Increased access to medicinal and recreational cannabis will be accompanied by greater exposure to its chemical constituents, including Δ9-tetrahydrocannabinol (Δ9-THC) and cannabidiol (CBD), the primary nonpsychoactive compound. Increasing attention has focused on CBD, in part, due to its potential therapeutic properties. Relatively little is known about how CBD might interact with other commonly used drugs. While a number of studies have explored the influence of cannabis or Δ9-THC on alcohol consumption and treatment outcomes, few have examined the effects of CBD on alcohol-related outcomes. This article reviews preclinical and human studies examining the effects of CBD administration on alcohol responses. Preliminary preclinical results suggest that CBD can attenuate alcohol consumption and potentially protect against certain harmful effects of alcohol, such as liver and brain damage. Also reviewed herein are the few existing studies involving CBD and alcohol coadministration in humans. The paucity of such studies precludes any definitive conclusions relating to CBD-alcohol interactions. Effects of CBD on alcohol use and potential therapeutic implications for alcohol use disorder are discussed. (PsycINFO Database Record (c) 2019 APA, all rights reserved).
The effects of alcohol on mood are almost comedically well-known. We also have strong reasons to believe CBD, like alcohol, decreases anxiety. Consequently, it helps further reduce inhibitions – which can be good or bad, depending on how you react.
1. CBD Could Increase Intoxication
CBD and alcohol have tumultuous – yet similar – histories. Each faced government resistance and came out on top. But while their backgrounds share some common ground, CBD and alcohol’s effects on the body and central nervous system differ in some areas and are eerily similar in others.
What is CBD?
But if you’re worried about throwing up, CBD might help prevent or relieve nausea. For instance, a 2001 study in the British Journal of Pharmacology observed antiemetic effects in rodents receiving CBD.