cbd oil blood clots

Blood coagulation studies were conducted to determine the possible anti-/prothrombotic effect of an organic cannabis extract and the three major cannabinoids, THC, CBD and CBN. The in vitro effect of the cannabis extract on thrombin activity produced an IC50 value of 9.89 mg/ml, compared to THC at 1.79 mg/ml. It was also found that the extract, THC and CBN showed considerable inhibition of thrombin-induced clot formation in vitro with IC50 values of 600, 87 and 83 microg/ml for the extract, THC and CBN respectively. In an in vivo model used to determine clotting times of lean and obese rats treated with a cannabis extract, 50% clotting times were found to be 1.5 and 2 fold greater than their respective control groups, supporting the results obtained in the in vitro model. The study thus shows that Cannabis sativa and the cannabinoids, THC and CBN, display anticoagulant activity and may be useful in the treatment of diseases such as type 2 diabetes in which a hypercoagulable state exists.

CBD oil can interact with some pharmaceuticals negatively given its quality to slow down the cytochrome P-450 enzyme system (a body system responsible for processing toxins). The liver enzymes that make up this particular system help the body process specific medications more easily by breaking them (the medicines) down into smaller parts. CBD inhibits the P-450 enzyme system, which means that these medications remain in the body for longer than desired. This increases the risk of experiencing the side effects tied to these drugs. It’s worth pointing out, though, that combining certain prescribed blood thinners such as Heparin, Dabigatran, and Edoxaban, with CBD oil come with significantly fewer risks (even no known interaction at all). This is because the P-450 enzyme system does not process all pharmaceuticals.

Our bodies have a system called the Cytochrome P-450 System which metabolizes toxins in the body. Antibiotics have an effect on this system, and CBD has also been found to inhibit this system. This can have a negative effect because when CBD inhibits the system, it alters the way the system metabolizes other drugs — such as antibiotics. In rare cases, this can lead to overdosing on the antibiotic because your body is not processing the drug properly.

How CBD oil works?

Another rule of thumb is to look for the grapefruit warning on medications. There are many medications that can have adverse reactions with citrus fruits, particularly grapefruit or grapefruit juice, and this can cause a reaction or an overdose. Generally, if a medication warns against grapefruit, then you should avoid taking CBD on it as well.

Several factors, such as your general tolerance, weight, and health can influence your likelihood to experience some side effects or interactions. Given the many variables that need to be considered, it’s strongly recommended to speak to your doctor before taking CBD oil, especially if you’re taking blood thinning medication. Your healthcare practitioner will need to take into account the processing time of CBD oil and make adjustments to your medication so they can safely add it to your medication regimen, with minimal system disruption. In doing so, you may be asked to start with a lower-than-recommended CBD oil dose (to help build a CBD oil tolerance) and gradually increase over time if required.

How to take CBD Oil and Blood Thinners Safely

There are other ways to use CBD beyond ingesting it, so if you’re fearful of complications, you can always purchase products that will not get absorbed into your bloodstream. Lotions, creams, and salves that are not transdermal and intended to enter the bloodstream might be your best bet.