Let us hope that the use of cannabinoids plays a major role in the future of cardiovascular therapies or at the very least, may be used to relieve some of the symptoms of cardiovascular diseases.
thecannabisradar.com, CBD & Statins: Can CBD Replace Statins as Cholesterol Medication?
Anecdotal evidence shows significant interactions of the two medications only in rare cases of long-term usage and high doses of both. Clearly, if you notice any drug interactions, consult your physician.
Many studies suggest that an increase in HDL and a decrease in LDL may lead to a decrease in cardiovascular mortality. Some of the more recent studies suggest that there is no correlation between a higher LDL cholesterol number and the development of cardiovascular disease.
Colorado-based pharmacology inventors, James Smeeding and Mathew Sherwood, of Indication BioScience, have developed a medication combining a cannabinoid with a statin and are awaiting patent approval.
Their findings indicate that the use of cannabinoids may increase the efficiency of the ECS. The fact that they have developed this medication suggests that their risk/benefit assessment of a potential interaction must be quite a low risk. However, in order to satisfy the FDA, it seems reasonable to conclude that more human clinical trials will be required.
While CBD is known for many therapeutic effects, there are few studies suggesting its impact on the removal of plaque and the reduction of LDL. Here are a few that do support this hypothesis:
Can CBD Effectively Replace Statins?
The human body stores cholesterol for future use, but when there is an excess of cholesterol, it gets stored in the arteries. The HDL is used for necessary bodily functions, but the LDL turns into plaque in the arteries. Plaque buildup is what leads to heart disease and strokes. However, statins do not actually remove plaque. They simply block the cholesterol producing enzyme, HMG, which reduces the total amount of cholesterol in the bloodstream. This forces the body to reabsorb the cholesterol from the arteries.
Scientists are unclear on how CBD interacts with statins. Studies indicate that CBD inhibits several of the liver enzymes which are necessary for breaking down statins. The outcome may be an increase in the concentration of statins in the bloodstream approaching toxic levels. With long-term use, this could mean a risk to a patient’s health including more adverse side effects.
But in most cases, it depends on the individual. Some CBD consumers do not experience any adverse effect after they use both simultaneously. But before combining them, it is better to know your reaction and to play safe; it is recommended to avoid taking CBD with sedatives.
Statins are drugs used to reduce cholesterol levels in the human body and help reduce the risk of heart diseases. Some findings show that statins interact with CBD. If a person uses both frequently, it can lead to the increased concentration of medicines causing dangerous chemical accumulation 3 .
Using CBD with some sleep-inducing supplements can lead to the additive sleepy effect. It does not mean that all CBD users will feel it. But medical experts recommend avoiding combining CBD and herbs causing sleepiness when you have to perform some technical operations.
Muscle relaxants, according to some findings, can also cause some interactions with CBD. Researchers classify muscle relaxants interactions with CBD as moderate. But some people experience side effects like dizziness, lack of concentration and confusion 6 .