cbd oil for cancer in dogs

Cbd oil for cancer in dogs

Due to the lack of regulation, there are some products on the market that have not undergone adequate testing and not only contain negligible quantities of CBD, also contain higher levels of THC than you may expect. Use of these products may lead to THC toxicity in your dog. Essentially, they may get “high”.

For dogs with cancer , some studies have suggested that CBD can even lead to a process called cancer apoptosis , which is essentially the death of the cancer cells. It’s worth noting that CBD as a complete treatment method for cancer has not been proven and the research is in its very early days.

Despite growing popularity, CBD still suffers fromsomething of an identity crisis, with some people still people failingto make the distinction between CBD and marijuana. While it’s true thatCBD and marijuana do come from the same plant, the chemical makeup ofthe Cannabis Sativa plant means that the plants harvested for CBD andmarijuana have different properties. To produce CBD oil, a higher CBD concentration of CBD and minimal levels of THC are required, leading producers to favor the hemp plant.

Like for humans, CBD and hemp oils have long been used in traditional communities to treat pain in dogs resulting from a range of illnesses including cancer and muscular injuries.

Drowsiness

Unlike Tetrahydrocannabinol(THC), CBD is not psychoactive, meaning it doesn’t result in thedistinctive ‘high’ that most people associate with marijuana. For thisreason, as well as its ability to provide natural relief from a wholehost of pain and anxiety disorders, CBD is growing in popularity aroundthe world.

A study found that CBD oil is actually a wake agent that will help your dog stay awake during the day, so that it gets more restful sleep at night. But CBD’s mechanism for sleep modulation is still unclear and needs more testing to validate.

While more research is needed in this area to fully explore the potential of CBD to cure disease, it remains highly regarded as a form of pain relief .

May Improve Sleep

If your dog shows any of these cancer warning signs, contact your vet immediately.

The good news is that over half of all canine cancers are treatable if caught early.

1. Henry, J. G., Shoemaker, G., Prieto, J. M., Hannon, M. B., & Wakshlag, J. J. (2020). The effect of cannabidiol on canine neoplastic cell proliferation and mitogen-activated protein kinase activation during autophagy and apoptosis. Veterinary and Comparative Oncology, e12669, e12669. https://doi.org/10.1111/vco.12669

Cannabidiol (CBD) is one of many chemicals identified in the Cannabis sativa plant, commonly known as hemp. It has been used for palliative care in oncology, but recent studies in humans and rodent models show that it may have direct anti-cancer effects. Since there is little data on the effects of CBD in canine cancer, investigators at Cornell University are studying what happens to canine cancer cells when they are exposed to CBD alone or in combination with common chemotherapy drugs (AKC Canine Health Foundation (CHF) Grant 02643-A: Examination of the Effects of Cannabidiol on Canine Neoplastic Cell Apoptosis/Autophagy and Potential for Chemotherapy Resistance or Sensitivity). Results were recently published in Veterinary and Comparative Oncology 1 and offer hope for canine cancer patients.

Cell cultures from different canine cancers (osteosarcoma, mammary carcinoma, and lymphoma) were exposed to various concentrations of CBD alone and in combination with the common chemotherapy drugs doxorubicin and vincristine. CBD oil caused a significant decrease in cancer cell reproduction in all cell lines studied. Use of CBD-rich whole help extract was able to reduce cancer cell reproduction at lower concentrations than CBD oil alone. This is likely due to the ‘entourage effect’ where the mixture of numerous chemicals seems to work in concert to produce a greater effect. The phenomenon needs more study though, since different cancers have different receptors for these chemicals and not all cultured hemp plants contain the same amounts of these chemicals. CBD in combination with the chemotherapy drug vincristine also decreased cancer cell reproduction in a synergistic way – or with greater effect than either chemical alone. When CBD was combined with doxorubicin, the results varied depending on the concentration of each chemical used.

Participate in canine health research by providing samples or by enrolling in a clinical trial. Samples are needed from healthy dogs and dogs affected by specific diseases.

Help Future Generations of Dogs

This study documents the anti-cancer effects of CBD alone and in combination with chemotherapy drugs. It also provides hints as to the mechanisms and pathways that CBD influences in canine cancer cells. Additional study is needed to better understand these mechanisms and define safe and effective dosages for dogs. Whether CBD is used as a primary treatment or to manage the side effects of chemotherapy, additional knowledge will allow for safer and more effective use. CHF and its donors remain committed to exploring new and better treatments for canine cancer, like CBD. Learn more about our cancer research at akcchf.org/oncologyRPA.

Participate in canine health research by providing samples or by enrolling in a clinical trial. Samples are needed from healthy dogs and dogs affected by specific diseases.

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