THC (delta-9-tetrahydrocannabinol) and CBD (cannabidiol) are the two most-researched and well-understood cannabinoids. Cannabis varieties (also known as strains) differ in their THC and CBD levels and in the ratio of THC to CBD. Therapeutic benefits will vary depending on a patient’s biology and the variety selected.
The terms “indica” and “sativa are botanical terms that describe the shape of the different cannabis plants. They are often used to characterize the range of possible effects from a variety of cannabis.
Methods of Administration & Finding the Right Dose
Irving and colleagues assessed the efficacy, safety, and tolerability of once-daily oral CBD-4% THC (CBD-rich extract) for 10 weeks in patients with active ulcerative colitis (N=60) as an adjuvant therapy while on stable dosing of mesalamine therapy. Patients were less tolerant to the CBD-rich extract than placebo, and there were significant protocol deviations in the study. Both groups failed to reach the primary endpoint of clinical remission, and there were no differences in the rates of remission between the groups (28% for the CBD-rich extract and 26% for placebo). Per-protocol analysis showed improvement in patient’s global impression of change and a trend toward improved quality-of-life scores with CBD-rich extract use.
A 2016 review of studies looked into the role of cannabinoids in inflammation and gastrointestinal mucosal defense. The researchers wrote that direct activation of CB1 receptors by cannabinoids helped reduce gastric acid secretion and gastric motor activity. The process also decreased the formation of gastric mucosal lesions induced by alcohol, stress, and NSAIDs.
The data available so far suggests that the answer is ‘yes.’ There is a clear connection between the ECS and the GI tract. Endocannabinoids work with CB receptors all over the body, including the stomach. While CB1 receptors are predominantly found in the brain, CB2 receptors are mainly in the gut. When any digestive system organ gets swollen, these receptors bind with cannabinoids such as CBD to slowly reduce inflammation.
CBD Oil for Digestion
When mentioning digestive problems, most of us probably automatically think of complaints such as stomach ache, diarrhea, and constipation. While these are all genuine issues, they are sadly only a few of the many symptoms of digestive problems.
Depending on the problem one has, there are a variety of things they can buy to help. However, this can become expensive, and the long-term side effects of taking the medication regularly can be damaging.
Does CBD Settle Your Stomach?
There are many forms of CBD worth considering for digestive problems. CBD oils and gummies are among the most popular. However, there is an age-old remedy for stomach issues that could provide extra relief when infused with CBD.