Dependent on the dosage, the effects CBD will have on the ECS can vary greatly, though they typically work in tandem with each other. In some cases, depending on the serving size of the CBD product at-hand, your CB2 receptors within the ECS could relax the vascular system, allowing blood to flow easier throughout the body, which usually results in lower blood pressure.
When CBD enters the body, it interacts with the endocannabinoid system (ECS), which helps to regulate other bodily functions to achieve homeostasis.
We have no way of knowing for certain, but what if even a portion of the people that report headaches from using CBD oil were just about to get a headache anyway? Likewise, if you used CBD oil to feel relief from a certain discomfort, the headache may simply still be there even though CBD helped with the rest.
Likewise, depending on when you take CBD in the day, its effect on your wakefulness can vary. This was observed in a study on rats’ modulated sleep cycles through CBD’s influence. Through the study, researchers concluded that CBD could modulate wakefulness by activating neurons in the dorsal raphe nucleus (DRD) and hypothalamus.
While there are four basic types of headaches (migraine, tension, sinus, & cluster) there are up to several dozens of different types of headaches and various potential combinations of headaches
Can CBD Make Headache Worse?
At this time, there are no reports of CBD abuse or dependence while using pure CBD.
Stopping CBD oil cold turkey, is it safe?
The actual cause of headaches might be a little more complex than taking a pure and clean high-quality CBD product from a trusted brand.