res Public Health. 2021;18(5):2468. View abstract.
Ebrahimzadeh A, Abbasi F, Ebrahimzadeh A, Jibril AT, Milajerdi A. Effects of curcumin supplementation on inflammatory biomarkers in patients with Rheumatoid Arthritis and Ulcerative colitis: A systematic review and meta-analysis. Complement Ther Med 2021;61:102773. View abstract.
Elyasi S, Rasta S, Taghizadeh-Kermani A, Hosseini S. Topical henna and curcumin (Alpha®) ointment efficacy for prevention of capecitabine induced hand-foot syndrome: A randomized, triple-blinded, placebo-controlled clinical. Daru 2022;30(1):117-125. View abstract.
Fetrow CW, Avila JR. Professional’s Handbook of Complementary & Alternative Medicines. 1st ed. Springhouse, PA: Springhouse Corp., 1999.
Fung FY, Wong WH, Ang SK, et al. A randomized, double-blind, placebo- controlled study on the anti-haemostatic effects of Curcuma longa, Angelica sinensis and Panax ginseng. Phytomedicine. 2017;32:88-96. View abstract.
Gammoudi R, Ameur K, Ouni B, et al. Fixed drug eruption to Serenoa repens: first case report and consideration of the use of herbal medicine. Dermatol Ther 2020 Aug 29:e14247. View abstract.
Ganta, S., Devalapally, H., and Amiji, M. Curcumin enhances oral bioavailability and anti-tumor therapeutic efficacy of paclitaxel upon administration in nanoemulsion formulation. J Pharm Sci 2010;99(11):4630-4641. View abstract.
Ghaffari A, Rafraf M, Navekar R, Sepehri B, Asghari-Jafarabadi M, Ghavami SM. Turmeric and chicory seed have beneficial effects on obesity markers and lipid profile in non-alcoholic fatty liver disease (NAFLD). Int J Vitam Nutr Res 2019;89(5-6):293-302. doi: 10.1024/0300-9831/a000568. View abstract.
Goodarzi R, Sabzian K, Shishehbor F, Mansoori A. Does turmeric/curcumin supplementation improve serum alanine aminotransferase and aspartate aminotransferase levels in patients with nonalcoholic fatty liver disease? A systematic review and meta-analysis of randomized controlled trials. Phytother Res. 2019;33(3):561-570. View abstract.
Gorabi AM, Abbasifard M, Imani D, et al. Effect of curcumin on C-reactive protein as a biomarker of systemic inflammation: An updated meta-analysis of randomized controlled trials. Phytother Res 2021. View abstract.
Grammatikopoulou MG, Gkiouras K, Theodoridis X, Asteriou E, Forbes A, Bogdanos DP. Oral Adjuvant Curcumin Therapy for Attaining Clinical Remission in Ulcerative Colitis: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Nutrients. 2018;10(11). pii: E1737. View abstract.
Gupta SC, Patchva S, Aggarwal BB. Therapeutic roles of curcumin: lessons learned from clinical trials. AAPS J. 2013;15(1):195-218. View abstract.
Haines SR, McCann MJ, Grosvenor AJ, Thomas A, Noble A, Clerens S. ACE inhibitory peptides in standard and fermented deer velvet: an in silico and in vitro investigation. BMC Complement Altern Med. 2019 Dec 5;19(1):350. View abstract.
Hallajzadeh J, Milajerdi A, Kolahdooz F, Amirani E, Mirzaei H, Asemi Z. The effects of curcumin supplementation on endothelial function: A systematic review and meta-analysis of randomized controlled trials. Phytother Res 2019;33(11):2989-95. doi: 10.1002/ptr.6477. View abstract.
Haroyan A, Mukuchyan V, Mkrtchyan N, et al. Efficacy and safety of curcumin and its combination with boswellic acid in osteoarthritis: a comparative, randomized, double-blind, placebo-controlled study. BMC Complement Altern Med. 2018;18(1):7. View abstract.
Hashemzadeh K, Davoudian N, Jaafari MR, Mirfeizi Z. The effect of nanocurcumin on the improvement symptoms of knee osteoarthritis: a randomized clinical trial. Curr Rheumatol Rev 2019 Dec 23. doi: 10.2174/1874471013666191223152658. [Epub ahead of print]. View abstract.
Hata M, Sasaki E, Ota M, et al . Allergic contact dermatitis from curcumin (turmeric). Contact Dermatitis 1997;36:107-8. View abstract.
Heshmati J, Moini A, Sepidarkish M, et al. Effects of curcumin supplementation on blood glucose, insulin resistance and androgens in patients with polycystic ovary syndrome: A randomized double-blind placebo-controlled clinical trial. Phytomedicine 2021 Jan;80:153395. doi: 10.1016/j.phymed.2020.153395. View abstract.
Holland, M. L., Panetta, J. A., Hoskins, J. M., Bebawy, M., Roufogalis, B. D., Allen, J. D., and Arnold, J. C. The effects of cannabinoids on P-glycoprotein transport and expression in multidrug resistant cells. Biochem.Pharmacol 4-14-2006;71(8):1146-1154. View abstract.
Hou, X. L., Takahashi, K., Kinoshita, N., Qiu, F., Tanaka, K., Komatsu, K., Takahashi, K., and Azuma, J. Possible inhibitory mechanism of Curcuma drugs on CYP3A4 in 1alpha,25 dihydroxyvitamin D3 treated Caco-2 cells. Int.J Pharm 6-7-2007;337(1-2):169-177. View abstract.
Hou, X. L., Takahashi, K., Tanaka, K., Tougou, K., Qiu, F., Komatsu, K., Takahashi, K., and Azuma, J. Curcuma drugs and curcumin regulate the expression and function of P-gp in Caco-2 cells in completely opposite ways. Int.J Pharm 6-24-2008;358(1-2):224-229. View abstract.
Hsiao AF, Lien YC, Tzeng IS, Liu CT, Chou SH, Horng YS. The efficacy of high- and low-dose curcumin in knee osteoarthritis: A systematic review and meta-analysis. Complement Ther Med 2021;63:102775. View abstract.
Hussaarts KGAM, Hurkmans DP, Oomen-de Hoop E, et al. Impact of curcumin (with or without piperine) on the pharmacokinetics of tamoxifen. Cancers (Basel). 2019;11(3):403. View abstract.
Imam Z, Khasawneh M, Jomaa D, Iftikhar H, Sayedahmad Z. Drug induced liver injury attributed to a curcumin supplement. Case Rep Gastrointest Med 2019 Oct 20;2019:6029403. doi: 10.1155/2019/6029403. View abstract.
Jamali N, Adib-Hajbaghery M, Soleimani A. The effect of curcumin ointment on knee pain in older adults with osteoarthritis: a randomized placebo trial. BMC Complement Med Ther 2020;20(1):305. View abstract.
Jiang N, Zhang M, Meng X, Sun B. Effects of Curcumin on the Pharmacokinetics of Amlodipine in Rats and Its Potential Mechanism. Pharm Biol. 2020;58(1):465-468. View abstract.
Jiao, Y., Wilkinson, J., Christine, Pietsch E., Buss, J. L., Wang, W., Planalp, R., Torti, F. M., and Torti, S. V. Iron chelation in the biological activity of curcumin. Free Radic.Biol.Med. 4-1-2006;40(7):1152-1160. View abstract.
Jiao, Y., Wilkinson, J., Di, X., Wang, W., Hatcher, H., Kock, N. D., D’Agostino, R., Jr., Knovich, M. A., Torti, F. M., and Torti, S. V. Curcumin, a cancer chemopreventive and chemotherapeutic agent, is a biologically active iron chelator. Blood 1-8-2009;113(2):462-469. View abstract.
Jie Z, Chao M, Jun A, Wei S, LiFeng M. Effect of curcumin on diabetic kidney disease: A systematic review and meta-analysis of randomized, double-blind, placebo-controlled clinical trials. Evid Based Complement Alternat Med 2021;2021:6109406. View abstract.
Junyaprasert, V. B., Soonthornchareonnon, N., Thongpraditchote, S., Murakami, T., and Takano, M. Inhibitory effect of Thai plant extracts on P-glycoprotein mediated efflux. Phytother.Res 2006;20(1):79-81. View abstract.
Kalluru H, Mallayasamy SR, Kondaveeti SS, Chandrasekhar V, Kalachaveedu M. Effect of turmeric supplementation on the pharmacokinetics of paclitaxel in breast cancer patients: A study with population pharmacokinetics approach. Phytother Res 2022;36(4):1761-1769. View abstract.
Kang SC, Lee CM, Choi H, et al. Evaluation of oriental medicinal herbs for estrogenic and antiproliferative activities. Phytother Res. 2006;20(11):1017-9. View abstract.
Karandish M, Mozaffari-Khosravi H, Mohammadi SM, Cheraghian B, Azhdari M. The effect of curcumin and zinc co-supplementation on glycemic parameters in overweight or obese prediabetic subjects: A phase 2 randomized, placebo-controlled trial with a multi-arm, parallel-group design. Phytother Res. 2021;35(8):4377-4387. View abstract.
Karlapudi V, Prasad Mungara AVV, Sengupta K, Davis BA, Rachaudhuri SP. A placebo-controlled double-blind study demonstrates the clinical efficacy of a novel herbal formulation for relieving joint discomfort in human subjects with osteoarthritis of knee. J Med Food. 2018 May;21(5):511-520. View abstract.
Khayat S, Fanaei H, Kherikhah M, Moghadam ZB, Kasaeian A, Javadimehr M. Curcumin attenuates severity of premenstrual syndrome symptoms: a randomized, double-blind, placebo-controlled trial. Complement Ther Med. 2015 Jun;23(3):318-24. View abstract.
Khonche A, Biglarian O, Panahi Y, et al. Adjunctive therapy with curcumin for peptic ulcer: a randomized controlled trial. Drug Res (Stuttg). 2016 Aug;66(8):444-8. View abstract.
Kia SJ, Basirat M, Mortezaie T, Moosavi MS. Comparison of oral nano-curcumin with oral prednisolone on oral lichen planus: a randomized double-blinded clinical trial. BMC Complement Med Ther 2020;20(1):328. View abstract.
Kia SJ, Basirat M, Saedi HS, Arab SA. Effects of nanomicelle curcumin capsules on prevention and treatment of oral mucosits in patients under chemotherapy with or without head and neck radiotherapy: a randomized clinical trial. BMC Complement Med Ther 2021;21(1):232. View abstract.
Kim IG, Kang SC, Kim KC, Choung ES, Zee OP. Screening of estrogenic and antiestrogenic activities from medicinal plants. Environ Toxicol Pharmacol. 2008;25(1):75-82. View abstract.
Kizhakkedath R. Clinical evaluation of a formulation containing Curcuma longa and Boswellia serrata extracts in the management of knee osteoarthritis. Mol Med Rep 2013;8(5):1542-8. View abstract.
Krizkova, J., Burdova, K., Hudecek, J., Stiborova, M., and Hodek, P. Induction of cytochromes P450 in small intestine by chemopreventive compounds. Neuro.Endocrinol.Lett. 2008;29(5):717-721. View abstract.
Kulkarni RR, Patki PS, Jog VP, et al. Treatment of osteoarthritis with a herbomineral formulation: a double-blind, placebo-controlled, cross-over study. J Ethnopharmacol 1991;33:91-5. View abstract.
Kuptniratsaikul V, Dajpratham P, Taechaarpornkul W, Buntragulpoontawee M, Lukkanapichonchut P, Chootip C, Saengsuwan J, Tantayakom K, Laongpech S. Efficacy and safety of Curcuma domestica extracts compared with ibuprofen in patients with knee osteoarthritis: a multicenter study. Clin Interv Aging 2014;9:451-8. View abstract.
Kuptniratsaikul V, Thanakhumtorn S, Chinswangwatanakul P, et al. Efficacy and safety of Curcuma domestica extracts in patients with knee osteoarthritis. J Altern Complement Med 2009;15:891-7. View abstract.
Kuttan R, Sudheeran PC, Josph CD. Turmeric and curcumin as topical agents in cancer therapy. Tumori 1987;73:29-31.. View abstract.
Lal B, Kapoor AK, Asthana OP, et al. Efficacy of curcumin in the management of chronic anterior uveitis. Phytother Res 1999;13:318-22.. View abstract.
Lang A, Salomon N, Wu JC, et al. Curcumin in combination with mesalamine induces remission in patients with mild-to-moderate ulcerative colitis in a randomized controlled trial. Clin Gastroenterol Hepatol. 2015 Aug;13(8):1444-9. View abstract.
Lasoff DR, Cantrell FL, Ly BT. Death associated with intravenous turmeric (Curcumin) preparation. Clin Toxicol (Phila). 2018;56(5):384-385. View abstract.
Lee BS, Bhatia T, Chaya CT, Wen R, Taira MT, Lim BS. Autoimmune Hepatitis Associated With Turmeric Consumption. ACG Case Rep J. 2020;7(3):e00320. View abstract.
Lee SW, Nah SS, Byon JS, et al. Transient complete atrioventricular block associated with curcumin intake. Int J Cardiol 2011;150:e50-2. View abstract.
Limtrakul, P., Chearwae, W., Shukla, S., Phisalphong, C., and Ambudkar, S. V. Modulation of function of three ABC drug transporters, P-glycoprotein (ABCB1), mitoxantrone resistance protein (ABCG2) and multidrug resistance protein 1 (ABCC1) by tetrahydrocurcumin, a major metabolite of curcumin. Mol.Cell Biochem. 2007;296(1-2):85-95. View abstract.
Lombardi N, Crescioli G, Maggini V, et al. Acute liver injury following turmeric use in Tuscany: an analysis of the Italian Phytovigilance database and systematic review of case reports. Br J Clin Pharmacol. 2020. View abstract.
Lopez-Villafuerte L, CLores KH. Contact dermatitis caused by turmeric in a massage oil. Contact Dermatitis. 2016 Jul;75(1):52-3. View abstract.
Lopresti AL, Smith SJ, Jackson-Michel S, Fairchild T. An investigation into the effects of a curcumin extract (Curcugen ®) on osteoarthritis pain of the knee: A randomised, double-blind, placebo-controlled study. Nutrients 2021;14(1):41. View abstract.
Lorinczova HT, Begum G, Renshaw D, Zariwala MG. Acute Administration of Bioavailable Curcumin Alongside Ferrous Sulphate Supplements Does Not Impair Iron Absorption in Healthy Adults in a Randomised Trial. Nutrients 2021;13(7):2300. View abstract.
Lukefahr AL, McEvoy S, Alfafara C, Funk JL. Drug-induced autoimmune hepatitis associated with turmeric dietary supplement use. BMJ Case Rep. 2018. pii: bcr-2018-224611. View abstract.
Madhu K, Chanda K, Saji MJ. Safety and efficacy of Curcuma longa extract in the treatment of painful knee osteoarthritis: a randomized placebo-controlled trial. Inflammopharmacology 2013;21(2):129-36. View abstract.
Mahammedi H, Planchat E, Pouget M, et al. The new combination docetaxel, prednisone and curcumin in patients with castration-resistant prostate cancer: A pilot phase II study. Oncology. 2016;90(2):69-78. View abstract.
Malekzadeh M, Kia SJ, Mashaei L, Moosavi MS. Oral nano-curcumin on gingival inflammation in patients with gingivitis and mild periodontitis. Clin Exp Dent Res. 2020. doi: 10.1002/cre2.330. Online ahead of print. View abstract.
Mali AM, Behal R, Gilda SS. Comparative evaluation of 0.1% turmeric mouthwash with 0.2% chlorhexidine gluconate in prevention of plaque and gingivitis: A clinical and microbiological study. J Indian Soc Periodontol 2012;16(3):386-91. View abstract.
Manarin G, Anderson D, Silva JME, et al. Curcuma longa L. ameliorates asthma control in children and adolescents: A randomized, double-blind, controlled trial. J Ethnopharmacol. 2019;238:111882. View abstract.
Maulina T, Diana H, Cahyanto A, Amaliya A. The efficacy of curcumin in managing acute inflammation pain on the post-surgical removal of impacted third molars patients: A randomised controlled trial. J Oral Rehabil. 2018;45(9):677-683. View abstract.
Medsafe Safety Communication- Turmeric/Curcumin Interaction with Warfarin. April 30, 2018. Accessed at: https://medsafe.govt.nz/safety/EWS/2018/Turmeric.asp.
Mirhafez SR, Azimi-Nezhad M, Dehabeh M, et al. The effect of curcumin phytosome on the treatment of patients with non-alcoholic fatty liver disease: A double-blind, randomized, placebo-controlled trial. Adv Exp Med Biol. 2021;1308:25-35. View abstract.
Mirhafez SR, Dehabeh M, Hariri M, et al. Curcumin and piperine combination for the treatment of patients with non-alcoholic fatty liver disease: A double-blind randomized placebo-controlled trial. Adv Exp Med Biol 2021;1328:11-19. View abstract.
Mitchell TM. Correspondence re: Somasundaram et al., Dietary curcumin inhibits chemotherapy-induced apoptosis in models of human breast cancer. Cancer Res. 2003;63(16):5165-6; author reply 5166-7. View abstract.
Mohammadi E, Tamaddoni A, Qujeq D, et al. An investigation of the effects of curcumin on iron overload, hepcidin level, and liver function in ß-thalassemia major patients: A double-blind randomized controlled clinical trial. Phytother Res. 2018;32(9):1828-1835. View abstract.
Mokhtari M, Razzaghi R, Momen-Heravi M. The effects of curcumin intake on wound healing and metabolic status in patients with diabetic foot ulcer: a randomized, double-blind, placebo-controlled trial. Phytother Res 2020 Nov 16. doi: 10.1002/ptr.6957. View abstract.
Mousavi SM, Milajerdi A, Varkaneh HK, Gorjipour MM, Esmaillzadeh A. The effects of curcumin supplementation on body weight, body mass index and waist circumference: a systematic review and dose-response meta-analysis of randomized controlled trials. Crit Rev Food Sci Nutr 2020;60(1):171-80. doi: 10.1080/10408398.2018.1517724. View abstract.
Nabekura, T., Kamiyama, S., and Kitagawa, S. Effects of dietary chemopreventive phytochemicals on P-glycoprotein function. Biochem.Biophys.Res Commun. 2-18-2005;327(3):866-870. View abstract.
Naeini F, Tutunchi H, Razmi H, et al. Does nano-curcumin supplementation improve hematological indices in critically ill patients with sepsis? A randomized controlled clinical trial. J Food Biochem 2022;46(5):e14093. View abstract.
Nakagawa Y, Mukai S, Yamada S, et al. Short-term effects of highly-bioavailable curcumin for treating knee osteoarthritis: a randomized, double-blind, placebo-controlled prospective study. J Orthop Sci. 2014 Nov;19(6):933-9. View abstract.
Nakagawa Y, Mukai S, Yamada S, et al. The efficacy and safety of highly-bioavailable curcumin for treating knee osteoarthritis: a 6-month open-labeled prospective study. Clin Med Insights Arthritis Musculoskelet Disord. 2020;13:1179544120948471. View abstract.
Nayeri A, Wu S, Adams E, et al. Acute Calcineurin Inhibitor Nephrotoxicity Secondary to Turmeric Intake: A Case Report. Transplant Proc. 2017;49(1):198-200. View abstract.
Neerati P, Devde R, Gangi AK. Evaluation of the effect of curcumin capsules on glyburide therapy in patients with type-2 diabetes mellitus. Phytother Res. 2014;28(12):1796-800. View abstract.
Nerkar Rajbhoj A, Kulkarni TM, Shete A, Shete M, Gore R, Sapkal R. A comparative study to evaluate efficacy of curcumin and aloe vera gel along with oral physiotherapy in the management of oral submucous fibrosis: a randomized clinical trial. Asian Pac J Cancer Prev 2021;22(S1):107-12. doi: 10.31557/APJCP.2021.22.S1.107. View abstract.
Nicol LM, Rowlands DS, Fazakerly R, Kellett J. Curcumin supplementation likely attenuates delayed onset muscle soreness (DOMS). Eur J Appl Physiol. 2015;115(8):1769-77. View abstract.
Nieman DC, Shanely RA, Luo B, Dew D, Meaney MP, Sha W. A commercialized dietary supplement alleviates joint pain in community adults: a double-blind, placebo-controlled community trial. Nutr J 2013;12(1):154. View abstract.
Nowak KL, Farmer-Bailey H, Wang W, et al. Curcumin therapy to treat vascular dysfunction in children and young adults with ADPKD: A randomized controlled trial. Clin J Am Soc Nephrol 2022;17(2):240-250. View abstract.
Olajide, O. A. Investigation of the effects of selected medicinal plants on experimental thrombosis. Phytother Res 1999;13(3):231-232. View abstract.
Pakfetrat M, Basiri F, Malekmakan L, Roozbeh J. Effects of turmeric on uremic pruritus in end stage renal disease patients: a double-blind randomized clinical trial. J Nephrol 2014;27(2):203-7. View abstract.
Palatty PL, Azmidah A, Rao S, et al. Topical application of a sandal wood oil and turmeric based cream prevents radiodermatitis in head and neck cancer patients undergoing external beam radiotherapy: a pilot study. Br J Radiol. 2014;87(1038):20130490. View abstract.
Panahi Y, Karbasi A, Valizadegan G, et al. Effect of curcumin on severity of functional dyspepsia: a triple blinded clinical trial. Adv Exp Med Biol. 2021;1308:119-126. View abstract.
Panahi Y, Kinpour P, Mohtashami R, Jafari R, Simental-Mendia LE, Sahebkar A. Efficacy and safety of phytosomal curcumin in non-alcoholic fatty liver disease: a randomized controlled trial. Drug Res (Stuttg). 2017 Apr;67(4):244-51. View abstract.
Panahi Y, Saberi-Karimian M, Valizadeh O, et al. Effects of curcuminoids on systemic inflammation and quality of life in patients with colorectal cancer undergoing chemotherapy: A randomized controlled trial. Adv Exp Med Biol 2021;1328:1-9. View abstract.
Panahi Y, Vahedian-Azimi A, Saadat A, et al. The effects of curcumin on the side effects of anticancer drugs in chemotherapy: A randomized controlled trial. Adv Exp Med Biol 2021;1328:255-273. View abstract.
Pandaran Sudheeran S, Jacob D, Natinga Mulakal J, et al. Safety, Tolerance, and Enhanced Efficacy of a Bioavailable Formulation of Curcumin With Fenugreek Dietary Fiber on Occupational Stress: A Randomized, Double-Blind, Placebo-Controlled Pilot Study. J Clin Psychopharmacol. 2016;36(3):236-43. View abstract.
Pashine L, Singh JV, Vaish AK, Ojha SK, Mahdi AA. Effect of turmeric (Curcuma longa) on overweight hyperlipidemic subjects: Double blind study. Indian J Comm Health 2012;24(2):113-117.
Passildas-Jahanmohan J, Eymard JC, Pouget M, et al. Multicenter randomized phase II study comparing docetaxel plus curcumin versus docetaxel plus placebo in first-line treatment of metastatic castration-resistant prostate cancer. Cancer Med. 2021;10(7):2332-2340. View abstract.
Pawar KS, Mastud RN, Pawar SK, et al. Oral curcumin with piperine as adjuvant therapy for the treatment of COVID-19: A randomized clinical trial. Front Pharmacol. 2021;12:669362. View abstract.
Pinsornsak P, Niempoog S. The efficacy of Curcuma Longa L. extract as an adjuvant therapy in primary knee osteoarthritis: a randomized control trial. J Med Assoc Thai 2012;95 Suppl 1:S51-8. View abstract.
Portincasa P, Bonfrate L, Scribano ML, et al. Curcumin and fennel essential oil improve symptoms and quality of life in patients with irritable bowel syndrome. J Gastrointestin Liver Dis. 2016 Jun;25(2):151-7. View abstract.
Pourhabibi-Zarandi F, Rafraf M, Zayeni H, Asghari-Jafarabadi M, Ebrahimi AA. Effects of curcumin supplementation on metabolic parameters, inflammatory factors and obesity values in women with rheumatoid arthritis: A randomized, double-blind, placebo-controlled clinical trial. Phytother Res 2022;36(4):1797-1806. View abstract.
Price, R. J., Scott, M. P., Giddings, A. M., Walters, D. G., Stierum, R. H., Meredith, C., and Lake, B. G. Effect of butylated hydroxytoluene, curcumin, propyl gallate and thiabendazole on cytochrome P450 forms in cultured human hepatocytes. Xenobiotica 2008;38(6):574-586. View abstract.
Qiao J, Gan Y, Gong Y, et al. Combination therapy with curcumin plus tamsulosin and finasteride in the treatment of men with benign prostatic hyperplasia: a single center, randomized control study. Transl Androl Urol 2021;10(8):3432-3439. View abstract.
Qin S, Huang L, Gong J, et al. Efficacy and safety of turmeric and curcumin in lowering blood lipid levels in patients with cardiovascular risk factors: a meta-analysis of randomized controlled trials. Nutr J. 2017;16(1):68. View abstract.
Raghava KV, Sistla KP, Narayan SJ, Yadalam U, Bose A, Mitra K. Efficacy of Curcumin as an Adjunct to Scaling and Root Planing in Chronic Periodontitis Patients: A Randomized Controlled Clinical Trial. J Contemp Dent Pract. 2019;20(7):842-846. View abstract.
Rahmani S, Asgary S, Askari G, et al. Treatment of non-alcoholic fatty liver disease with curcumin: a randomized placebo-controlled trial. Phytother Res. 2016 Sep;30(9):1540-8. View abstract.
Rai A, Kaur M, Gombra V, Hasan S, Kumar N. Comparative evaluation of curcumin and antioxidants in the management of oral submucous fibrosis. J Investig Clin Dent 2019;10(4):e12464. doi: 10.1111/jicd.12464. View abstract.
Rai A, Kumar N, Sharma S, Parveen S, Rasheed A. Turmeric in the management of oral submucous fibrosis: A systematic review and meta-analysis. J Cancer Res Ther. 2021;17(2):327-335. View abstract.
Rainey-Smith SR, Brown BM, Sohrabi HR, et al. Curcumin and cognition: a randomised, placebo-controlled, double-blind study of community-dwelling older adults. Br J Nutr. 2016;115(12):2106-13. View abstract.
Raman P, Pitty R, Krithika CL, Anand SPN, Subramani GP. Topical curcumin and triamcinolone acetonide in recurrent minor aphthous ulcers: a pilot trial. J Contemp Dent Pract 2020;21(8):884-90. View abstract.
Rao S, Dinkar C, Vaishnav LK, Rao P, Rai MP, Fayad R, Baliga MS. The Indian Spice Turmeric Delays and Mitigates Radiation-Induced Oral Mucositis in Patients Undergoing Treatment for Head and Neck Cancer: An Investigational Study. Integr Cancer Ther 2013;13(3):201-210. View abstract.
Rasyid A, Rahman AR, Jaalam K, Lelo A. Effect of different curcumin dosages on human gall bladder. Asia Pac J Clin Nutr 2002;11:314-8.. View abstract.
Rezaie S, Askari G, Khorvash F, Tarrahi MJ, Amani R. Effects of curcumin supplementation on clinical features and inflammation, in migraine patients: A double-blind controlled, placebo randomized clinical trial. Int J Prev Med 2021;12:161. View abstract.
Romiti, N., Tongiani, R., Cervelli, F., and Chieli, E. Effects of curcumin on P-glycoprotein in primary cultures of rat hepatocytes. Life Sci. 1998;62(25):2349-2358. View abstract.
Ryan Wolf J, Heckler CE, Guido JJ, et al. Oral curcumin for radiation dermatitis: a URCC NCORP study of 686 breast cancer patients. Support Care Cancer. 2018;26(5):1543-1552. View abstract.
Saadipoor A, Razzaghdoust A, Simforoosh N, et al. Randomized, double-blind, placebo-controlled phase II trial of nanocurcumin in prostate cancer patients undergoing radiotherapy. Phytother Res. 2019;33(2):370-378. View abstract.
Saber-Moghaddam N, Salari S, Hejazi S, et al. Oral nano-curcumin formulation efficacy in management of mild to moderate hospitalized coronavirus disease-19 patients: An open label nonrandomized clinical trial. Phytother Res 2021 Jan 3. doi: 10.1002/ptr.7004. View abstract.
Saberi-Karimian M, Ghazizadeh H, Mohammadzadeh E, Ferns GA, Ghayour-Mobarhan M, Sahebkar A. Does curcumin have an effect on sleep duration in metabolic syndrome patients? Avicenna J Phytomed. 2021;11(2):190-198. View abstract.
Saeidnia M, Fazeli P, Erfani M, Nowrouzi-Sohrabi P, Tamaddon G, Karimi M. The Effect of Curcumin on Iron Overload in Patients with Beta-Thalassemia Intermedia. Clin Lab 2022;68(3). View abstract.
Salehi M, Mashhadi NS, Esfahani PS, Feizi A, Hadi A, Askari G. The Effects of Curcumin Supplementation on Muscle Damage, Oxidative Stress, and Inflammatory Markers in Healthy Females with Moderate Physical Activity: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial. Int J Prev Med 2021;12:94. View abstract.
Sanmukhani J, Satodia V, Trivedi J, Patel T, Tiwari D, Panchal B, Goel A, Tripathi CB. Efficacy and safety of curcumin in major depressive disorder: a randomized controlled trial. Phytother Res 2014;28(4):579-85. View abstract.
Sawangroj N, Budkaew J, Chumworathayi B. Efficacy of Curcuma longa in treatment of postprandial distress syndrome: an open-label randomized-controlled trial. F1000Res 2019;8:1827. doi: 10.12688/f1000research.20662.1. View abstract.
Scontre VA, Martins JC, de Melo Sette CV, et al. Curcuma longa (Turmeric) for Prevention of Capecitabine-Induced Hand-Foot Syndrome: A Pilot Study. J Diet Suppl. 2018;15(5):606-612. View abstract.
Shafabakhsh R, Asemi Z, Reiner Z, Soleimani A, Aghadavod E, Bahmani F. The effects of nano-curcumin on metabolic status in patients with diabetes on hemodialysis, a randomized, double blind, placebo-controlled trial. Iran J Kidney Dis. 2020;14(4):290-9. View abstract.
Shah BH, Nawaz Z, Pertani SA. Inhibitory effect of curcumin, a food spice from turmeric, on platelet-activating factor- and arachidonic acid-mediated platelet aggregation through inhibition of thromboxane formation and Ca2+ signaling. Biochem Pharmacol 1999;58:1167-72.. View abstract.
Shah S, Rath H, Sharma G, Senapati SN, Mishra E. Effectiveness of curcumin mouthwash on radiation-induced oral mucositis among head and neck cancer patients: a triple-blind, pilot randomised controlled trial. Indian J Dent Res 2020;31(5):718-27. View abstract.
Sharma RA, McLelland HR, Hill KA, et al. Pharmacodynamic and pharmacokinetic study of oral Curcuma extract in patients with colorectal cancer. Clin Cancer Res 2001;7:1894-900.. View abstract.
Shenouda, N. S., Zhou, C., Browning, J. D., Ansell, P. J., Sakla, M. S., Lubahn, D. B., and MacDonald, R. S. Phytoestrogens in common herbs regulate prostate cancer cell growth in vitro. Nutr.Cancer 2004;49(2):200-208. View abstract.
Simental-Mendía LE, Pirro M, Gotto AM Jr, et al. Lipid-modifying activity of curcuminoids: A systematic review and meta-analysis of randomized controlled trials. Crit Rev Food Sci Nutr. 2017:1-10. View abstract.
Singh M, Singh N. Curcumin counteracts the proliferative effect of estradiol and induces apoptosis in cervical cancer cells. Mol Cell Biochem. 2011;347(1-2):1-11. View abstract.
Singla V, Pratap Mouli V, Garg SK, Rai T, Choudhury BN, Verma P, Deb R, Tiwari V, Rohatgi S, Dhingra R, Kedia S, Sharma PK, Makharia G, Ahuja V. Induction with NCB-02 (curcumin) enema for mild-to-moderate distal ulcerative colitis – a randomized, placebo-controlled, pilot study. J Crohns Colitis 2014;8(3):208-14. View abstract.
Skiba MB, Luis PB, Alfarara C, Billheimer D, Schneider C, Funk JL. Curcuminoid content and safety-related markers of quality of turmeric dietary supplements sold in an urban retail marketplace in the United States. Mol Nutr Food Res. 2018 May 29:e1800143 [Epub ahead of print] View abstract.
Small GW, Siddarth P, Li Z, et al. Memory and brain amyloid and tau effects of a bioavailable form of curcumin in non-demented adults: A double-blind, placebo-controlled 18-month trial. Am J Geriatr Psychiatry. 2018;26(3):266-277. View abstract.
Sohal A, Alhankawi D, Sandhu S, Chintanaboina J. Turmeric-induced hepatotoxicity: Report of 2 cases. Int Med Case Rep J 2021;14:849-852. View abstract.
Sohrevardi SM, Heydari B, Azarpazhooh MR, et al. Therapeutic effect of curcumin in women with polycystic ovary syndrome receiving metformin: A randomized controlled trial. Adv Exp Med Biol. 2021;1308:109-117. View abstract.
Somasundaram S, Edmund NA, Moore DT, Small GW, Shi YY, Orlowski RZ. Dietary curcumin inhibits chemotherapy-induced apoptosis in models of human breast cancer. Cancer Res. 2002;62(13):3868-75. View abstract.
Soni TP, Gupta AK, Sharma LM, Singhal H, Sharma S, Gothwal RS. A randomized, placebo-controlled study to evaluate the effect of bio-enhanced turmeric formulation on radiation-induced oral mucositis. ORL J Otorhinolaryngol Relat Spec. 2021:1-11. View abstract.
Srichairatanakool, S., Thephinlap, C., Phisalaphong, C., Porter, J. B., and Fucharoen, S. Curcumin contributes to in vitro removal of non-transferrin bound iron by deferiprone and desferrioxamine in thalassemic plasma. Med.Chem. 2007;3(5):469-474. View abstract.
Srinivasan A, Selvarajan S, Kamalanathan S, Kadhiravan T, Prasanna Lakshmi NC, Adithan S. Effect of Curcuma longa on vascular function in native Tamilians with type 2 diabetes mellitus: A randomized, double-blind, parallel arm, placebo-controlled trial. Phytother Res. 2019;33(7):1898-1911. View abstract.
Sterzi S, Giordani L, Morrone M, Lena E, et al. The efficacy and safety of a combination of glucosamine hydrochloride, chondroitin sulfate, and bio-circumin with exercise in the treatment of knee osteoarthritis: a randomized, double-blind, placebo-controlled study. Eur J Phys Rehabil Med. 2016 Jun;52(3):321-30. View abstract.
Sugiyama T, Nagata J, Yamagishi A, et al. Selective protection of curcumin against carbon tetrachloride-induced inactivation of hepatic cytochrome P450 isozymes in rats. Life Sci 2006;78:2188-93. View abstract.
Suhail FK, Masood U, Sharma A, John S, Dhamoon A. Turmeric supplement induced hepatotoxicity: a rare complication of a poorly regulated substance. Clin Toxicol (Phila). 2020;58(3):216-217. View abstract.
Surh YJ. Anti-tumor promoting potential of selected spice ingredients with antioxidative and anti-inflammatory activities: a short review. Food Chem Toxicol 2002;40:1091-7. View abstract.
Tabaee S, Sahebkar A, Aghamohammadi T, et al. The effects of curcumin plus piperine supplementation in patients with acute myocardial infarction: A randomized, double-blind, and placebo-controlled Trial. Adv Exp Med Biol 2021;1328:199-211. View abstract.
Tabrizi R, Vakili S, Akbari M, et al. The effects of curcumin-containing supplements on biomarkers of inflammation and oxidative stress: A systematic review and meta-analysis of randomized controlled trials. Phytother Res. 2019;33(2):253-262. View abstract.
Takada Y, Bhardwaj A, Potdar P, Aggarwal BB. Nonsteroidal anti-inflammatory agents differ in their ability to suppress NF-kappaB activation, inhibition of expression of cyclooxygenase-2 and cyclin D1, and abrogation of tumor cell proliferation. Oncogene 2004;23:9247-58. View abstract.
Tang, X. Q., Bi, H., Feng, J. Q., and Cao, J. G. Effect of curcumin on multidrug resistance in resistant human gastric carcinoma cell line SGC7901/VCR. Acta Pharmacol Sin. 2005;26(8):1009-1016. View abstract.
Tatapudi R, Abdul Samad SK, Manyam R, Dasari D, Lakshmi RV. Efficacy of curcumin in the treatment of denture stomatitis: A randomized double-blind study. J Oral Maxillofac Pathol 2021;25(2):286-291. View abstract.
Terby S, Shereef M, Ramanarayanan V, Balakrishnan B. The effect of curcumin as an adjunct in the treatment of chronic periodontitis: A systematic review and meta-analysis. Saudi Dent J 2021;33(7):375-385. View abstract.
Thaloor D, Singh AK, Sidhu GS, et al. Inhibition of angiogenic differentiation of human umbilical vein endothelial cells by curcumin. Cell Growth Differ 1998;9:305-12.. View abstract.
Thamlikitkul V, Bunyapraphatsara N, Dechatiwongse T, et al. Randomized double blind study of Curcuma domestica Val. for dyspepsia. J Med Assoc Thai 1989;72:613-20.. View abstract.
Thanawala S, Shah R, Alluri KV, Somepalli V, Vaze S, Upadhyay V. Comparative bioavailability of curcuminoids from a water-dispersible high curcuminoid turmeric extract against a generic turmeric extract: a randomized, cross-over, comparative, pharmacokinetic study. J Pharm Pharmacol. 2021;73(6):816-823. View abstract.
Thanawala S, Shah R, Somepalli V, Alluri KV, Desomayanandam P, Bhuvanendran A. A multicenter, randomized, double-blind, placebo-controlled trial assessing efficacy and safety of a novel low-dose turmeric extract formulation in healthy adults with chronic knee pain. Clin Pharmacol. 2021;13:91-100. View abstract.
Thapliyal R, Deshpande SS, Maru GB. Mechanism(s) of turmeric-mediated protective effects against benzo(a)pyrene-derived DNA adducts. Cancer Lett 2002;175:79-88. View abstract.
Thapliyal R, Maru GB. Inhibition of cytochrome P450 isozymes by curcumins in vitro and in vivo. Food Chem Toxicol 2001;39:541-7. View abstract.
Thomas R, Williams M, Sharma H, Chaudry A, Bellamy P. A double-blind, placebo-controlled randomised trial evaluating the effect of a polyphenol-rich whole food supplement on PSA progression in men with prostate cancer–the U.K. NCRN Pomi-T study. Prostate Cancer Prostatic Dis 2014;17(2):180-6. View abstract.
Tsai IC, Hsu CW, Chang CH, Tseng PT, Chang KV. The effect of curcumin differs on individual cognitive domains across different patient populations: A systematic review and meta-analysis. Pharmaceuticals (Basel) 2021;14(12):1235. View abstract.
Tuntipopipat, S., Judprasong, K., Zeder, C., Wasantwisut, E., Winichagoon, P., Charoenkiatkul, S., Hurrell, R., and Walczyk, T. Chili, but not turmeric, inhibits iron absorption in young women from an iron-fortified composite meal. J Nutr. 2006;136(12):2970-2974. View abstract.
Tuntipopipat, S., Zeder, C., Siriprapa, P., and Charoenkiatkul, S. Inhibitory effects of spices and herbs on iron availability. Int.J Food Sci.Nutr. 2009;60 Suppl 1:43-55. View abstract.
Valentine, S. P., Le Nedelec, M. J., Menzies, A. R., Scandlyn, M. J., Goodin, M. G., and Rosengren, R. J. Curcumin modulates drug metabolizing enzymes in the female Swiss Webster mouse. Life Sci. 4-11-2006;78(20):2391-2398. View abstract.
Varma K, Amalraj A, Divya C, Gopi S. The efficacy of the novel bioavailable curcumin (Cureit) in the management of sarcopenia in healthy elderly subjects: a randomized, placebo-controlled, double-blind clinical study. J Med Food 2021;24(1):40-9. View abstract.
Wang Z, Singh A, Jones G, et al. Efficacy and safety of turmeric extracts for the treatment of knee osteoarthritis: a systematic review and meta-analysis of randomised controlled trials. Curr Rheumatol Rep 2021 Jan 28;23(2):11. doi: 10.1007/s11926-020-00975-8. View abstract.
Wang Z, Zhang Q, Huang H, Liu Z. The efficacy and acceptability of curcumin for the treatment of depression or depressive symptoms: a systematic review and meta-analysis. J Affect Disord 2021;282:242-51. View abstract.
Wu S, Xiao D. Effect of curcumin on nasal symptoms and airflow in patients with perennial allergic rhinitis. Ann Allergy Asthma Immunol. 2016;117(6):697-702.e1. View abstract.
Yang YS, Su YF, Yang HW, Lee YH, Chou JI, Ueng KC. Lipid-lowering effects of curcumin in patients with metabolic syndrome: a randomized, double-blind, placebo-controlled trial. Phytother Res. 2014;28(12):1770-7. View abstract.
Yin J, Wei L, Wang N, Li X, Miao M. Efficacy and safety of adjuvant curcumin therapy in ulcerative colitis: A systematic review and meta-analysis. J Ethnopharmacol 2022;289:115041. View abstract.
Yongwatana K, Harinwan K, Chirapongsathorn S, et al. Curcuma longa Linn Versus Omeprazole in Treatment of Functional Dyspepsia: A Randomized, Double-Blind, Placebo-Controlled Trial. J Gastroenterol Hepatol 2021. View abstract.
Yu JJ, Pei LB, Zhang Y, Wen ZY, Yang JL. Chronic supplementation of curcumin enhances the efficacy of antidepressants in major depressive disorder: A randomized, double-blind, placebo-controlled pilot study. J Clin Psychopharmacol. 2015;35(4):406-10. View abstract.
Yuan F, Wu W, Ma L, et al. Turmeric and curcuminiods ameliorate disorders of glycometabolism among subjects with metabolic diseases: A systematic review and meta-analysis of randomized controlled trials. Pharmacol Res 2022;177:106121. View abstract.
Yue, G. G., Cheng, S. W., Yu, H., Xu, Z. S., Lee, J. K., Hon, P. M., Lee, M. Y., Kennelly, E. J., Deng, G., Yeung, S. K., Cassileth, B. R., Fung, K. P., Leung, P. C., and Lau, C. B. The role of turmerones on curcumin transportation and P-glycoprotein activities in intestinal Caco-2 cells. J Med Food 2012;15(3):242-252. View abstract.
Zegota Z, Gozdzik J, Glogowska-Szelag J. Prospective, multicenter evaluation of a polyherbal supplement alongside standard-of-care treatment for mild knee osteoarthritis. Adv Orthop. 2021;2021:5589597. View abstract.
Zhang F, Altorki NK, Mestre JR, et al. Curcumin inhibits cyclooxygenase-2 transcription in bile acid- and phorbol ester-treated human gastrointestinal epithelial cells. Carcinogenesis 1999;20:445-51. View abstract.
Zhang T, He Q, Liu Y, Chen Z, Hu H. Efficacy and Safety of Curcumin Supplement on Improvement of Insulin Resistance in People with Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Evid Based Complement Alternat Med 2021;2021:4471944. View abstract.
Zhang, W., Tan, T. M., and Lim, L. Y. Impact of curcumin-induced changes in P-glycoprotein and CYP3A expression on the pharmacokinetics of peroral celiprolol and midazolam in rats. Drug Metab Dispos. 2007;35(1):110-115. View abstract.
Zhu LN, Mei X, Zhang ZG, Xie YP, Lang F. Curcumin intervention for cognitive function in different types of people: A systematic review and meta-analysis. Phytother Res. 2019;33(3):524-533. View abstract.
Abdel Fattah, E. A., Hashem, H. E., Ahmed, F. A., Ghallab, M. A., Varga, I., and Polak, S. Prophylactic role of curcumin against cyclosporine-induced nephrotoxicity: Histological and immunohistological study. Gen.Physiol Biophys. 2010;29(1):85-94. View abstract.
Abraham, S. K., Sarma, L., and Kesavan, P. C. Protective effects of chlorogenic acid, curcumin and beta-carotene against gamma-radiation-induced in vivo chromosomal damage. Mutat.Res 1993;303(3):109-112. View abstract.
Adhvaryu, M. R., Reddy, N., and Vakharia, B. C. Prevention of hepatotoxicity due to anti tuberculosis treatment: a novel integrative approach. World J Gastroenterol. 8-14-2008;14(30):4753-4762. View abstract.
Agarwal, K. A., Tripathi, C. D., Agarwal, B. B., and Saluja, S. Efficacy of turmeric (curcumin) in pain and postoperative fatigue after laparoscopic cholecystectomy: a double-blind, randomized placebo-controlled study. Surg Endosc. 6-14-2011; View abstract.
Agrawal, D. K., Saikia, D., Tiwari, R., Ojha, S., Shanker, K., Kumar, J. K., Gupta, A. K., Tandon, S., Negi, A. S., and Khanuja, S. P. Demethoxycurcumin and its semisynthetic analogues as antitubercular agents. Planta Med. 2008;74(15):1828-1831. View abstract.
Ahmed, T. and Gilani, A. H. Inhibitory effect of curcuminoids on acetylcholinesterase activity and attenuation of scopolamine-induced amnesia may explain medicinal use of turmeric in Alzheimer’s disease. Pharmacol Biochem.Behav. 2009;91(4):554-559. View abstract.
Ahmed, T., Enam, S. A., and Gilani, A. H. Curcuminoids enhance memory in an amyloid-infused rat model of Alzheimer’s disease. Neuroscience 6-9-2010; View abstract.
Ahmed, T., Gilani, A. H., Hosseinmardi, N., Semnanian, S., Enam, S. A., and Fathollahi, Y. Curcuminoids rescue long-term potentiation impaired by amyloid peptide in rat hippocampal slices. Synapse 2011;65(7):572-582. View abstract.
Al Zanbagi, N. A. and Zelai, N. T. Two methods for attenuating Toxoplasma gondii tachyzoites RH strain by using ethanol extract of Curcuma longa. J Egypt Soc.Parasitol. 2008;38(3):965-976. View abstract.
Ali, B. H., Al Wabel, N., Mahmoud, O., Mousa, H. M., and Hashad, M. Curcumin has a palliative action on gentamicin-induced nephrotoxicity in rats. Fundam.Clin Pharmacol 2005;19(4):473-477. View abstract.