If you want to add CBD oil to your dietary supplement regimen, first learn about the potential interactions and side effects that could occur Let's discuss CBD, how it works, and how it interacts with vitamin C. Keep reading to learn more and find out if you can take CBD with vitamins. An easier option to combine CBD and vitamins is to purchase a CBD product that contains a multivitamin. You should choose the CBD delivery method that works best for you, and then determine how to best add the desired vitamins.
Dietary Supplements and CBD Oil: All You Need to Know from Vitamin A to Zinc
Like CBD oil, dietary supplements have gained big-time popularity, and many Americans use them on a daily basis. So, could it hurt to combine the two?
Written by Cathy Rozyczko — Edited by Jason Brett on September 27, 2021
Health supplements are becoming increasingly commonplace as average Americans struggle to meet their recommended daily intake of vitamins and minerals. CBD oil is the newest supplement to join the ranks, but how might it interact with your existing regimen? Are there any combinations you should avoid?
Put your mind to rest with this breakdown of everything you need to know about CBD oil and dietary supplements.
Interactions between CBD and Dietary Supplements
Visit any wellness, grocery, or drug store and you’ll find shelves lined with an array of dietary supplements, from Vitamin A to Zinc. According to the research so far, CBD oil doesn’t produce unwanted effects when taken with a majority of these supplements, and may in fact bolster or complement your current supplement regimen.
While the likelihood of having a negative reaction from the combination of CBD oil and dietary supplements is slim, a factor which increases these odds is the parallel function of both substances.
For example, in the case of pharmaceutical interactions, one has to be careful taking CBD oil in conjunction with any medication which lowers blood pressure, as cannabidiol (CBD) is also known to be hypotensive. When CBD oil and blood pressure medication is used together, the patient’s blood pressure may drop too low and side effects are more likely to occur.
With that said, if you begin to feel undesirable side effects after using CBD oil with your existing dietary supplements, you may wish to reduce your dosage, or remove CBD from your regimen.
Iron and CBD Oil
Not only can CBD oil and iron supplements be taken together safely, but CBD oil can actually guard against some of the negative effects that iron can have on the body. If you think you may consume more than the recommended daily amount (RDA) of iron, using CBD oil is a wise choice.
Excess levels of iron within the brain have been linked to neurodegenerative diseases such as Alzheimer’s and Parkinson’s. A study on an animal test group found that the cognitive decline brought on by iron build-up could be reversed through the use of CBD.
If you currently take an iron supplement, CBD oil could be a crucial precautionary and protective addition to your regimen.
Fish Oil/Omega 3 and CBD Oil
Fish oil supplements are traditionally used for their high volume of Omega-3 fatty acids. There are no known interactions between fish oil and CBD oil, but interestingly, the seeds of the hemp plant are naturally high in both Omega-3 and Omega-6, in an ideal ratio of 1:3, respectively.
If you are taking a fish oil supplement and wish to use CBD oil, you may find you can kill two birds with one stone. If you find a CBD product that uses hemp seed oil as its base, which many do, you could potentially phase out your fish oil supplement altogether.
St John’s Wort and CBD Oil
St John’s Wort is the only supplement on our list that has any potential to produce side effects when used with CBD oil.
The reason for this interaction is discussed later in the article (see “Effects of CBD on Dietary Supplements”), and relates to the cumulative sleep-inducing properties of both supplements when used together. If St John’s Wort makes you feel drowsy, combining it with CBD oil may increase this effect. However, if it does not have this effect on you, or if sleep is desired, then the combination is of no concern.
St John’s Wort can also affect your serotonin levels in a similar way to antidepressants. CBD oil also increases the serotonin available to the body, so you are at increased risk of experiencing side effects related to high serotonin levels like nausea and dizziness.
Chondroitin Sulphate/Glucosamine and CBD Oil
Joint health is a growing issue, with many people turning to supplements such as glucosamine or chondroitin sulphate in the hopes of avoiding or reversing the damage. CBD oil can be used alongside either of these supplements without any known interaction. However, you may find CBD oil works well enough on its own to reduce inflammation of the joints, providing the possibility to remove glucosamine or chondroitin sulfate from your dietary supplement regimen.
As an anti-inflammatory, CBD oil can reduce the cause of joint pain at the source. An animal study on the use of CBD for joint pain found that CBD “significantly reduced joint swelling” and that it had “therapeutic potential for relief of arthritis pain-related behaviors and inflammation without evident side-effects.” For more information about CBD oil and joint pain, check out our CBD guide for people with rheumatoid arthritis.
Other Common Dietary Supplements and CBD Oil
Here are a few more popular supplements and their potential interactions with CBD oil.
|Popular Supplement||Interaction with CBD Oil|
|Calcium||No interaction reported|
|Echinacea||No interaction reported|
|Ginseng||No interaction reported|
|Ginkgo Biloba||CBD may not be metabolized as effectively when taken with ginkgo biloba|
|Vitamin A||No interaction reported|
|Vitamin B6; B12||No interactions reported|
|Vitamin C||No interactions reported|
|Vitamin D||Vitamin D may not be metabolized as well when taken with CBD oil|
The reactions between CBD oil, Ginkgo biloba, and Vitamin D likely have to do with their use of the cytochrome P-450 enzyme system, which is just a fancy name for the enzymes in your liver that help digest toxins and certain medications.
Certain components of Ginkgo biloba have been shown to inhibit this system; cannabidiol (CBD) also inhibits this system. While it’s hard to say what exactly could happen when taking these two supplements together, if you decide to proceed with the combination, do so with caution.
Vitamin D, on the other hand, is metabolized by the P-450 enzyme system. Because CBD oil inhibits this system, the rate and efficacy with which Vitamin D can be broken down and used is decreased. If you currently take a Vitamin D supplement, it may be best to stay away from CBD oil.
Side Effects of CBD and Dietary Supplements
Side effects between CBD oil and dietary supplements are rare. Though, some sources suggest the relaxing qualities of CBD oil, when combined with supplements that have a similar sleep-inducing effect, may produce a strong sedative result.
If you’re thinking about adding CBD oil to your dietary supplement routine to help with insomnia, this cumulative effect could be seen as a positive. However, if sleepiness is not desired, the combination should be avoided.
Some of the most popular dietary supplements that are known to induce sleep are:
- California poppy
- Jamaican dogwood
- St. John’s wort
If you’re currently taking any of the above supplements and are not in need/want of a sleep aid, you should probably avoid taking CBD oil.
How to Take CBD Oil with Dietary Supplements
There are thousands of CBD products available online and in-store, so how do you know where to start? In order to find the safest and most suitable CBD oils, there are a few steps you should follow.
1. Choose a delivery format
The process of combining CBD oil with your dietary supplements starts with choosing a delivery format. CBD oil comes in a variety of forms, including capsules, edibles, vapes, tinctures, drops, and topicals. Choosing a method that is convenient and effective makes getting your daily dose of CBD a breeze.
Here’s a chart breaking down the different delivery methods so you can decide what’s best for your needs and lifestyle.
|Delivery Format||Pros||Cons||Time of Onset||Duration of Effects|
|Edibles and Capsules and Tinctures||Convenient; Discreet; Doesn’t harm the lungs; Familiar; Dosage control||Slow to take effect||30-60 minutes||Edibles/Capsules:4-6 hours; Tinctures/Drops: 2-4 hours|
|Smokables (E.g. Vapes; flower)||Fast acting; Easy to use; Social; Familiar||Non-discreet; Smoking/Vaping are illegal in many public settings; Can feel harsh on the lungs||Instant||45 minutes-1 hour|
|Topicals (E.g. Lotions; balms; gels)||Can be applied directly to the affected area; Bypasses liver metabolism; Long-lasting; Can be worked into daily hygiene routine||Slow to take effect||Varies widely due to factors like hair growth and the amount of fatty tissue||Typically 5+ hours|
|Transdermal Patches||Longest lasting effects; Bypasses liver metabolism; Steady release of CBD into the bloodstream||May take hours to feel effects||Varies depending on the amount of fatty tissue and hair on the skin||1-2 days|
2. Do your research
Your CBD oil is only as good as the plant it was extracted from and the subsequent manufacturing process. In order to get a high quality CBD product, ensure that you buy from companies which use sustainably sourced, organically grown hemp, and perform third-party lab testing. This reduces the risk of any unwanted pesticides, herbicides or chemical additives making their way into your CBD oil.
3. Adjust your dosage
While it can be tempting to start with a large dose, like many other dietary supplements, CBD oil can be wasted in high quantities. Some studies have shown that CBD oil has a level at which its benefits peak, after which they cease to increase with dosage. Instead of paying for stronger CBD oil than you need, start with a lower dosage and increase incrementally until you feel the benefits.
If you’re looking for a starting point, we at CBD Oil Review have tested hundreds of products and come up with the following:
The CBD Oil Review Serving Standard is 25 mg of CBD taken twice daily.
If you’re not feeling the effects you’d like, increase your dosage by 25 mg every 3-4 weeks until you find the benefits you desire.
If you found this article interesting you may also be interested in:
- Iron – National Institutes of Health https://ods.od.nih.gov/factsheets/Iron-HealthProfessional/
- Vanessa Kappel da Silva et al. (2013) Cannabidiol Normalizes Caspase 3, Synaptophysin, and Mitochondrial Fission Protein DNM1L Expression Levels in Rats with Brain Iron Overload: Implications for Neuroprotection – Springer Nature https://link.springer.com/article/10.1007/s12035-013-8514-7
- St. John’s Wort – National Institutes of Health https://www.nccih.nih.gov/health/st-johns-wort
- D C Hammell et al. (2015) Transdermal cannabidiol reduces inflammation and pain-related behaviours in a rat model of arthritis – National Library of Medicine https://pubmed.ncbi.nlm.nih.gov/26517407/
- Lisa L von Moltke et al. Inhibition of human cytochromes P450 by components of Ginkgo biloba – National Library of Medicine https://pubmed.ncbi.nlm.nih.gov/15285849/
- Cannabidiol (CBD) – MedlinePlus https://medlineplus.gov/druginfo/natural/1439.html
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How Does CBD Oil Interact With Vitamin C?
The use of CBD products has been a hot topic within the past few years. Recently, it seems like CBD products have made their way into a great deal of everyday food and personal care items. This growing popularity of CBD products makes consumers who take daily vitamins wonder whether it’s safe to mix CBD and vitamins.
The science for CBD is emerging, implying the need for more research. CBD, vitamins, and dietary supplements used simultaneously shouldn’t counteract or cause any adverse side effects in most cases. However, this may not always be the case with all supplements, especially with fake CBD oil, high doses of either, or non-regulated supplements.
For safety purposes, always check with your doctor before starting or mixing CBD with other medication or supplements. In this post, we’ll discuss CBD, how it works, and how it interacts with vitamin C. Keep reading to learn more and find out if you can take CBD with vitamins. But first, let’s start with the basics.
What Is CBD Oil?
Touted for its extensive range of health benefits, CBD (Cannabidiol) is one of the over 100 chemical compounds known as cannabinoids produced from cannabis. Preliminary findings have shown CBD to treat several ailments ranging from epileptic seizures to everyday aches and pains. CBD has also been shown to help relieve depression and anxiety.
CBD comes in a wide range of products that can be used in several ways, making it easier than ever for users to harness its positive effects. Most of these benefits boil down to CBDs’ anti-inflammatory properties. CBD has similar benefits to the more popular cannabinoid THC (Tetrahydrocannabinol) found in marijuana, without the high-inducing psychoactive effects.
CBD oil describes several products or formulas that are either concentrated or infused with CBD. In most cases, CBD oil will refer to oil containing pure CBD with no other cannabis compounds. Full-spectrum CBD oil contains more than CBD, such as cannabis-derived terpenes, flavonoids, and other cannabinoids.
CBD oil and other CBD products may contain trace amounts of THC, but not enough to produce an intoxicating effect.
What Is Vitamin C, and Why Is It Important?
Vitamin C, also called ascorbic acid, is necessary to repair damaged body tissue and form blood vessels, muscle, cartilage, and collagen in bones. Vitamin C also has potent antioxidant properties. Because your body doesn’t produce or store vitamin C for future use, you need to get it from your diet or as an oral supplement.
Most people get enough vitamin C from a healthy diet. Vitamin C deficiency is more prevalent in people who have a limited diet that doesn’t regularly include fruits and vegetables, certain gastrointestinal conditions, certain types of cancer, or smokers.
Vitamin C and Your Immune System
Perhaps triggered by the recent global pandemic, discussions about the immune system have become commonplace—and with good reason. Simply put, your body has a naturally present immune system that comprises a complex arrangement of cells, tissues, and organs.
The immune system’s primary purpose is to protect your body from being impacted by disease-causing microorganisms (such as bacteria or viruses). A healthy immune system actively protects the body by preventing harmful cells from entering and attacking the body using white blood cells.
A recent study exploring vitamin C and immune function suggests that sufficient levels of vitamin C may potentially help support a healthy immune system by:
Enhancing the potency of white blood cells
Increasing your immune system’s speed and effectiveness
Preventing the body from experiencing a high level of collateral damage caused by an immune response
Can You Take CBD and Vitamins Together?
Current research shows that CBD oil doesn’t typically interact negatively with vitamins and may even enhance some benefits. As with any supplement, users should consume both vitamins and CBD in moderate amounts under the guidance of a healthcare professional.
Since the human body cannot produce organic compounds like vitamins, some people may need supplements. Like vitamins, cannabinoids such as CBD are essential nutrients that the human body cannot produce on its own.
CBD is an essential nutrient because it’s involved in the proper function of the endocannabinoid system (ECS). Experts are still trying to understand the ECS fully. However, scientists have discovered that it regulates several body functions and processes, ranging from appetite and sleep to memory, mood, and reproduction.
CBD interacts with your body’s ECS by stimulating cannabinoid receptors. With hundreds of report found no interactions between CBD and Vitamin C. Since hemp seed oil is a popular carrier oil, it should be safe for those who can take Vitamin C in the form of hemp oil.
If you aim to take CBD oil and get your vitamin C by eating citrus fruit, you could benefit from various desirable benefits. Citrus fruits such as oranges, lemons, limes, grapefruit, and more contain high levels of vitamin C. However, you may have to exercise caution when eating grapefruit with CBD.
Grapefruit has a bit of a history of inhibiting certain enzymes that can alter your body’s interaction with compounds such as CBD. For instance, it may increase the potency of CBD and or slow down the processing of CBD. This interaction between grapefruit and CBD may not necessarily be a bad thing. However, you may have to alter your current dosage.
Taking grapefruit together with CBD may also increase the mild side effects of CBD. While the interaction between grapefruit and CBD is not caused by the vitamins contained in the fruit, it’s something you should know and consider before taking CBD with any other citrus fruits or medication.
Again, before self-administering any substance, even CBD isolate, don’t hesitate to seek advice from a certified physician.
Benefits of Mixing CBD With Vitamin C
Vitamin C and CBD are great companions. The former speeds up your body’s capacity to absorb cannabidiol, further enhancing the effect. Therefore, a combination of vitamin C and CBD protects you from free radicals and strengthens your immune system, vascular system, skin, and bones. And since your body can’t produce its own vitamin C, a combination of CBD and vitamin C makes for a sensible combination.
Where To Buy CBD Oil and CBD Products
As mentioned earlier, the quality of CBD you consume matters. With the proliferation of CBD in the past few years, you want to make sure you’re purchasing products from a reputable seller. CBD is easily accessible online and in walk-in stores. Most retailers like SUPA Naturals stock only high-quality, safe, and potent CBD products.
Here are a few tips to consider when purchasing a CBD product.
Ask for Test Results
A certificate of analysis, or COA, is a quality control measure that confirms whether the product contains the quantities of CBD that the manufacturer advertises or claims. It also lists any possible contamination from chemicals or heavy metals. A COA should come from an independent source and not the manufacturer or brand to ensure accurate and unbiased results.
Find Out the Source of the Hemp
Since CBD oil primarily comes from the hemp plant, be sure to check labels to see whether the retailer says where and how the hemp was grown. That’s crucial because the highest quality CBD oil comes from organically grown hemp plants. That means the farmers don’t use any artificial fertilizers, pesticides, or other synthetic additions.
You also want to choose locally grown hemp because products made with hemp grown overseas may not be subject to any state or federal testing. For online products, check the companies’ websites for that information. Alternatively, you can contact the seller to give details about the source of their hemp.
Choose CO2 Extracted CBD
The CO2 extraction process ensures purity, which is why it’s so crucial for CBD products. The CBD oil produced by CO2 extraction retains its potency without being contaminated by toxic substances. If you’re looking for some of the purest CBD products on the market, CO2 extraction is only a few steps from being a complete isolate, which makes it the best way to go.
Go for Full-Spectrum CBD Oil
Full-spectrum CBD oil contains many cannabinoids beyond only CBD. It may include trace amounts of THC (up to 0.3%) and other hemp plant elements such as terpenes, fatty acids, essential vitamins, protein, and more. These additional compounds help your body process the CBD more efficiently.
A recent study notes there’s some evidence for the “entourage effect,” which hypothesizes that the presence of multiple compounds from the cannabis plant maximizes its health benefits. So, when purchasing CBD products, you might want to consider selecting full-spectrum CBD oil as it contains some of these other beneficial compounds.
Avoid companies that make extravagant CBD claims. An obvious and crucial step is to avoid brands promising to heal cancer, epilepsy, or other diseases in record time. CBD has plenty of benefits and holds much promise, but more research is needed. A brand’s excessive claims are a tell-tale sign that they’re looking to take advantage of uninformed consumers.
Also, it’s wise to check the product label. Because of CBD’s complex legal status, many CBD products on the market have misleading labels. Be careful if the label only mentions cannabinoids in general rather than CBD. Hemp has hundreds of cannabinoids. And since CBD is the most beneficial, any CBD product should indicate how much CBD it contains.
It’s also helpful to know what other terms on the label may mean. Some CBD retailers describe their products as coming from or including hemp oil. In some cases, they may use the term “hemp oil” to mean CBD oil. However, hemp oil comes from the seeds of the hemp plant rather than the flowers and contains minimal amounts of CBD.
The bottom line is always to consult a healthcare professional if you’d like to try CBD. That is especially the case if you’re taking medications/supplements or have a health condition. Unless you have the go-ahead from your doctor, never stop taking your prescription medications and replace them with CBD.
Medications that come with a grapefruit warning will likely interact with CBD oil. However, your doctor may be able to formulate a plan that works for you through close monitoring of the medication levels in your system. That way, you can complement your treatment therapy with CBD oil.
When shopping for CBD oil, choose a product with a COA that’s been tested by a third-party laboratory. That’s the best way to know the compounds the product contains and whether or not it’s safe for use.
At SUPA Naturals, we use superficial CO2 extraction to produce high-quality CBD products from organically grown hemp plants. That means our products contain no solvent residues, toxins, artificial filters, heavy metals, or pesticides. We ensure the consistency of our products with third-party lab reports.
Are you ready to enjoy the benefits of some of the highest quality CBD products on the market? Check out our SUPA Naturals store to find the right products for your needs. You can also try our CBD quiz to see what may work for you. We stock only the most effective and premium CBD products.
Benefits of Taking CBD and Multivitamins
Vitamins are essential nutrients your body’s cells and organs need to function properly. They are called supplements because they supplement the nutrients your body synthesizes and the nutrients consumed in your dietary plan. Supplements also include botanical, amino acid and enzyme supplements, so CBD supplements fall under the botanical category because CBD extracts come from industrial hemp plants. Combining CBD with vitamins and minerals delivers a more powerful entourage effect because the numerous compounds work together to deliver elevated benefits.
What are Multivitamins?
The Food and Drug Administration explains dietary supplements contain a variety of ingredients. They include minerals, vitamins, enzymes and amino acids. Multivitamins contain a minimum of vitamins and minerals and may contain any or all of the other ingredients. Each type of vitamin and mineral plays a role in human health. The National Institutes of Health (NIH) has online fact sheets for each of the different vitamins and minerals found in dietary supplements.
Many CBD products, derived from the industrial hemp plant, are sold as botanical supplements, even though the label may not use those exact words. Per the NIH, federal laws define supplements as products that include an intention to supplement a nutrition plan, contains one or more dietary nutrients or ingredients, is intended to be consumed in some form, and is called a dietary supplement in some manner. Botanicals can be considered dietary supplements when they meet these conditions.
For example, when shopping for CBD on CBD.market, you may see products like CBDfx Multivitamin CBD gummies for men. The product meets the NIH definition for multivitamin supplements. It has CBD plus vitamins A, C, D3, E and B Complex, plus choline and zinc minerals and pantothenic acid (B5). It is edible, and the description makes it clear the product is intended to support your body’s functioning.
Why are Multivitamins Important?
Multivitamins are important for a number of reasons.
- They can restore vitamins and minerals depleted by medications.
- Getting multivitamins ensures you are getting the recommended Daily Value (DV) of essential nutrients.
- Many diets are deficient in one or more essential vitamins and minerals. Each vitamin plays a different role; the following are some examples:
- Vitamin A is an antioxidant that promotes healing; supports bones, skin and connective tissue; helps with iron absorption.
- Vitamin B complex is combination of eight B vitamins, like B6 for a healthy metabolism; B9 for healthy cell growth and DNA formation; B12 that promotes healthy blood cells and nerves and DNA generation.
- Vitamin C is an antioxidant that supports bones, skin and connective tissue; healing; and iron absorption.
- Vitamin D aids calcium absorption; bone building; and healthy nerves, immune system and muscles.
Each mineral has a different role to play also, like the following:
- Calcium supports healthy bones and teeth; enhances nerve functioning; improves muscle movement; helps blood movement throughout the body.
- Zincaids the metabolism and immune system.
- Choline aids the metabolism; cell membranes; neurotransmitter functioning for muscle control and memory; mood; and gene expression.
Most people need to take more than one vitamin each day because their diet, age and/or lifestyle lead to vitamin and mineral deficiencies. A CBD dietary supplement with multivitamins is a simple way to get the essential nutrients lacking in your diet.
Can You Take CBD Oil And Vitamins Together?
Many people are already taking cannabidiol supplements – CBD oil and vitamins blended together or consumed at the same time. Research is extremely limited in this area, but there are numerous medical clinical trials in progress that are testing the impact of CBD on various bodily functions and medical conditions. Research to date has shown that CBD is considered safe in a large majority of people.
So far, consumers taking both CBD and vitamins are not reporting interactions. When taking diet supplements CBD oil that is pure is the best way to start. That way you know there are no other ingredients in the CBD oil that could cause an issue. Much more research is needed, of course.
Does CBD Interact With Vitamins?
CBD is not a medication. In fact, CBD products cannot be labeled as dietary supplements, per federal law. Ironically, it is only because CBD is being heavily researched in important clinical trials.
This is an indication that many medical researchers believe in CBD’s potential to address a number of health issues. Quality CBD companies use legal labeling, so do not let the lack of the word ‘supplement’ on CBD multivitamin labels confuse you. Multivitamins are dietary supplements.
CBD is a compound or botanical, so it will interact in some form with other compounds, vitamins and minerals. This is true for any substance consumed. For most people, the entourage or synergistic effect is beneficial, and side effects are quite rare. The entourage effect means the CBD and vitamins work in a complementary way to promote better health impacts.
Here is the important point to keep in mind. Each person has a unique experience with CBD and with vitamins, minerals, acids and enzymes. It explains why there are CBD supplements sold with a grapefruit warning.
Grapefruit contains compounds that bind and neutralize the CY450 enzymes, mostly in the small intestine, and then assist with breaking down and eliminating drugs from the body.
CBD also binds to and breakdowns two other enzymes, but in the gut and liver. The double inhibition of enzyme action can lead to an unwanted high dose of a medication you are taking.
You should always carefully read the CBD product’s label and the third-party independent lab report to make sure you know what ingredients are in the CBD multivitamin supplements. This is especially true if you have allergies. You should also consult your doctor before taking CBD and vitamins together.
CBD Oil and Vitamin D3
CBD (cannabidiol) is an active compound that interacts with the endocannabinoid system. Certain cannabinoid receptors are activated which is the focus of clinical studies trying to determine the full impacts on the body. Once again, more research is needed.
Vitamin D3 is a vitamin D that is produced automatically by the body when the skin is exposed to sunlight. It is the only form of Vitamin D your body can manufacture on its own. The other form of Vitamin D is Vitamin D2 which comes mostly from plant sources. Vitamin D3 supports healthy immune system functioning.
By combining CBD and Vitamin D, you are likely to enjoy enhanced immune system health and more energy as they complement each other. You are also assured of getting the right amount of Vitamin D3 when you do not get enough sunlight. Vitamin D3 oil is an emulsified vitamin added to CBD oil, gummies or capsules, for example.