An RCT in 177 patients with refractory cancer pain taking strong opioids (about 270 mg of morphine) compared THC-CBD, THC, and placebo for 2 weeks. 2
-Versus starting THC-CBD, patients’ pain management was the same or better in 38% with repeat THC-CBD, 33% with THC, and 17% with CBD (no statistical difference).
The cannabinoid is especially promising in pediatric medicine, where CBD shows potential as a safe anti-epileptic drug without psychotropic effects. The ability to access CBD-only supplements and high-CBD strains is a major breakthrough for patients, wellness consumers, and cannabis industry professionals alike.
Though high-THC strains still dominate the cannabis scene, breeders have also developed new cultivars that contain over 20 percent CBD and under 1 percent THC.
Cannabinoids are chemical compounds unique to the cannabis plant. These molecules, along with aromatic compounds called terpenes, are thought to have medicinal benefit.
Why you should add a little THC to your CBD
CBD is also being considered as a treatment and prevention for head trauma, as well as in diabetes, pain, cancer, neurodegenerative disease, depression, anxiety, and addiction research.
Far more research is needed to identify when these cannabinoids are best to use in tandem and when it would be better to keep them separate.
The benefits of whole plant medicine
Theoretically, combining the two would create a product with greater muscle relaxant capabilities yet reduced cognitive impairment. Indeed, one biopharmaceutical company has already created a successful multiple sclerosis drug, Sativex, that contains a one-to-one ratio of CBD and THC.
Unfortunately, this means that many other cannabis compounds, like cannabidiol (CBD), have been phased out over time. In fact, an analysis of 600 cannabis samples reported in 2015 found that as percentages of THC increased over time, levels of CBD decreased.