These patients include those who have localised prostate cancer where active surveillance is followed, those with biochemical recurrence after treatment, and patients with metastatic PCa. I have always wondered whether cannabis oil could indeed be a cure for prostate cancer. Unfortunately, I do not see in practice the desired beneficial effect and the PSA values continue to rise. To find some answers, I did a search in scientific literature.
Cannabinoid receptor type 1 (CB1) is mainly found in the brain, and also in the lungs, the reproductive organs, etc. Cannabinoid receptor type 2 (CB2) is usually located in the immune system and in the bones. THC mainly works on CB1 receptors, CBD on CB2 receptors.
Medicinal cannabis must be distinguished from recreational cannabis which is used to achieve a psychotomimetic state of ‘high’. Cannabis strains used for recreational purposes contain a higher THC and lower CBD ratio than cannabis for medicinal use. Usually two cannabis plants are used: cannabis sativa which has a higher THC concentration and cannabis indica which has a higher CBD concentrate. The flavonoids are known for their antioxidant and anti-inflammatory effects. The terpenoids are resins (oil) with a strong odour.
Granted much of the research has focused on the whole cannabis plant and the full spectrum of cannabinoids, raising the question as to whether CBD on its own has as much value. While cannabidiol should provide at least some of the desired benefit, here are the factors to consider:
As with enlarged prostate, cannabidiol may be able to relieve some of the pain, discomfort, and inflammation associated with this condition. What’s more intriguing, cannabidiol may have antibacterial properties that can address the problem at its source. Researchers at the Institute for Molecular Bioscience at the University of Queensland tested the antibacterial properties of CBD and found that it “had a very similar potency to that of common antibiotics.” This is an intriguing development, as antibiotics are the most common treatment solution for prostatitis.
For BPH sufferers, there’s another possible benefit of taking CBD: pain relief. In a comprehensive review of cannabis studies, the National Academies of Sciences, Engineering, and Medicine found that “there is conclusive or substantial evidence that cannabis or cannabinoids are effective for the treatment for chronic pain in adults.” A University of South Carolina School of Medicine study found cannabidiol to be among the most effective cannabinoids for inflammation.
Some research indicates that cannabinoids like cannabidiol may inhibit testosterone production. This may prove beneficial for people who struggle with recurrent BPH. Though researchers point to THC as being the cannabinoid most closely associated with this effect, there may still be value in CBD and other cannabinoids as well.
CBD and Prostate Cancer
Not to be confused with an enlarged prostate, prostatitis is a condition commonly caused by a type of bacteria that enters the prostate from the urinary tract; it can also be caused by a sexually transmitted disease like HIV or chlamydia. The condition may be chronic or acute, and it affects people of all ages.
The term “enlarged prostate” most commonly refers to benign prostatic hyperplasia (BPH). This is a condition where the prostate is enlarged but not affected by cancer. It commonly affects older men and may cause unpleasant symptoms like painful urination, pain in the hips and pelvic area, blood in the urine or semen, painful ejaculation, and frequent urination.
Cannabidiol (CBD) has developed a dedicated following thanks to its perceived effectiveness against anxiety, epilepsy, localized pain, and other conditions. Using CBD oil for issues such as an enlarged prostate is fairly common place, and although research is still limited (and much of the evidence for its efficacy is anecdotal) the popularity of this compound continues to grow. Like THC, CBD is a cannabinoid, an active compound found in cannabis. But unlike THC, CBD is non-psychoactive, so it doesn’t get the user high.
CBD for Prostatitis
Each of these conditions has its own causes, treatments, and implications when it comes to using cannabidiol.
Before we delve into the specifics of CBD for enlarged prostate (and other prostate issues), we need to define the conditions. For the purposes of this article, we’re going to address the three most common prostate issues that men face: